Sexdifferencesinheatshockprotein72expressionandlocalizationinratsfollowingrenalischemia-reperfusioninjury
...chemicmembranedestructioncausesinhibitionofNKA,whereasheatshockprotein(HSP)72helpstopreserveit.WetestedthesexdifferencesinpostischemicexpressionofHSP72andcolocalizationwithNKA.Theleftrenalpedicleofuninephrectomizedfemale(F)andmale(M)Wistarratswasclampedfor55minfollowedby2(T2),16(T16),and24h(T24)ofre...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第10期血清CA19-9、CEA和CA72-4联检对结直肠癌的诊断价值
【摘要】目的探讨血清CA19-9、CEA和CA72-4联检对结直肠癌诊断的应用价值。方法应用电化学发光免疫分析91例结直肠癌患者(恶性组)、86例结直肠良性疾病患者(良性组)和81例健康人(对照组)血清中CA19-9、CEA和CA72-4含量水平。...
医源资料库;在线期刊;中华医药杂志;2006年第6卷第1期新生儿超敏C反应蛋白与前白蛋白水平观察与分析
...生24h内的337例新生儿进行hsCRP与PA检测,并分别于入出生72h、7天进行检测,同时把337例新生儿分为感染与非感染两个大组,每个大组细分为非危重组、危重组、极危重组,并再分为足月儿与早产儿组。结果337例新生儿中感染组(...
合作平台;在线期刊;中华现代临床医学杂志;2004年第2卷第9A期Estrogen,HeatShockProteins,andNFBinHumanVascularEndothelium
...Houston,Tex.ABSTRACTBackground—WehypothesizedthatestrogenwouldincreaseHSP72inhumancoronaryarteryendothelialcells(HCAEC),andthatthesewouldbemoresensitivetoestrogenthanourpreviousobservationsinmyocytes.MethodsandResults—HCAECweretreatedwith17?-estradiolortamoxifen,rangingfromphysiologicaltopharmac...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第9期肾小管上皮细胞ATP耗竭再恢复时热休克蛋白72与Paxillin的相互作用
...为了研究肾小管上皮细胞ATP耗竭再恢复时热休克蛋白(HSP)72与桩蛋白(Paxillin)的相互作用和意义。研究者应用代谢抑制剂暂时性阻断肾小管上皮细胞ATP的生成,引起细胞内的ATP耗竭;换用含10mmol/L葡萄糖的DMEM培养液,使细胞内ATP再...
行业资讯;临床快报;肾脏相关Noassociationofp53codon72andp21codon31polymorphismsinTaiwanChinesepatientswithpterygium
...sineitherp53orp21aredetectedinmanytumourcells,3,4andpolymorphismsofp53codon72orp21codon31werefoundtobeassociatedwithmanytumours.5,6Becauseoftheabnormalexpressionofthep53geneinpterygiumepithelium1,2andthereisevidencethathereditaryfactorsmayhavearoleinthedevelopmentofpterygium,7,8itislogicaltosuspectt...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第7期EvidenceforHSP-mediatedcytoskeletalstabilizationinmesothelialcellsduringacuteexperimentalperitonealdialysis
...rassay,basedoncoincubationofcytoskeletalproteinfractionswithrecombinantHSP-72orHSP-72antibodies.Intheratmodel,detachmentofmesothelialcellsfromtheirperitonealmonolayerduringinvivoPDFexposurewasassessedwithandwithoutoverexpressionofHSP-72(byheatconditioning).Invitro,cytoskeletaldisruptiononsublethalPD...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第1期HeatShockProteinsandMitogen-activatedProteinKinasesinSteatoticLiversUndergoingIschemia-Reperfusion:SomeAnswers
...elevelsweremeasuredafterreperfusion.WereportthatpreconditioningincreasedHSP72andheme-oxygenase-1(HO-1)at6and24hoursofreperfusion,respectively.Unlikenonsteatoticlivers,steatoticliversbenefitedfromHSP72activators(geranylgeranylacetone)throughoutreperfusion.ThisprotectionseemedattributabletoHO-1inducti...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第5期HSP72预先诱导对大鼠肝脏长时间低温保存的保护作用
【摘要】目的观察阿霉素(Doxorubicin,DXR)诱导HSP72对大鼠肝脏长时间冷保存的保护作用。方法实验组SD大鼠按1mg/kgDXR给药,对照组给予生理盐水,48h后用4℃林格液和UW液行肝脏原位冷灌注,肝脏UW液4℃保存24、36、48h,检测保存...
资料库;在线期刊;中华现代外科学杂志;2004年第1卷第2期Vasospasmandp53-InducedApoptosisinanExperimentalModelofSubarachnoidHemorrhage
...hisstudy,weinvestigatedtheroleofp53-inducedapoptosisinthevasculatureat24and72hours.Tocompletelyexaminetheapoptoticcascades,keyproteinsofthecaspase-dependent,-independentandmitochondrialpathwayswereexamined.Methods—Inthisstudy,adultratsweredividedinto3groups:sham(n=21),nontreatment(subarachnoidhemo...
医源资料库;在线期刊;中风学杂志;2006年第37卷第7期