RadioprotectiveEffectofHeatShockProteinonSubmandibularGlandsofRats
...ndintheIRfield.Inthepresentstudy,weinvestigatedwhetherheatshockprotein(HSP)25couldbeusedasaradioprotectivemoleculeforradiation-inducedsalivaryglanddamageinrats.HSP25aswellasinducibleHSP70(HSP70i)thatweredeliveredtothesalivaryglandviaanadenoviralvectorsignificantlyamelioratedradiation-inducedsalivary...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第11期StaytunedtoPXR:anorphanactorthatmaynotbeD-structiveonlytobone
...auseofitsabilitytocross-talkwiththevitaminD–responsivegenethatcatabolizes25-hydroxy-vitaminDand1,25-dihydroxyvitaminD.Thiscross-talkbehaviorhasimportanthealthramificationsandcanbemitigatedthroughtheidentificationandtreatmentofPXR-inducedvitaminDdeficiency.Seetherelatedarticlebeginningonpage177Hist...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第1期Associationbetweenserumconcentrationsof25-hydroxyvitaminDandgingivalinflammation
...hepurposeofthisstudywastoevaluatetheassociationbetweenserumconcentrationsof25-hydroxyvitaminD[25(OH)D]andgingivalinflammation.Design:Weanalyzeddatafrom77503gingivalunits(teeth)in6700neversmokersaged13to90yfromthethirdNationalHealthandNutritionExaminationSurvey.Multiplelogisticregressionmodelsadjuste...
医源资料库;在线期刊;美国临床营养学杂志;2005年82卷第3期PTENinhibitsIL-2receptor–mediatedexpansionofCD4+CD25+Tregs
...a,USA.AbstractOneofthegreatestbarriersagainstharnessingthepotentialofCD4+CD25+Tregsasacellularimmunotherapyistheirhypoproliferativephenotype.WehavepreviouslyshownthatthehypoproliferativeresponseofTregstoIL-2isassociatedwithdefectivedownstreamPI3Ksignaling.Here,wedemonstratethattargeteddeletionofthel...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第9期VitaminD,SheddingLightontheDevelopmentofDiseaseinPeripheralArteries
...calconversionof7-dehydrocholesterol(Figure1).Itissubsequentlyhydroxylatedto25-hydroxycholecalciferol[25(OH)D3]intheliverandfinallytotheactivemetabolite,1,25didydroxcholecalciferol[1,25(OH)2D3]inthekidney.2Somedietarysourcesprovideacholecalciferolderivative,withadoublecarbon-carbonatposition22,23know...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第1期RegulatoryTCellsSelectivelyExpressToll-likeReceptorsandAreActivatedbyLipopolysaccharide
...ortthatthesubsetofCD4cellsknowntoexertregulatoryfunctionsinvivo(CD45RBlowCD25+)selectivelyexpressToll-likereceptors(TLR)-4,-5,-7,and-8.ExposureofCD4+CD25+cellstotheTLR-4ligandlipopolysaccharide(LPS)inducesup-regulationofseveralactivationmarkersandenhancestheirsurvival/proliferation.Thisproliferative...
医源资料库;在线期刊;实验医学杂志;2003年第197卷第3期RegulatoryTCellsSelectivelyExpressToll-likeReceptorsandAreActivatedbyLipopolysaccharide
...ortthatthesubsetofCD4cellsknowntoexertregulatoryfunctionsinvivo(CD45RBlowCD25+)selectivelyexpressToll-likereceptors(TLR)-4,-5,-7,and-8.ExposureofCD4+CD25+cellstotheTLR-4ligandlipopolysaccharide(LPS)inducesup-regulationofseveralactivationmarkersandenhancestheirsurvival/proliferation.Thisproliferative...
医源资料库;在线期刊;美国病理学杂志;2003年第162卷第3期TanningisassociatedwithoptimalvitaminDstatus(serum25-hydroxyvitaminDconcentration)andhigherbonemineraldensity
...nningbedthatemitsultravioletBradiation(290315nm)arelikelytohavehigher25-hydroxyvitaminD[25(OH)D]concentrationsthandosubjectswhodonotregularlyuseatanningbed.Objective:Thefirstobjectiveofthisstudywastoascertainwhethersubjectswhoregularlyuseatanningbedhavehigher25(OH)Dconcentrationsthandosubjects...
医源资料库;在线期刊;美国临床营养学杂志;2004年80卷第6期Associationsofdiet,supplementuse,andultravioletBradiationexposurewithvitaminDstatusinSwedishwomenduringwinter
...Bradiation.Design:Inacross-sectionalstudy,weassessedthevitaminDstatus(serum25-hydroxyvitaminD[25(OH)D])of116womenbyusinganenzymeimmunoassay.Thewomencompletedquestionnairescoveringfoodhabits,useofdietarysupplements,andsun-relatedbehavior.Results:Inamultiplelinearregressionmodel,themaindeterminantsofs...
医源资料库;在线期刊;美国临床营养学杂志;2007年86卷第5期角膜移植患者外周血T细胞及其亚群CD25分子表达研究
【摘要】目的观察角膜移植患者外周血T细胞及其亚群CD25分子的表达。方法应用流式细胞仪于手术前1天、术后第1、2、3、8周检测23例角膜移植患者外周血T细胞CD25分子表达。结果角膜高血管化植床组患者术后外周血T细胞CD25分子...
合作平台;在线期刊;中华现代眼科学杂志;2004年10月第2期;实验研究