Interleukin25regulatestype2cytokine-dependentimmunityandlimitschronicinflammationinthegastrointestinaltract
...tudies,UniversityofEdinburgh,EasterBushVeterinaryCentre,Roslin,MidlothianEH259RG,Scotland,UKThecytokineinterleukin(IL)25hasbeenimplicatedintheinitiationoftype2immunitybydrivingtheexpressionoftype2cytokinessuchasIL-5andIL-13,althoughitsroleintheregulationofimmunityandinfection-inducedinflammationisun...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第4期VitaminDandbreastcancer:insightsfromanimalmodels
...UniversityofNotreDame,NotreDame,IN46556.E-mail:jwelsh3{at}nd.edu.ABSTRACT1,25-DihydroxyvitaminD3[1,25(OH)2D3[,thebiologicallyactiveformofvitaminDthatinteractswiththevitaminDreceptor(VDR),isacoordinateregulatorofproliferation,differentiation,andsurvivalofbreastcancercells.Therefore,vitaminDcompoundst...
医源资料库;在线期刊;美国临床营养学杂志;2004年80卷第6期Aprospectiveanalysisofplasma25-hydroxyvitaminDconcentrationsinwhiteandblackprepubertalfemalesinthesoutheasternUnitedStates
...echangesarerace-dependent.Objectives:Theaimsweretoprospectivelyassessplasma25-hydroxyvitaminD[25(OH)D]concentrationsinprepubertalblackandwhitegirls(n=83)livinginnortheastGeorgiaandtodeterminewhether25(OH)Dconcentrationschangewithincreasingage.Design:Plasmasampleswereobtainedannuallyoveratimeframeof1...
医源资料库;在线期刊;美国临床营养学杂志;2007年85卷第1期OptimalvitaminDstatusandserumparathyroidhormoneconcentrationsinAfricanAmericanwomen
...chCenter,WinthropUniversityHospital,Mineola,NY.2Supportedbygrantno.RO1AG15325fromtheNationalInstituteofAging,NationalInstitutesofHealth.3AddressreprintrequestsandcorrespondencetoJFAloia,WinthropUniversityHospital,222StationPlazaNorthSuite510,Mineola,NY11501.E-mail:jaloia{at}winthrop.org.ABSTRA...
医源资料库;在线期刊;美国临床营养学杂志;2006年84卷第3期Lowserumconcentrationsof25-hydroxyvitaminDinolderpersonsandtheriskofnursinghomeadmission
...cyinnursinghomepatientsishigh.Objective:Weaimedtoascertainwhetherlowerserum25-hydroxyvitaminD[25(OH)D]concentrationsincreasetheriskoffuturenursinghomeadmissionandearlydeath.Design:Weincluded1260independent,community-dwellingpersonsaged65ywhowereparticipatingintheLongitudinalAgingStudyAmsterdam(1995&...
医源资料库;在线期刊;美国临床营养学杂志;2006年84卷第3期FailureofHigh-DoseErgocalciferoltoCorrectVitaminDDeficiencyinAdultswithCysticFibrosis
...aminDrepletionalgorithm.Results:Of134adultswithCF,109(81.3%)werefoundtohave25-hydroxyvitaminD(25-OHD)levelsbelowtherecommended30ng/ml.Sixty-sixoftheseadultscompletedtherecommendedcourseof400,000IUoforalergocalciferolover2months,andonlyfive(8%)respondedwithcorrectionoftheirserum25-OHDtothegoalof30ng/...
医源资料库;在线期刊;美国呼吸和危急护理医学;2005年第171卷第7期HypovitaminosisDisassociatedwithinsulinresistanceandßcelldysfunction
...ontoglucosemetabolismisnotwellstudied.Objective:Weinvestigatedtherelationof25-hydroxyvitaminD[25(OH)D]concentrationstoinsulinsensitivityandßcellfunction.Design:Weenrolled126healthy,glucose-tolerantsubjectslivinginCalifornia.Insulinsensitivityindex(ISI)andfirst-andsecond-phaseinsulinresponses(1s...
医源资料库;在线期刊;美国临床营养学杂志;2004年79卷第5期CoexpressionofCD25andCD27identifiesFoxP3+regulatoryTcellsininflamedsynovia
...ics,UniversityofGenoa,16147Genoa,ItalyAbetterunderstandingoftheroleofCD4+CD25+regulatoryTcellsindiseasepathogenesisshouldfollowfromthediscoveryofreliablemarkerscapableofdiscriminatingregulatoryfromactivatedTcells.WereportthattheCD4+CD25+populationinsynovialfluidofjuvenileidiopathicarthritis(JIA)pati...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第11期Serum25-hydroxyvitaminDconcentrationsingirlsaged48ylivinginthesoutheasternUnitedStates
...youngAmericanchildrenhavenotbeenassessed.Objective:Therelationsbetweenserum25-hydroxyvitaminD[25(OH)D]andbonewereexaminedinprepubertalgirls.Design:Inthepresentcross-sectionalstudy,serum25(OH)Dconcentrationwasassessedin168prepubertalgirlsaged48ylivinginthesoutheasternUnitedStateswiththeuseofrad...
医源资料库;在线期刊;美国临床营养学杂志;2006年83卷第1期TcellsthatcannotrespondtoTGF-escapecontrolbyCD4+CD25+regulatoryTcells
...hSanFrancisco,CA940804DynavaxTechnologiesCorporation,Berkeley,CA94710CD4+CD25+regulatoryT(Treg)cellsplayapivotalroleincontroloftheimmuneresponse.Transforminggrowthfactor-(TGF-)hasbeenshowntoberequiredforTregcellactivity;however,preciselyhowitisinvolvedinthemechanismofsuppressionispoorlyunderstood.Us...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第5期