88移植修复下颌后磨牙的临床观察
【摘要】目的用阻生88移植修复下颌后磨牙的临床疗效观察。方法选择符合条件26例,28颗牙,根据X线片88根形成情况分成A、B两组,根完全形成者为A组,尚未完全形成者为B组。A组进行根管治疗后移植,B组不处理根管移植。结果...
医源资料库;在线期刊;中华医学实践杂志;2005年第4卷第10期MurineCerebralMalariaDevelopmentIsIndependentofToll-LikeReceptorSignaling
...tedmicedeficientforsingleTLR1,-2,-3,-4,-6,-7,or-9andtheiradapterproteinsMyD88,TIRAP,andTRIF.Incontrasttolymphotoxin-deficientmice,whichareresistanttoCM,allTLR-deficientmicewereassensitivetofatalCMdevelopmentaswild-typecontrolmiceanddevelopedtypicalmicrovasculardamagewithvascularleakandhemorrhageinth...
医源资料库;在线期刊;美国病理学杂志;2007年第169卷第5期Interleukin1ReceptorDependenceofSerumTransferredArthritisCanbeCircumventedbyToll-likeReceptor4Signaling
...ismisdependentonthesignalingpathwayintermediarymyeloiddifferentiationfactor88(MyD88),suchthatneitherIL-1RnorMyD88-deficientmicedevelopedvisuallydetectablesynovitisaftertransferofarthritogenicsera.TheToll-likereceptors(TLRs)sharethesamesignalingpathwaythroughMyD88astheIL-1R.TheadministrationofaTLR-4l...
医源资料库;在线期刊;实验医学杂志;2003年第197卷第3期Interleukin1ReceptorDependenceofSerumTransferredArthritisCanbeCircumventedbyToll-likeReceptor4Signaling
...ismisdependentonthesignalingpathwayintermediarymyeloiddifferentiationfactor88(MyD88),suchthatneitherIL-1RnorMyD88-deficientmicedevelopedvisuallydetectablesynovitisaftertransferofarthritogenicsera.TheToll-likereceptors(TLRs)sharethesamesignalingpathwaythroughMyD88astheIL-1R.TheadministrationofaTLR-4l...
医源资料库;在线期刊;美国病理学杂志;2003年第162卷第3期Toll-likereceptor9mediatesinnateimmuneactivationbythemalariapigmenthemozoin
...chresponseswereseverelyimpairedinTLR9–/–andmyeloiddifferentiationfactor88(MyD88)–/–,butnotinTLR2,TLR4,TLR7,orToll/interleukin1receptordomain–containingadaptor-inducinginterferon–/–mice.SyntheticHZ,whichisfreeoftheothercontaminants,alsoactivatedinnateimmuneresponsesinvivoinaTLR9-depende...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第1期上海巴斯德所揭示人类重要肿瘤病毒KSHV逃逸天然免疫的新机制
Figure:RTAreducesMyD88proteinlevel10月15日,国际学术期刊JournalofVirology在线发表了中国科学院上海巴斯德研究所蓝柯研究组题为Kaposi‘sSarcoma-AssociatedHerpesvirus-EncodedRTAImpairsInnateImmunityviaUbiquitin-mediatedDegradationofMyD88的研究论文。卡波氏肉...
行业资讯;临床快报;肿瘤相关PI-88用于肝癌术后治疗初显成效
...,澳大利亚Progen公司今日宣布,其研发中的抗癌药物PI–88的Ⅱ期临床试验证实,对肝癌患者手术切除后使用PI–88治疗能够有效延缓肿瘤复发时间。 临床试验数据显示,使用PI–88治疗的患者在30周时的肿瘤复发率约为20%,远...
行业资讯;临床快报;肝胆病PI-88肝癌临床试验取得突破性成果
...GL;NASDAQ:PGLA)于12月12日宣布,其研发中的抗癌药物PI–88的二期临床试验取得突破性成果,该试验证实对于治疗手术切除后的肝癌患者PI–88能够有效延续其75%的肿瘤复发时间。据了解,肝癌是目前世界第四大多发的癌症,并且...
药品天地;专业药学;药学研究VacciniavirusproteinA46RtargetsmultipleToll-like–interleukin-1receptoradaptorsandcontributestovirulence
....WedemonstratethatA46RtargetsthehostTIRadaptorsmyeloiddifferentiationfactor88(MyD88),MyD88adaptor-like,TIRdomain–containingadaptorinducingIFN-(TRIF),andtheTRIF-relatedadaptormoleculeandtherebyinterfereswithdownstreamactivationofmitogen-activatedproteinkinasesandnuclearfactorB.TRIFmediatesactivatio...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第6期TheToll-LikeReceptorAdaptorProteinsMyDandMal/TIRAPContributetotheInflammatoryandDestructiveProcessesinaHumanModelofRheumatoidArthritis
...theexpressionandfunctionofTLR2andTLR4andtheirdownstreamsignalingadaptorsMyD88andMal/TIRAPinsynovialmembraneculturesfromRAtissue.BothTLR2andTLR4weredetectedbyflowcytometry,andstimulationwithTLR2andTLR4ligandsaugmentedthespontaneousproductionoftumornecrosisfactor-,interleukin(IL)-6,andIL-8,indicatingt...
医源资料库;在线期刊;美国病理学杂志;2007年第169卷第2期