HepaticexpressionofscavengerreceptorclassBtypeI(SR-BI)isapositiveregulatorofmacrophagereversecholesteroltransportinvivo
...sylvania,USA.AbstractHepaticexpressionofthescavengerreceptorclassBtypeI(SR-BI)promotesselectiveuptakeofHDLcholesterolbytheliverandisbelievedtoplayaroleintheprocessofreversecholesteroltransport(RCT).WehypothesizedthathepaticSR-BIexpressionisaregulatoroftherateofintegratedmacrophage-to-fecesRCTandused...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第10期KnockdownexpressionandhepaticdeficiencyrevealanatheroprotectiveroleforSR-BIinliverandperipheraltissues
...atory,GenomicsDivision,Berkeley,California,USA.AbstractScavengerreceptorSR-BIhasbeenimplicatedinHDL-dependentatheroprotectivemechanisms.WereportthegenerationofanSR-BIconditionalknockoutmousemodelinwhichSR-BIgenetargetingbyloxPsiteinsertionproducedahypomorphicallele(hypomSR-BI).AttenuatedSR-BIexpress...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第10期Cholesterolbinding,efflux,andaPDZ-interactingdomainofscavengerreceptor–BImediateHDL-initiatedsignaling
...ia,Pennsylvania,USA.5DepartmentofMedicine,DivisionofMolecularMedicine,ColumbiaUniversityCollegeofPhysiciansandSurgeons,NewYork,NewYork,USA.AbstractThebindingofHDLtoscavengerreceptor–BI(SR-BI)mediatescholesterolmovement.HDLalsoinducesmultiplecellularsignals,whichinendotheliumoccurthroughSR-BIandcon...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第4期海南省2007年登革热媒介伊蚊分布调查
...)、容器指数(ContainerIndex,CI)、布雷图指数(BreteauIndex,BI)等,以房屋指数、容器指数和布雷图指数,调查媒介幼虫密度;以捞取积水容器内蚊幼,调查孳生情况。结果全省BI值最高为123,最低为13.3,全省平均BI值37.4;CI值最...
医源资料库;在线期刊;中国热带医学杂志;2008年第8卷第12期Shiftinggears:liverSR-BIdrivesreversecholesteroltransportinmacrophages
...ofecesisobservedinmiceoverexpressinghepaticscavengerreceptorclassBtypeI(SR-BI),whereasinSR-BI–knockoutmice,cholesterolclearanceisdiminished.ThestudydemonstratesthathepaticSR-BIisapositiveregulatorofmacrophageRCTinvivo.Seetherelatedarticlebeginningonpage2870Thetransportofexcesscholesterolfromtheper...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第10期两种药物伍用治疗脑梗死的临床疗效及安全性比较
...美国国立卫生院卒中量表(NIHSS)评分及日常生活能力(BI)评分评定神经功能缺损程度,并监测肝肾功能、血尿常规及心电图。结果治疗组与对照组相比,NIHSS评分在治疗后2周差异有统计学意义(P<0.01),而BI分值在治疗后2周...
医源资料库;在线期刊;中国热带医学杂志;2008年第8卷第1期GenotypicStudyofPneumocystisjiroveciiinHumanImmunodeficiencyVirus-PositivePatientsinThailand
DepartmentofMicrobiology,FacultyofScience,MahidolUniversityRamaVIRd.DepartmentofParasitology,PhramongkutklaoCollegeofMedicine,RatchawithiRd.,Bangkok10400CenterforBiotechnologyandDepartmentofBiotechnology,InstituteofScienceandTechnologyforResearchandDevelopment,MahidolUniversity,Salaya,Nakornpratom73...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第5期Youarerighttoo!
...herelatedarticlebeginningonpage2192InthesmallvillagesofeasternEurope,therabbiwastheundisputedleaderoftheJewishpeopleofhisvillage.Notonlywashethemasterofreligiouswisdomandlaw,butheoftenservedasthearbiterofcivildisputesaswell.Thereistoldthetaleof2individualswhohadamajordisputeandagreedtogototherabbifo...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第8期广西钦州市登革热媒介监测分析
...2只,占80.71%)。6~8月份的蚊幼指数明显高于9、10月份,BI、CI和HI平均为100.8、34.06和58.0,见表1。 2.1.2缸瓦窑幼虫密度:缸瓦窑是陶瓷厂用于摆放泥缸瓦(泥兴)器皿的场所,有大量的白纹伊蚊滋生,我们共调查553只,全部...
医源资料库;在线期刊;中国热带医学杂志;2007年第7卷第9期CholesterylEsterTransferProtein(CETP)ExpressionProtectsAgainstDietInducedAtherosclerosisinSR-BIDeficientMice
...ssionofthehumanCETPtransgeneprotectsagainstdiet-inducedatherosclerosisinSR-BIdeficientmice.MethodsandResults-SR-BIdeficient(-/-)micewerecrossedwithCETPtransgenic(CETPtg)micetoproduceacolonyofSR-BI-/-xCETPtgmiceinaC57Bl/6background.Ageandsexmatchedgroupsofgeneticallymodifiedandwild-typeC57Bl/6micewer...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期