特发性脊柱侧凸褪黑素信号传导通路的研究进展及其临床意义
【关键词】特发性脊柱侧凸褪黑素信号传导通路青少年特发性脊柱侧凸(adolescentidiopathicscoliosis,AlS)是一个复杂的三维脊柱畸形,常累及青春期10~16岁的女孩。AlS的病因尚不清楚,近来褪黑素信号传导通路的深入研究使得褪黑素(...
医源资料库;在线期刊;中国矫形外科杂志;2009年第17卷第1期思茅地区1961~2003年麻风病流行状况分析
...果(χ2=100.32)。结论今后应重点加强麻风病患者家属中少年儿童的健康检查及单D治愈病人的复查,改善少数民族卫生生活质量,提高早期诊断的能力。联合化疗是治疗麻风的最佳手段。关键词麻风病流行状况分析 麻风病在...
医源资料库;在线期刊;中华现代皮肤科学杂志;2004年第1卷第2期幽门螺杆菌HspA和UreB双价侯选疫苗株的构建
...Hp在我国普通人群中的感染率较高,尤其在北方地区和青少年当中其感染率高达(80~100)%。如何预防和根除Hp感染是目前临床治疗的重点。免疫疗法有望成为治疗该类感染性疾病的最有效、最有前景的方法之一。 在Hp的免疫治...
合作平台;医学论文;临床医学与专科论文;检验医学Adenosinemetabolismandmurinestrain–specificIL-4–inducedinflammation,emphysema,andfibrosis
...hatcontrolthetissueeffectsofIL-4,wecomparedtheeffectsofTgIL-4inBalb/candC57BL/6mice.Intheformer,IL-4causedmodesteosinophilicinflammationandmildairwayfibrosisanddidnotshortensurvival.InC57BL/6mice,IL-4causedprofoundeosinophilicinflammation,airwayfibrosis,emphysematousalveolardestruction,andprematured...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第5期ImpactofMouseStrainDifferencesinInnateHindlimbCollateralVasculature
...anceofgeneticbackgroundforcollateralarterydevelopment.MethodsandResults-C57BL/6,BALB/cand129S2/SvmicewerestudiedafterfemoralarteryligationbylaserDopplerimaging,visiblelightoximetry,time-of-flight-magneticresonanceimaging,andtreadmilltesting;C57BL/6andBALB/calsounderwentelectronparamagneticresonance(...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第3期CharacterizationandComparisonofNicotineandCotinineMetabolisminVitroandinVivoinDBA/2andC57BL/6Mice
【关键词】CharacterizationDBA/2andC57BL/6aretwocommonlyusedmousestrainsthatdifferinresponsetonicotine.Previousstudieshaveshownthatthenicotine-metabolizingenzymeCYP2A5differsincoumarinmetabolismbetweenthesetwostrains,suggestingdifferencesinnicotinemetabolism.Nicotinewasmetabolizedtocotinineinvit...
医源资料库;在线期刊;分子药理学杂志;2007年第69卷第3期第五节 近交系的新进展--一、重组近交系
...而不留空间)来表达,品系名称用缩写形式。如BALB/cByXC57BL/6By,记为CXB;C57BL/6JXDBA/2J,记为BXD;C57BL/6JXC3H/HeJ,记为BXH;C57BL/6JXSJL/J,记为BXJ。对于其一组内的不同品系应用阿拉拍数字加一对开线“-”加以区别。如BXD-5,BXD-30;BXH-1...
医源资料库;医源图书馆;教材类;医用实验动物学NaturalKillerCellsandCD4+T-CellsModulateCollateralArteryDevelopment
....1,CD3,andCD4,invadedthecollateralvesselwall.ArteriogenesiswasimpairedinC57BL/6micedepletedforNaturalKiller(NK)-cellsbyanti-NK1.1antibodiesandinNK-cell–deficienttransgenicmice.Arteriogenesiswas,however,unaffectedinJ281-knockoutmicethatlackNK1.1+NaturalKillerT(NKT)-cells,indicatingthatNK-cells,...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第11期High-DensityLipoproteinsEnhanceProgenitor-MediatedEndotheliumRepairinMice
...erasanindexofprogenitor-mediatedendothelialrepair.StudieswereconductedinC57BL/6JandinapolipoproteinE-deficient(apoE-/-)mice.Wealsoinvestigatedthepossibilitythathigh-densitylipoproteins(HDL)maypromoteprogenitor-mediatedendothelialrepair.MethodsandResults-ThoracicaorticsectionsfromC57BL/6JandapoE-/-mi...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第5期RespiratoryVirus-InducedRegulationofAsthma-LikeResponsesinMiceDependsuponCDTCellsandInterferon-Production
...ingthedevelopinglungimmuneenvironment.Incontrast,theinitiationofamoredesirableanti-viralresponsemaybetterpreparethelocalenvironmentandprotectitfromdevelopinganadverselong-termdiseasephenotype.BALB/corC57BL/6miceexposedtorespiratorysyncytialvirus(RSV)infectionatthesametimeasallergensensitizationwerea...
医源资料库;在线期刊;美国病理学杂志;2007年第169卷第12期