ApoptosismodulatesprotectiveimmunitytothepathogenicfungusHistoplasmacapsulatum
DivisionofInfectiousDiseases,VeteransAffairsHospital,UniversityofCincinnatiCollegeofMedicine,Cincinnati,Ohio,USA.AbstractPathogen-inducedapoptosisoflymphocytesisassociatedwithincreasedsusceptibilitytoinfection.Inthisstudy,wedeterminedwhetherapoptosisinfluencedhostresistancetothefungusHistoplasmacaps...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第10期NKcellspromotetransplanttolerancebykillingdonorantigen-presentingcells
TransplantResearchCenter,DepartmentofMedicineandDepartmentofSurgery,BethIsraelDeaconessMedicalCenter,HarvardMedicalSchool,BostonMA02215Naturalkiller(NK)cellsareprogrammedtokilltargetcellswithoutpriorantigenpriming.Becauseoftheirpotentcytolyticactivities,NKcellsareoneofthekeycelltypesinvolvedindisman...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第8期MolecularEpidemiologyofEndemicClostridiumdifficileInfectionandtheSignificanceofSubtypesoftheUnitedKingdomEpidemicStrain(PCRRibotype1)
DepartmentofMicrobiology,LeedsTeachingHospitalsUniversityofLeeds,Leeds,UnitedKingdomABSTRACTWepreviouslyidentifiedtwosubtypesoftheepidemicstrainClostridiumdifficilePCRribotype1,oneclindamycin-sensitivestrain(arbitrarilyprimedPCR[AP-PCR]typeIa)andacloselyrelatedclindamycin-resistantstrain(AP-PCRtypeI...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第6期CD28CostimulationIsRequiredforInVivoInductionofPeripheralToleranceinCD8TCells
1ExperimentalImmunologyBranch,NationalCancerInstitute2NationalInstituteonAging,NationalInstitutesofHealth,Bethesda,MD20892 AbstractTopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferencesWhereasligationofCD28isknowntoprovideacriticalcostimulatorysignalforactivationofCD4Tcells,therequi...
医源资料库;在线期刊;实验医学杂志;2003年第197卷第1期MulticenterEvaluationofaSemiautomated,StandardizedAssayforDetectionofHepatitisBVirusDNAinBloodDonations
InstituteofVirology,UniversityofMilan,MilanTransfusionMedicineandHematologyDepartment,HospitalofSondrio,Sondrio,ItalyScientificAffairs,RocheMolecularSystems,Rotkreuz,SwitzerlandABSTRACTWeevaluatedtheCOBASAmpliscreenhepatitisBvirus(HBV)testusingstandards,seroconversionpanels,consecutivedonations,ands...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第6期CD28CostimulationIsRequiredforInVivoInductionofPeripheralToleranceinCD8TCells
1ExperimentalImmunologyBranch,NationalCancerInstitute2NationalInstituteonAging,NationalInstitutesofHealth,Bethesda,MD20892 Abstract:TopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferences:WhereasligationofCD28isknowntoprovideacriticalcostimulatorysignalforactivationofCD4Tcells,th...
医源资料库;在线期刊;美国病理学杂志;2003年第162卷第1期PathogenEvolutionInVivo:GenomeDynamicsofTwoIsolatesObtained9YearsApartfromaDuodenalUlcerPatientInfectedwithaSingleHelicobacterpyloriSt
PathogenEvolutionGroup,CentreforDNAFingerprintingandDiagnostics,Hyderabad,IndiaINSERMERI10andCentreNationaldeReferencedesCampylobactersetHelicobacters,LaboratoiredeBacteriologie,UniversiteVictorSegalenBordeaux2,FranceServiceHepato-Gastroenterologie,HpitalSaintAndre,Bordeaux,FranceABSTRACTThesurvival...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第8期Multiple,LinkedHumanImmunodeficiencyVirusType1DrugResistanceMutationsinTreatment-ExperiencedPatientsAreMissedbyStandardGenotypeAnalysis
HIVDrugResistanceProgram,NationalCancerInstitute,NationalInstitutesofHealthSAIC-Frederick,FrederickNationalInstituteofAllergyandInfectiousDiseasesCriticalCareMedicineDepartmentClinicLaboratoryofImmunoregulation,NationalInstituteofAllergyandInfectiousDiseases,NationalInstitutesofHealth,Bethesda,Maryl...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期XBP-1specificallypromotesIgMsynthesisandsecretion,butisdispensablefordegradationofglycoproteinsinprimaryBcells
1DepartmentofPathology,HarvardMedicalSchool2DepartmentofImmunologyandInfectiousDiseases,HarvardSchoolofPublicHealth,Boston,MA02115DifferentiationofBcellsintoplasmacellsrequiresX-boxbindingprotein–1(XBP-1).IntheabsenceofXBP-1,Bcellsdevelopnormally,butverylittleimmunoglobulinissecreted.XBP-1controls...
医源资料库;在线期刊;实验医学杂志;2005年第202卷第4期RapidDetectionofOfloxacinResistanceinMycobacteriumtuberculosisbyTwoLow-CostColorimetricMethods:ResazurinandNitrateReductaseAssays
InstituteofTropicalMedicine,MycobacteriologyUnit,Antwerp,BelgiumABSTRACTWehaveevaluatedtheperformanceoftworapid,low-costmethodsforthedetectionofofloxacin(OFX)resistancewith95Mycobacteriumtuberculosisisolatesfromcountrieswithhighmultidrug-resistanttuberculosisendemicity.Resultsobtainedbynitratereduct...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第4期