BoswellicAcidsStimulateArachidonicAcidReleaseand12-LipoxygenaseActivityinHumanPlateletsIndependentofCa2+andDifferentiallyInteractwithPlatel
...id-inducedreleaseofarachidonicacidandthesubsequentmetabolismbyplatelet-type12-li-poxygenase(p12-LO).Both-boswellicacidand3-O-acetyl-11-keto-boswellicacid(AKBA)markedlyenhancedthereleaseofarachidonicacidviacytosolicphospholipaseA2(cPLA2),whereasforgenerationof12-hydro(pero)xyeicosatetraenoicacid[12-H...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第9期RenalexpressionandlocalizationofthefacilitativeglucosetransportersGLUT1andGLUT12inanimalmodelsofhypertensionanddiabeticnephropathy
...yexaminestherenalexpressionofthefacilitativeglucosetransportersGLUT1andGLUT12inratmodelsofdiabeticnephropathy.Sprague-Dawleyandtransgenic(mRen-2)27ratsreceivedeitherstreptozotocin-induceddiabetesorvehicle.GLUT12expressionandlocalizationweredeterminedbyimmunohistochemistry,immunoblotting,insituhybrid...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第1期LackofhemoglobinresponsetoironsupplementationinanemicMexicanpreschoolerswithmultiplemicronutrientdeficiencies
...ntake.Design:RuralMexicanchildrenaged1836mo(n=219)weresupplementedfor12mowitheither20mgFe,20mgZn,bothironandzinc,orplacebo.Childrenwerecategorizedasiron-unsupplemented(IUS;n=109)orironsupplemented(IS;n=108).Hemoglobin,hematocrit,meancorpuscularvolume,meancellhemoglobin,plasmaconcentrationsofmi...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第6期SustainedActivationofCellAdhesionIsaDifferentiallyRegulatedProcessinBLymphopoiesis
...nichesofthebonemarrowmicroenvironmentduringdevelopment.ChemokinessuchasCXCL12,previouslycalledstromalcell–derivedfactor1,areknowntoactivatecellintegrinsofcirculatingleukocytesresultingintransientadhesionbeforeextravasationintotissues.However,thisshort-termeffectdoesnotexplainthemechanismbywhichpro...
医源资料库;在线期刊;实验医学杂志;2003年第197卷第3期SustainedActivationofCellAdhesionIsaDifferentiallyRegulatedProcessinBLymphopoiesis
...nichesofthebonemarrowmicroenvironmentduringdevelopment.ChemokinessuchasCXCL12,previouslycalledstromalcell–derivedfactor1,areknowntoactivatecellintegrinsofcirculatingleukocytesresultingintransientadhesionbeforeextravasationintotissues.However,thisshort-termeffectdoesnotexplainthemechanismbywhichpro...
医源资料库;在线期刊;美国病理学杂志;2003年第162卷第3期用射线照射的IL-12和B7-1转基因细胞进行癌疫苗的研究
【摘要】目的探讨用放射的IL-12和B7-1转基因细胞进行癌疫苗疗法的效果及协同作用。方法将逆转录病毒载体重组的小鼠IL-12、B7-1基因表达载体分别导入小鼠EL-4胸腺瘤细胞,利用转基因细胞治疗观察其抗肿瘤效果。结果转基因细...
合作平台;在线期刊;中华中西医杂志;2004年第5卷第9期;论著中药内外结合治腰椎间盘突出
...苓桂术甘汤加味:桂枝10克,干姜10克,炙甘草9克,茯苓12克,独活12克,苍术12克,羌活12克,木瓜15克,伸筋草15克,熟附子6克,狗脊12克。水煎服,一日两次。 湿热下注型:腰部酸困、疼痛不适,下肢及臀部拘急,痛处就...
中医中药;中医临床;临床讨论以慢性疲劳为主诉的患者血清叶酸、维生素B12测定
【摘要】0.05),中老年组血清维生素B12的发生率明显高于对照组,血清维生素B12浓度明显低于对照组,有统计学非常显著差异(P<0.01)。结论:本文研究发现,血清维生素B12缺乏很可能是中老年人慢性疲劳的原因之一,而青壮...
医源资料库;在线期刊;中国民康医学;2007年第19卷第4期细胞因子IL12、IFNγ与恶性血液病的关系
【关键词】白细胞介素12;干扰素Ⅱ型;血液肿瘤;综述 恶性血液病是严重危害人类健康的一组常见病、多发病,发病机制尚不明确。白细胞介素12(IL12)、干扰素γ(IFNγ)是广泛存在于人体各组织细胞内的细胞...
医源资料库;在线期刊;齐鲁医学杂志;2008年第23卷第2期PeroxisomeProliferator-ActivatedReceptor-2P12APolymorphismandRiskofCoronaryHeartDiseaseinUSMenandWomen
...andexertsantiatherogeniceffects.Acommonalanineforprolinesubstitutionatcodon12inthePPARG2geneisrelatedtolowerreceptoractivity.StudiessuggestthattheA12alleleisassociatedwithreducedriskoftype2diabetes;however,dataontheriskofcoronaryheartdisease(CHD)arescarceandcontroversial.MethodsandResults—Weexamin...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第8期