MultilocusSequenceTypingofNeisseriameningitidisDirectlyfromClinicalSamplesandApplicationoftheMethodtotheInvestigationofMeningococcalDiseas
HealthProtectionAgency,MeningococcalReferenceUnit,NorthWestRegionalLaboratory,ManchesterHealthProtectionAgency,WestMidlandsRegionalLaboratory,BirminghamDepartmentofBiologicalSciences,ManchesterMetropolitanUniversity,Manchester,UnitedKingdomABSTRACTInfectionsassociatedwithNeisseriameningitidisareamaj...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第12期预激综合征、Q-T间期延长并发尖端扭转型室速1例
...前夏天外出购物时突然晕厥而送来我院。急诊心电图示:W-P-W(B型)频发室早,短阵室速,Q-T间期延长(见图1)。入院查体:BP95/60mmHg,心率67~75次/min,未闻及杂音,两肺呼吸音清,腹软,肝脾未及,无听力障碍。血电解质、...
医源资料库;在线期刊;中华医学实践杂志;2006年第5卷第10期AnimmunoglobulinC-reactivesinglechainantibodyfusionproteininducestolerancethroughreceptoreditinginanormalpolyclonalimmunesystem
...edtheuseofmousemodelscarryinguntargetedortargetedantigenreceptortransgenes,whichdistortlymphocytedevelopmentandthereforeprecludeanalysisofatrulynormalimmunesystem.Herewedemonstrateanadvanceininvivoanalysisofimmunetolerancethatovercomestheseshortcomings.Weshowthatcustomsuperantigensgeneratedbysinglec...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第5期Sodiumchannelmutationsinepilepsyandotherneurologicaldisorders
...,Michigan,USA.AbstractSincethefirstmutationsoftheneuronalsodiumchannelSCN1Awereidentified5yearsago,morethan150mutationshavebeendescribedinpatientswithepilepsy.Manyaresporadicmutationsandcauselossoffunction,whichdemonstrateshaploinsufficiencyofSCN1A.Mutationsresultinginpersistentsodiumcurrentarealsoc...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第8期ComparisonofHelicobacterspp.inCheetahs(Acinonyxjubatus)withandwithoutGastritis
...edicine,UniversityofCalifornia,Davis,CaliforniaCheetahConservationFund,Otjiwarongo,NamibiaABSTRACTChronicgastritiscausessignificantmorbidityandmortalityincaptivecheetahsbutisrareinwildcheetahsdespitecolonizationbyabundantspiralbacteria.ThisresearchaimedtoidentifytheHelicobacterspeciesthatwereassocia...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期UseofPCRAnalysesToDefinetheDistributionofRalstoniaSpeciesRecoveredfromPatientswithCysticFibrosis
...eDiseases,UniversityofMichiganMedicalSchool,AnnArbor,Michigan48109ABSTRACTTwonewPCRassays(forRalstoniaspeciesandRalstoniarespiraculi),togetherwithpreviouslypublishedPCRassays,wereusedtoassessRalstoniaisolatesrecoveredfrom111cysticfibrosispatients.Ralstoniamannitolilyticaaccountedfor46%ofisolates,whi...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第7期Astructuralbasisforselectionandcross-speciesreactivityofthesemi-invariantNKTcellreceptorinCD1d/glycolipidrecognition
...a3800,Australia3CancerImmunologyProgram,PeterMacCallumCancerCentre,St.Andrew‘sPlace,EastMelbourne,Victoria3002,Australia4SchoolofBiosciences,UniversityofBirmingham,Edgbaston,BirminghamB152TT,England,UKLittleisknownregardingthebasisforselectionofthesemi-invariantTcellreceptor(TCR)expressedbynatural...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第3期肥大细胞增生、表型分化及凋亡研究进展
...进展。肥大细胞增生症至少有两种病理发生机制,一种为W位点基因突变,另一种为干细胞生长因子的反应性增高。肥大细胞的表型主要受局部微环境中的细胞因子调节,干细胞生长因子可阻止白介素-3撤退后引起的凋亡。通过研...
合作平台;医学论文;基础医学论文;细胞及分子生物学NewMicrosatelliteMultiplexPCRforCandidaalbicansStrainTypingRevealsMicroevolutionaryChanges
...Department,FacultyofMedicine,UniversityofPorto,Porto,PortugalABSTRACTFivenewmicrosatellitelociweredescribedandcharacterizedforuseasmolecularmarkersfortheidentificationandgeneticdifferentiationofCandidaalbicansstrains.Followingthetypingof72unrelatedclinicalisolates,theanalysisrevealedthattheywereallp...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第8期聚丙烯酰胺凝胶电泳法
...微热使溶解,加20%乙醇制成250ml。 (5)染色液取0.25%(W/V)考马斯亮蓝G[250]溶液2.5ml,加12.5%(W/V)三氯醋酸溶液至10ml。 (6)稀染色液取上述染色液2ml,加12.5%(W/V)三氯醋酸溶液至10ml。 (7)脱色液7%醋酸溶液。 3.操作 ...
医药经济;生物技术;实验技术;生化与分子技术