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CD4+CD25+Tcellsprotectagainstexperimentallyinducedasthmaandalterpulmonarydendriticcellphenotypeandfunction
...function.J.Immunol.172:6519–6523.Min,W.P.,D.Zhou,T.E.Ichim,G.H.Strejan,X.Xia,J.Yang,X.Huang,B.Garcia,D.White,P.Dutartre,etal.2003.InhibitoryfeedbackloopbetweentolerogenicdendriticcellsandregulatoryTcellsintransplanttolerance.J.Immunol.170:1304–1312.Frasca,L.,C.Scotta,G.Lombardi,andE.Piccolella.2...
医源资料库；在线期刊；实验医学杂志；2005年第202卷第11期 -
TranscriptionalRegulatorsofAngiogenesis
...available.Furthermore,wewillnotdiscusscertainestablishedpathways,suchashypoxia-induciblefactor1(HIF-1),thathavebeenthesubjectofnumerousreviews.CharacteristicsandFunctionsofSpecificTranscriptionFactorsinAngiogenesisTable1ContinuedSchematicillustratingthesiteofcellularfunctionsandpathwaysregulatedbytr...
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第9期 -
GlycyrrhizicacidaltersKaposisarcoma–associatedherpesviruslatency,triggeringp53-mediatedapoptosisintransformedBlymphocytes
...cleartranslocationofAIFinapoptosisandnecrosis.FASEBJ.14::729-739.Polyak,K.,Xia,Y.,Zweier,J.L.,Kinzler,K.W.,andVogelstein,B.1997..Amodelforp53-inducedapoptosis.Nature.389::300-305.Deisseroth,A.,andDounce,A.L.1970..Catalase:Physicalandchemicalproperties,mechanismofcatalysis,andphysiologicalrole.Physio...
医源资料库；在线期刊；临床研究杂志；2005年第115卷第3期 -
NO/redoxdisequilibriuminthefailingheartandcardiovascularsystem
...Moreover,theoxidaseactivityofHbwouldbeincreasedbychronicvenousandtissuehypoxia(43,79).TheconsequentproductionofROSbyhypoxicrbcsmaydisruptthedeliveryofNOtothevesselwallbyoxidizingthiolacceptors(73,79,S39).Thus,theloweredvenouspO2inHF(78)maycompromisethedeliveryofNObioactivitythatsubservesregulationof...
医源资料库；在线期刊；临床研究杂志；2005年第115卷第3期 -
PhysiologicalRolesofVascularNucleosideTransporters
...servingthevascularintegrityduringconditionsoflimitedoxygenavailability(hypoxia).Indeed,hypoxia-induciblefactor-1-dependentrepressionofNTsresultsinenhancedextracellularadenosinesignalingandthusattenuateshypoxia-associatedincreasesinvascularleakage.Inaddition,vascularNTsalsocontributetocardiacischemic...
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第5期 -
DisparaterolesofATRandATMinimmunoglobulinclassswitchrecombinationandsomatichypermutation
...itiatedbyactivation-inducedcytidinedeaminase.Here,wehavestudiedtheroleofataxiatelangiectasiaandRad3-relatedprotein(ATR)inCSRbyanalyzingtherecombinationaljunctions,resultingfrominvivoswitching,incellsfrompatientswithmutationsintheATRgene.Theproportionofcellsthathaveswitchedtoimmunoglobulin(Ig)AandIgG...
医源资料库；在线期刊；实验医学杂志；2006年第203卷第1期 -
HypoxicinductionofCtgfisdirectlymediatedbyHif-
...gthefibroticeffectsoftransforminggrowthfactor(TGF)-1andhasbeenshowntobehypoxiainducibleinhumanbreastcancercells.Ithasbeensuggestedthathypoxiaisanimportantunderlyingcauseforthedevelopmentofrenalfibrosisthroughthemodulationofprofibroticgenes.Oneofthekeymediatorsofthecell‘sresponsetoloweredoxygenenvi...
医源资料库；在线期刊；美国生理学杂志；2004年第287卷第12期 -
PulmonaryArteryAdventitialFibroblastsCooperatewithVasaVasorumEndothelialCellstoRegulateVasaVasorumNeovascularization
...ascularization,whichoccursinthepulmonaryarterialcirculationinresponsetohypoxia,remainunknown.Here,usingatechniquetoisolateandcultureadventitialfibroblasts(AdvFBs)andvasavasorumendothelialcells(VVECs)fromtheadventitiaofpulmonaryarteries,wereportthathypoxia-activatedpulmonaryarteryAdvFBsexhibitedpro-a...
医源资料库；在线期刊；美国病理学杂志；2006年第168卷第6期 -
LossofSOCS3inThelpercellsresultedinreducedimmuneresponsesandhyperproductionofinterleukin10andtransforminggrowthfactor–1
...xp.Med.201:73–82.Yoshida,H.,S.Hamano,G.Senaldi,T.Covey,R.Faggioni,S.Mu,M.Xia,A.C.Wakeham,H.Nishina,J.Potter,etal.2001.WSX-1isrequiredfortheinitiationofTh1responsesandresistancetoL.majorinfection.Immunity.15:569–578.作者：IchikoKinjyo,HiromasaInoue,ShinjiroHamano,Sa
医源资料库；在线期刊；实验医学杂志；2006年第203卷第4期 -
ProtectiveimmuneresponsesagainstWestNilevirusareprimedbydistinctcomplementactivationpathways
...State,2000.Emerg.Infect.Dis.7:650–653.Fischer,M.B.,M.Ma,S.Goerg,X.Zhou,J.Xia,O.Finco,S.Han,G.Kelsoe,R.G.Howard,T.L.Rothstein,etal.1996.RegulationoftheBcellresponsetoT-dependentantigensbyclassicalpathwaycomplement.J.Immunol.157:549–556.Botto,M.,C.Dell‘Agnola,A.E.Bygrave,E.M.Thompson,H.T.Cook,F....
医源资料库；在线期刊；实验医学杂志；2006年第203卷第5期