PolymorphismoftheHumanImmunodeficiencyVirusType2(HIV-2)ProteaseGeneandSelectionofDrugResistanceMutationsinHIV-2-InfectedPatientsTreatedwi
HpitalBichat-ClaudeBernardINSERMU552,ParisINSERMU330,Bordeaux,FranceInstitutPasteur,Dakar,SenegalABSTRACTWedescribedthebaselinepolymorphismofthehumanimmunodeficiencyvirustype2(HIV-2)proteasegenefrom94treatment-naivepatientsandthelongitudinalfollow-upof17proteaseinhibitor-treatedpatients.Comparedtoth...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期学术报告:GeneticDissectionoftheSenseofSmell
...2005–2008,$400,0002.NIHgrant#:1R03DC008700-0112/01/06–11/30/09,$150,000Title:Encodingofbehaviorallyrelevantolfactorystimuli3.NIHgrant#:1R21DC008628-0112/01/06–11/30/08,$250,000Title:FunctionalOrganizationoftheOlfactoryCortexPUBLICATIONS1.Zou,Z.andBuck,L.Combinatorialeffectsofodorantmixesinolfa...
医学教育;校园动态;中山医科大学(中山大学广州北校区)Parathyroidhormone-dependentendocytosisofrenaltypeIIcNa-Picotransporter
...osphatemicricketswithhypercalciuriaresultsfrommutationsoftherenaltypeIIcNa-Picotransportergene,suggestingthatthetypeIIctransporterplaysaprominentroleinrenalphosphatehandling.ThegoalofthepresentstudywastoinvestigatetheregulationofthetypeIIcNa-Picotransporterbyparathyroidhormone(PTH).TypeIIcNa-Picotra...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第1期Calciumrequirements:newestimationsformenandwomenbycross-sectionalstatisticalanalysesofcalciumbalancedatafrommetabolicstudies
...moutput(Y)equaltocalciumintake(C)]atintakesof741mg/d[95%predictioninterval(PI):507,1035;Y=148.29+0.80C],9.4mg·kgbodywt–1·d–1[95%PI:6.4,12.9;Y=1.44+0.85C],or0.28mg·kcal–1·d–1[95%PI:0.19,0.38;Y=0.051+0.816C].Neitheragenorsexaffectedtheestimateswhencalciumint...
医源资料库;在线期刊;美国临床营养学杂志;2007年86卷第4期Functionalfoods:theFoodandDrugAdministrationperspective
...tigation,treatmentorpreventionofdisease...“(§201(g)(1)(B)oftheFFDCA[Title21UnitedStatesCode(21USC)§321(g)(1)(B)]).Additionally,aproductmaybesubjecttoregulationasadrugifitmakesaclaimthatitisanarticle(otherthanfood)intendedtoaffectthestructureoranyfunctionofthebody(§201(g)(1)(C)oftheF...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第6期C-PeptideColocalizeswithMacrophagesinEarlyArterioscleroticLesionsofDiabeticSubjectsandInducesMonocyteChemotaxisInVitro
...Medicine(P.L.),LeducqCenterforCardiovascularResearch,BrighamandWomen’sHospitalandHarvardMedicalSchool,Boston,MA;andtheHealthSciencesCenter(A.Z.,S.H.,J.S.),LouisianaStateUniversity,NewOrleans,LA.CorrespondencetoNikolausMarx,MD,DepartmentofInternalMedicineII–Cardiology,UniversityofUlm,Robert-Koch-...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第3期Intermittentpressureoverloadtriggershypertrophy-independentcardiacdysfunctionandvascularrarefaction
...dtherolesofdurationandnatureofthestressonthedevelopmentofcardiacfailure.Despiteamildhypertrophicresponse,preservedsystolicfunction,andafavorablefetalgeneexpressionprofile,heartsexposedtointermittentpressureoverloaddisplayedpathologicalfeatures.Importantly,intermittentpressureoverloadcauseddiastolicd...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第6期LesionPatternsandStrokeMechanisminAtheroscleroticMiddleCerebralArteryDisease
...ionpatternswereclassifiedas(1)single(smallperforator2cm;largeperforator2cm;pial;largeterritorial;border-zone)and(2)multiple.ResultsMCAdiseasewasdiagnosedin63patients,32(50.8%)ofwhomshowedmultiplelesions.Concomitantperforatorandpialinfarcts(14/63,P0.001),concomitantperforator,pial,andborder-zoneinfar...
医源资料库;在线期刊;中风学杂志;2005年第36卷第12期RegulationoftheepithelialNa+channel(ENaC)byphosphatidylinositides
【摘要】TheepithelialNa+channel(ENaC)isanend-effectorofdiversecellularsignalingcascades,includingthosewithphosphatidylinositidesecondmessengers.Recentevidencealsosuggeststhatinsomeinstances,phospatidylinositidescandirectlyinteractwithENaCtoincreasechannelactivitybyincreasingchannelopenprobabilit...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第5期InhibitionofRho-KinaseLeadstoRapidActivationofPhosphatidylinositol3-Kinase/ProteinKinaseAktandCardiovascularProtection
FromtheVascularMedicineResearchUnit(S.W.,Y.R.,J.K.L.),BrighamWomen’sHospitalandHarvardMedicalSchool,Cambridge,Mass;theInstituteofPharmacologyandToxicology(A.D.,P.D.),UniversityofSchleswig-Holstein,CampusLübeck,Germany;andtheDepartmentofPhysiology(T.J.S.,Y.G.,R.S.),JeffersonMedicalCollege,ThomasJe...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第10期