Nonneutralizingantibodiesbindingtothesurfaceglycoproteinoflymphocyticchoriomeningitisvirusreduceearlyvirusspread
...onevirusesisunclear.WedemonstratethatcytotoxicTlymphocyte–deficientTgH(KL25)mice,whicharetransgenicfortheheavychainofthelymphocyticchoriomeningitisvirus(LCMV)–neutralizingmonoclonalantibodyKL25,mountafocusedneutralizingantibodyresponsefollowingLCMVinfection,andthatthisresultsintheemergenceofneut...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第8期Contributionof(13)--D-GlucanChromogenicAssaytoDiagnosisandTherapeuticMonitoringofInvasiveAspergillosisinNeutropenicAdultPatients:aComparison
...gillus;Bio-Rad,Marnes-La-Coquette,France)fortheearlydiagnosisofIA(13,16-18,25,31,35,36).(13)--D-Glucan(BG)isacellwallpolysaccharidecomponentspecificforfungiexceptforzygomycetesand,toalesserextent,cryptococci(21).Prokaryotesandviruses,aswellashumancells,lackBG.Itspresenceinbloodandnormallysterilebody...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期RecurrentColonizationofSuccessivelyImplantedTracheoesophagealVocalProsthesesbyaMemberoftheFusariumsolaniSpeciesComplex
...utopportunisticpathogenicpotential,growthat37°Candcycloheximideresistance(25)wereevaluated.Tothisend,thethreestrainswereincubatedonSDAat37°Cfor2weeksandonSDAsupplementedwithcycloheximide(0.5mg/liter)andchloramphenicol(0.05mg/liter)at28°Cfor3weeks.Molecularidentification.Forsequence-basedidentific...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第2期Nonhumanprimatemodelsofasthma
...heAscarismonkeymodeltodemonstratethatintercellularadhesionmolecule(ICAM)-1(25)andendothelialleukocyteadhesionmolecule(ELAM)-1(26)wereimportantforallergen-inducedcellularinfiltrationoftheairways.Morerecently,monoclonalantibodiestohumanIL-5(24)andIL-13(Dr.P.D.Monk,personalcommunication)havebeenshownto...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第12期UseofVariable-NumberTandemRepeatsToExamineGeneticDiversityofNeisseriameningitidis
...withthe2000HajjoutbreakinSaudiArabiacausedbyN.meningitidisserogroupW135(23,25).16SrRNAsequencingwasthemostsensitive(100%)andthemostspecific(98%)methodinidentifyingtheHajj-relatedisolates(22).MLEEandMLSThavebeenconsideredthe“goldstandard“forepidemiologicalstudyofmeningococci.MLEEhasdemonstratedsi...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第4期克补片
...间分别为20、21分),维生素B2最后被洗脱(保留时间约为25分)。对照品溶液的制备取硝酸硫胺约10mg、维生素B2约10mg、维生素B6约15mg、烟酰胺约100mg,精密称定,置100ml量瓶中,加温热至65℃的1%醋酸溶液80ml,于65±5℃水浴中振摇1...
药品天地;专业药学;药品质量标准;西药第八部分TargetingcoagulationfactorXIIprovidesprotectionfrompathologicalthrombosisincerebralischemiawithoutinterferingwithhemostasis
...activityofactivatedFXII(FXIIa)andplasmakallikrein-mediatedactivationofFXII(25,26).Inaccordancewithitseffectsonhumanplasmainvitro(Fig.3A,opentriangles),PCKincreasedtheaPTTinadose-dependentmannerwhenaddedtoplasmafromWTmice(Fig.3A,filledtriangles)butdidnotprolongtheprothrombintime(PT;atestforfactorVIIa...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第3期PhylogeneticAnalysisoftheSpirochetesBorreliaparkeriandBorreliaturicataeandthePotentialforTick-BorneRelapsingFeverinFlorida
...msiorO.parkeriasbothofthesespeciesoftickshavebeencollectedinthegeneralarea(25,37).Additionally,spirochetesnotconsistentwithBorreliaburgdorferi,anagentofLymedisease,wereobservedinbloodsmearsoftwosickdogsinFlorida(13).SpirocheteswereculturedfromthebloodofonedoganddesignatedtheFloridacanineborrelia(FCB...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第8期CharacteristicsofHaemophilusinfluenzaeTypebResponsibleforMeningitisinPolandfrom1997to2004
...vePFGEtypes;however,allofthemwerepossiblyrelated.ThemostcommonPFGEtype,with25subtypes,wascharacteristicfor97.4%oftheisolates.ThemostprevalentPFGEsubtypefoundinourstudywasalsothemostcommonamongtheHibisolatesresponsibleforinvasivediseaseinItalyandtheCzechRepublicandwasfoundamongisolatescausinglowerres...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第11期MultilocusSequenceTypingofPorphyromonasgingivalisStrainsfromDifferentGeographicOrigins
...stsaheterogeneousspecieswithsubpopulationsofhighandlowpathogenicities(7,12,25,32).Ithasalsobeenclaimedthatdifferencesinprogressionratesofinfectionsmaybeduetodifferencesinvirulenceoftheinfectingstrains(13,14,18,24).AnumberofvirulencefactorsareknownforP.gingivalis,includingfimbriae,lipopolysaccharide,...
医源资料库;在线期刊;微生物临床杂志;2006年第44卷第1期