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ProteinphosphatasesubunitG5PRisneededforinhibitionofBcellreceptor–inducedapoptosis
...lutionalScienceandTechnology,JapanScienceandTechnologyAgency,Honcho4-1-8,Kawaguchi,Saitama332-0012,JapanBcellreceptor(BCR)cross-linkinginducesBcellproliferationandsustainssurvivalthroughthephosphorylation-dependentsignals.WereportthatalossoftheproteinphosphatasecomponentG5PRincreasedtheactivation-in...
医源资料库；在线期刊；实验医学杂志；2005年第202卷第5期 -
ForcedusageofpositivelychargedaminoacidsinimmunoglobulinCDR-H3impairsBcelldevelopmentandantibodyproduction
...eandglycineinregulatingCDR-H3contentandpotentiallyinfluencingBcellfunction,wecreatedmicelimitedtoasingleDHencodingasparagine,histidine,andargininesinRF1.TyrosineandglycinecontentinCDR-H3washalved.BonemarrowandspleenmatureBcellandperitonealcavityB-1cellnumberswerealsohalved,whereasmarginalzoneBcellnu...
医源资料库；在线期刊；实验医学杂志；2006年第203卷第6期 -
ComparisonofVisual24-HourandSpectrophotometric48-HourMICstoCLSIReferenceMicrodilutionMICsofFluconazole,Itraconazole,Posaconazole,andVoricona
...da,SpainUniversityofTexasHealthScienceCenter,SanAntonio,TexasUniversityofIowaCollegeofMedicine,IowaCity,IowaMedicalCenterNijmegen,Nijmegen,TheNetherlandsABSTRACTAmulticenter(six-center)studyevaluatedtheperformance(interlaboratoryreproducibility,compatibilitywithreferencemethods,andcategoricalagreeme...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第9期 -
LymphocytesaredetrimentalduringtheearlyinnateimmuneresponseagainstListeriamonocytogenes
DepartmentofPathologyandImmunology,WashingtonUniversitySchoolofMedicine,St.Louis,MO63110MicedeficientinlymphocytesaremoreresistantthannormalmicetoListeriamonocytogenesinfectionduringtheearlyinnateimmuneresponse.Thisparadoxremainsunresolved:lymphocytesarerequiredforsterilizingimmunity,buttheirpresenc...
医源资料库；在线期刊；实验医学杂志；2006年第203卷第4期 -
SensitivitiesandSpecificitiesofSpoligotypingandMycobacterialInterspersedRepetitiveUnit-Variable-NumberTandemRepeatTypingMethodsforStudyingMole
...ferspromiseforreal-timemolecularepidemiologicalstudiesoftuberculosis(TB).However,theutilityofthesemethodsdependsontheircapacitytoappropriatelyclassifyisolates.TodeterminetheoperatingparametersofspoligotypingandMIRU-VNTRtyping,wehavecomparedresultsgeneratedbythesenewerteststothestandardtypingmethod,I...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第1期 -
09年度国家科技奖励各奖项建议授奖项目公布
...附件：1.2009年度国家自然科学奖建议授奖项目目录http://www.most.gov.cn/tztg/200908/W020090803571684408199.pdf序号项目名称主要完成人推荐单位建议授奖等级1《中国植物志》的编研钱崇澍，陈焕镛，吴征镒，王文采，李锡文，胡启明，陈艺...
医学教育；科教新闻 -
MolecularEpidemiologyofNeisseriameningitidisIsolatedintheAfricanMeningitisBeltbetween1988and2003ShowsDominanceofSequenceType5(ST-5)andS
FrenchForcesInstituteofTropicalMedicine(IMTSSA),WHOCollaboratingCentreforReferenceandResearchonMeningococci,LePharo,BP46,13998Marseille,FranceWHOCollaboratingCentreforReferenceandResearchonMeningococci,NorwegianInstituteofPublicHealth,Oslo,NorwayHpitald‘InstructiondesArmeesAlphonseLaveran,Marseill...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第10期 -
MSH2–MSH6stimulatesDNApolymerase,suggestingaroleforA:Tmutationsinantibodygenes
...apanActivation-inducedcytidinedeaminasedeaminatescytosinetouracil(dU)inDNA,whichleadstomutationsatC:Gbasepairsinimmunoglobulingenesduringsomatichypermutation.ThemechanismthatgeneratesmutationsatA:Tbasepairs,however,remainsunclear.ItappearstorequiretheMSH2–MSH6mismatchrepairheterodimerandDNApolymer...
医源资料库；在线期刊；实验医学杂志；2005年第201卷第4期 -
TyrosinePhosphorylationofCagAfromChineseHelicobacterpyloriIsolatesinAGSGastricEpithelialCells
...ity,Zhenjiang,Jiangsu,ChinaInstituteofInfection,Immunity,andInflammationandWolfsonDigestiveDiseasesCentre,UniversityofNottingham,Queen‘sMedicalCentre,Nottingham,UnitedKingdomABSTRACTHelicobacterpyloristrainspossessingthecagpathogenicityisland(PaI)areassociatedwiththedevelopmentofgastroduodenaldise...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第2期 -
Inhibitor-BasedMethodsforDetectionofPlasmid-MediatedAmpC-LactamasesinKlebsiellaspp.,Escherichiacoli,andProteusmirabilis
...er,Richmond,Virginia23249-0001ABSTRACTNon-beta-lactaminhibitor-basedmethodswereevaluatedfordetectingplasmid-mediatedAmpC-lactamasesinKlebsiellaspp.,Escherichiacoli,andProteusmirabilis.UsingCLSImethodologyanddiskscontainingcefotetanaloneandincombinationwith400μgofboronicacid,9of10positivecontrolstra...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第8期