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正相硅胶/选择洗脱—气相色谱法、液相色谱—质谱法检测
...刘荔彬)，HashiYuKi(端裕树)，QinYaPing(秦亚萍)，ZhouHaiXia(周海霞)，LinJinMing(林金明).ChineseJ.Anal.Chem.(分析化学)，2006，34(6)：783～786 10SuJianFeng(苏建峰)，LinGuYuan(林谷园)，LianWenHao(连文浩)，ZhangJinHu(张金虎)，ChenDong...
药品天地；专业药学；实验技术；色谱技术；色谱分析实例 -
Cell-BasedandBiochemicalStructure-ActivityAnalysesofAnalogsoftheMicrotubuleStabilizerDictyostatin
...favorableinteractionwithPhe270inthehydrophobicbindingpocketofthetaxoidsite(Xiaetal.,2006).Theimportanceofthisinteractionhasbeenconfirmedbythedecreaseofnucleatingabilityof14-normethyldiscodermolideintubulinpolymerizationassays(Smithetal.,2005).Atwo-dimensionalNMR-derivedbindingmodelofepothiloneAtothe...
医源资料库；在线期刊；分子药理学杂志；2008年第70卷第3期 -
Acidosisimpairsinsulinreceptorsubstrate-1-associatedphosphoinositide3-kinasesignalinginmusclecells:consequencesonproteolysis
...inASJr.NF-B-inducedlossofMyoDmessengerRNA:possibleroleinmuscledecayandcachexia.Science289:2363-2366,2000.KanetyH,FeinsteinR,PapaMZ,HemiR,andKarasikA.Tumornecrosisfactor-inducedphosphorylationofinsulinreceptorsubstrate-1(IRS-1).Possiblemechanismforsuppressionofinsulin-stimulatedtyrosinephosphorylatio...
医源资料库；在线期刊；美国生理学杂志；2004年第287卷第10期 -
制备色谱技术与操作及实验经验
...6问：多肽的分离制备,如何上量？如何增大分离度?答：[xia][888wym]反相HPLC应当是很好的分离小肽方法，用CH3CN或CH3OH：H2O（95：5）做流动相，看保留如何，若无保留，建议改用其他色谱方法进行分离。关于多肽的分离，首先要知道...
药品天地；专业药学；实验技术；色谱技术；色谱入门 -
Hypoxia-InducedPulmonaryVascularRemodelingRequiresRecruitmentofCirculatingMesenchymalPrecursorsofaMonocyte/MacrophageLineage
...sideredtheprimarycontributorstotheseprocesses,wetestedthehypothesisthathypoxia-inducedpulmonaryvascularremodelingrequiresrecruitmentofcirculatingmesenchymalprecursorsofamonocyte/macrophagelineage,termedfibrocytes.Usingtwoneonatalanimalmodels(ratsandcalves)ofchronichypoxicpulmonaryhypertension,wedemo...
医源资料库；在线期刊；美国病理学杂志；2006年第168卷第2期 -
TheScurfymutationofFoxP3inthethymusstromaleadstodefectivethymopoiesis
...EtsregulationoftheerbB2promoter.Oncogene.19:6490–6502.Xing,X.,S.C.Wang,W.Xia,Y.Zou,R.Shao,K.Y.Kwong,Z.Yu,S.Zhang,S.Miller,L.Huang,andM.C.Hung.2000.TheetsproteinPEA3suppressesErbB2overexpressionandinhibitstumorigenesis.Nat.Med.6:189–195.Hurst,H.C.2001.UpdateonHER-2asatargetforcancertherapytheERBB...
医源资料库；在线期刊；实验医学杂志；2005年第202卷第8期 -
HighFrequencyofGastricColonizationwithMultipleHelicobacterpyloriStrainsinVenezuelanSubjects
...SImmunol.Med.Microbiol.10:317-323.Marshall,D.G.,D.C.Coleman,D.J.Sullivan,H.Xia,C.A.O‘Morain,andC.J.Smyth.1996.GenomicDNAfingerprintingofclinicalisolatesofHelicobacterpyloriusingshortoligonucleotideprobescontainingrepetitivesequences.J.Appl.Bacteriol.81:509-517.Martinez,A.,C.Gonzalez,F.Kawaguchi,R....
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第6期 -
T-Cell-MediatedDisruptionoftheNeuronalMicrotubuleNetwork
...dscoredusingascalefrom1to5asfollows:0,nodisease;1,limptailand/orhindlimbataxia;2,hindlimbparesis;3,hindlimbparalysis;4,hindandforelimbparalysis;and5,death.Ondays10,15,and30afterinductionofEAE,threemiceweredeeplyanesthetizedandperfusedintracardiallywith0.1mol/Lphosphatebuffer(PB),followedbyaparaforma...
医源资料库；在线期刊；美国病理学杂志；2006年第168卷第9期 -
VascularEndothelialCellCyclicNucleotidePhosphodiesterasesandRegulatedCellMigration:ImplicationsinAngiogenesis
....VEGFreleasedfromtumorcells,macrophages,andotherimmunecellsinresponsetohypoxia(Brownetal.,1997)stimulatesvascularrelaxation(aprerequisiteforendothelialcellstoentertheangiogeniccascade)viaNOproductionbyVECs(GriffioenandMolema,2000),increasesVECpermeability(Zicheetal.,1997;Caoetal.,2001),andincreasese...
医源资料库；在线期刊；分子药理学杂志；2005年第67卷第1期 -
Myeloidprogenitorsdifferentiateintomicrogliaandpromotevascularrepairinamodelofischemicretinopathy
...ularpermeabilityandproliferation,suchtherapiesdonotaddresstheunderlyinghypoxiathatstimulatestheobservedvasculargrowth.Usingamodelofoxygen-inducedretinopathy,wedemonstratethatapopulationofadultBM–derivedmyeloidprogenitorcellsmigratedtoavascularregionsoftheretina,differentiatedintomicroglia,andfacil...
医源资料库；在线期刊；临床研究杂志；2006年第116卷第12期