TheL-typecalciumchannelintheheart:thebeatgoeson
...legeofMedicine,DepartmentofSurgery,Cincinnati,Ohio,USA.AbstractSydneyRingerwouldbeoverwhelmedtodaybytheimplicationsofhissimpleexperimentperformedover120yearsagoshowingthattheheartwouldnotbeatintheabsenceofCa2+.FascinationwiththeroleofCa2+hasproliferatedintoallaspectsofourunderstandingofnormalcardiac...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第12期SOCS-1regulatesIL-15–drivenhomeostaticproliferationofantigen-naiveCD8Tcells,limitingtheirautoimmunepotential
1TheWalterandElizaHallInstituteofMedicalResearch,Parkville,3050Victoria,Australia2DepartmentofImmunology,TheScrippsResearchInstitute,LaJolla,CA920373DepartmentofMicrobiologyandImmunology,UniversityofMelbourne,Parkville,3052Victoria,AustraliaMicethataredeficientinsuppressorofcytokinesignaling–1(SOC...
医源资料库;在线期刊;实验医学杂志;2005年第202卷第8期Identificationofaninterleukin(IL)-25–dependentcellpopulationthatprovidesIL-4,IL-5,andIL-13attheonsetofhelminthexpulsion
...ouncilLaboratoryofMolecularBiology,CambridgeCB22QH,England,UKType2immunity,whichinvolvescoordinatedregulationofinnateandadaptiveimmuneresponses,canprotectagainsthelminthparasiteinfection,butmayleadtoallergyandasthmaafterinappropriateactivation.Wedemonstratethatil25–/–micedisplayinefficientNippos...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第4期被分离组分在柱中的洗脱原理
...Peakheight,h)――峰的最高点至峰底的距离。⊕峰宽(peakwidth,W)--峰两侧拐点处所作两条切线与基线的两个交点间的距离。W=4σ。⊕半峰宽(peakwidthathalf-height,Wh/2)--峰高一半处的峰宽。Wh/2=2.355σ。⊕标准偏差(standarddeviati...
药品天地;专业药学;实验技术;色谱技术;色谱入门徐荣祥博士获2013年GoldenBiatec国际奖
...-在徐博士之前,该奖项的历届得主包括美国前总统乔治-W-布什、俄罗斯总统弗拉基米尔-普京和法国前总统雅克-希拉克洛杉矶2013年10月17日电/美通社/--徐荣祥博士荣获了设在欧洲斯洛伐克的InformalEconomicForum(IEF)经济俱乐部颁发的...
医学教育;科教新闻DevelopmentofOne-Step,Real-Time,QuantitativeReverseTranscriptasePCRAssaysforAbsoluteQuantitationofHumanCoronavirusesOC43and229E
...canceofhumancoronavirusesinmoresevererespiratoryillnesseshasrecentlybeenshowntobehigherthanwaspreviouslyassumed.Rapidandreliablediagnosisofhumancoronavirusinfectionsthereforebecomesindispensableinaroutineclinicalsetting.Inthisstudy,wepresentaverysensitiveandspecificTaqMan-based,real-timequantitative...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第11期AminoAcidsCriticalforSubstrateAffinityofRatOrganicCationTransporter1LinetheSubstrateBindingRegioninaModelDerivedfromtheTertiaryStructu
...G.,D.G.,N.S.,H.K.)andInstituteofPhysiologicalChemistry(T.D.M.),UniversityofWezburg,Wezburg,GermanyAbstractToidentifyfunctionallyrelevantaminoacidsintheratorganiccationtransporter1(rOCT1),18consecutiveaminoacidsinthepresumedfourthtransmembranehelix(TMH)weremutatedandfunctionallycharacterizedafterexpr...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第5期内毒素致急性肺损伤大鼠肺微血管通透性
...清洗固定后测定肺微血管通透性指标:肺湿/干重量比(W/D)、肺泡灌洗液(BALF)蛋白(BALFpro)、肺通透性指数(PPI)、肺微血管通透性指数(PMPI)及肺组织硝基酪氨酸(NT)、髓过氧化物酶(MPO)、丙二醛(MDA)含量,观...
行业资讯;临床快报;心脑血管相关Corticotrophin-releasingfactorreceptorswithintheventromedialhypothalamusregulatehypoglycemia-inducedhormonalcounterregulation
1DepartmentofInternalMedicine,YaleUniversitySchoolofMedicine,NewHaven,Connecticut,USA.2DepartmentofPharmacologyandDepartmentofPhysiologyandNeurosciences,NewJerseyMedicalSchool,Newark,NewJersey,USA.AbstractRecurrentepisodesofhypoglycemiaimpairsympathoadrenalcounterregulatoryresponses(CRRs)toasubseque...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第6期皮肌炎样症状旋毛虫感染1例
...未闻及杂音。肝区压痛,双肾区压痛。 实验室检查:WBC12.9×109/L,RBC4.58×1012/L,WSCR0.059,W-MCR0.437,W-LCR0.504,W-MCC5.6×109/L。谷丙转氨酶173U/L,肌酸激酶2078U/L,肌酸激酶同工酶67U/L,乳酸脱氢酶697U/L,α-羟丁酸脱氢酶611U/L。胸片:...
合作平台;在线期刊;中华实用医药杂志;2004年第4卷第22期;病例报告