HighPrevalenceofCirculatingCD4+CD28–T-CellsinPatientsWithSmallAbdominalAorticAneurysms
...idtissue.JHistochemCytochem.1998;46:1347–1350.TilsonMD,OzsvathKJ,HiroseH,XiaS.AgeneticbasisforautoimmunemanifestationsintheabdominalaorticaneurysmresidesintheMHCclassIIlocusDR-beta-1.AnnNYAcadSci.1996;800:208–215.MartensPB,GoronzyJJ,SchaidD,WeyandCM.ExpansionofunusualCD4+Tcellsinsevererheumatoid...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第7期中国色谱学的近期(1998-1999)发展
...谱,1999,17(2):112-114[3]TANGWan-ying,ZHOUShen-fan,YANGLing-xiao.ChineseJournalofChromatography,1998,16(2):95-99 唐婉莹,周申范,杨凌霄.色谱,1998,16(2):95-99[4]HOUJing-de,FENGJian-yue,LUWen-chu.JournalofInstrumentalAnalysis,1998,17(5):64-65 ...
药品天地;专业药学;实验技术;色谱技术;色谱论文ApigeninInhibitsExpressionofVascularEndothelialGrowthFactorandAngiogenesisinHumanLungCancerCells:ImplicationofChemopreventionofLungCancer
...ion,wefoundthatapigenininhibitedVEGFtranscriptionalactivationthroughthehypoxia-induciblefactor1(HIF-1)bindingsiteandspecificallydecreasedHIF-1butnotHIF-1subunitexpressioninthecells.InoureffortstounderstandthesignalingpathwaythatmediatesVEGFtranscriptionalactivation,wefoundthatapigenininhibitedAKTand...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第3期SerotoninIncreasesSusceptibilitytoPulmonaryHypertensioninBMPR2-DeficientMice
...fPAH.6eC8Forexample,treatmentofratswithserotoninpotentiatestheeffectsofhypoxiaonpulmonaryarterialpressure,rightventricularhypertrophyandpulmonaryvascularremodeling.9Morerecently,apolymorphisminthe5-HTtransporter(5-HTT)promoter,whichincreasesexpressionofthe5-HTT,hasbeenassociatedwithIPAH,10althoughth...
医源资料库;在线期刊;循环研究杂志;2006年第96卷第3期VascularEndothelialGrowthFactorLocalizationintheAdult
...ells,mustbewithin100µmofabloodvessel.Inresponsetogrowthfactorsandhypoxia,solidtumorsexpresshighlevelsofVEGF,whichisimportantfortheirvascularization.15ManytherapeuticstrategiesaimedatinhibitingVEGFsignalingbyeitherneutralizationofVEGForinhibitionofitsreceptorareunderdevelopmentandinclinicaltria...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第2期InactivationofExtracellularSuperoxideDismutaseContributestotheDevelopmentofHigh-VolumeHypertension
...mentswealsoobservedthatoxonicacidloweredthebloodpressureinhypertensivemice(Xia,unpublishedobservations,2006).Oxonicacidinhibitsuricase,andthusincreasesuratelevelinmice,17,33andurateisknowntoscavengehydroxylradicalsaswellasONOO-.34Despitethelackofselectivityofuricacid,datatosuggestaninvolvementofONOO...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第3期Renaloxidativevulnerabilityduetochangesinmitochondrial-glutathioneandenergyhomeostasisinaratmodelofcalciumoxalateurolithiasis
...maginginsults(4)andhasrecentlybeenshowntobecriticaltocellsurvivalduringhypoxia(23).Clearly,severemitochondrialdisruptionintheformofdiminishedoxygenconsumptionisapparentinthismodel.Inaddition,oxidantstress,whichresultsinanincreasedoxidized/reducedglutathioneratioandisaccompaniedbyproteinsulfhydryloxi...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第10期DefectiveBcelltolerancecheckpointsinsystemiclupuserythematosus
...atedinB-cellautoimmunedisease.Nature.404:995–999.Khare,S.D.,I.Sarosi,X.Z.Xia,S.McCabe,K.Miner,I.Solovyev,N.Hawkins,M.Kelley,D.Chang,G.Van,etal.2000.SevereBcellhyperplasiaandautoimmunediseaseinTALL-1transgenicmice.Proc.Natl.Acad.Sci.USA.97:3370–3375.Lesley,R.,Y.Xu,S.L.Kalled,D.M.Hess,S.R.Schwab,H...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第5期MesangialcellNADPHoxidaseupregulationinhighglucoseisproteinkinaseCdependentandrequiredforcollagenIVexpression
...cnephropathy.GRANTSThisstudywassupportedbytheCanadianDiabetesAssociation.L.XiaissupportedbyapostdoctoralawardfromCanadianInstitutesofHealthResearchNetGroupGrantinGlucoseToxicity.FOOTNOTESThecostsofpublicationofthisarticleweredefrayedinpartbythepaymentofpagecharges.Thearticlemustthereforebeherebymark...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第3期VirulenceGenesandNeutralDNAMarkersofHelicobacterpyloriIsolatesfromDifferentEthnicCommunitiesofWestBengal,India
....185:2927-2935.Pan,Z.J.,D.E.Berg,R.W.vanderHulst,W.W.Su,A.Raudonikiene,S.D.Xiao,J.Dankert,G.N.Tytgat,andA.vanderEnde.1998.PrevalenceofvacuolatingcytotoxinproductionanddistributionofdistinctvacAallelesinHelicobacterpylorifromChina.J.Infect.Dis.178:220-226.Parsonnet,J.1995.IncidenceofHelicobacterpylor...
医源资料库;在线期刊;微生物临床杂志;2003年第41卷第8期