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同种移植激活的宿主树突状细胞能介导免疫耐受*
...lerancewithallograft-activatedhostdendriticcellsXUQi-qi，LIMei，WANGSong-xia,etal.DepartmentofImmunology，PekingUniversityHealthScienceCenter，Beijing100083,China【Abstract】ObjectiveThenegativethymicselectioniscriticalforthematurationofbonemarrowderivedcellstoTcells.Negativeselectionoccursint...
医源资料库；在线期刊；中华医学研究杂志；2006年第6卷第6期 -
InhibitionofT-TypeCalciumChannelsProtectsNeuronsfromDelayedIschemia-InducedDamage
...tiveglutamatereceptorsmarkedlyreducestheriseinintracellularcalciumduringanoxia(SilverandErecinska,1990)andhasbeenshowntobeneuroprotectiveinneuronalcellcultures(Choi,1988)andinanimalmodelsoffocalbrainischemia,hypoglycemia,andtrauma(Albersetal.,1989)butnotinanimalmodelsoftransientglobalischemia(Buchan...
医源资料库；在线期刊；分子药理学杂志；2006年第68卷第1期 -
EarlySignsofAtherosclerosisinObstructiveSleepApnea
...ousexperimentalstudiesdemonstratedtheeffectsofintermittentandcontinuoushypoxiaontheaorticwallinrabbits(49eC51).Neitherintermittentnorcontinuoushypoxiainducedgrossormicroscopicalterationsintheaorta.However,significantreductionsintheamountofglycosaminoglycansandcollagenwereobserved,directlyinfluencing...
医源资料库；在线期刊；美国呼吸和危急护理医学；2005年第171卷第9期 -
CarbonMonoxideProtectsAgainstCardiacIschemia—ReperfusionInjuryInVivoviaMAPKandAkt—eNOSPathways
...actor(TNF)-intheheart;however,250ppm,500ppmofCO,orlowbarometricpressurehypoxia(0.5atm)didnotaffectthem.Exposureto1000ppmCOresultedintheactivationofp38mitogen-activatedproteinkinase(p38MAPK),proteinkinaseB(Akt),endothelialnitricoxidesynthase(eNOS),andcyclicguanosinemonophosphate(cGMP)inthemyocardium....
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第10期 -
RetrospectiveAnalysisofCoagulationFactorIIReceptor(F2R)SequenceVariationandCoronaryHeartDiseaseinHypertensivePatients
...nHUVECstransfectedwithvectorscarrying-506Dand-506Isequencesandexposedtohypoxia.Presenceofthe-506Isequencewasassociatedwitha26%reductionofaffinitybindingtonuclearproteinsandtobluntedF2R-Ainresponsetohypoxiaascomparedwiththe-506Dsequence(allP0.05).Conclusions-F2Rgeneticvariantsmayinfluencethenaturalhi...
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第5期 -
InhibitionofRho-KinaseAttenuatesHypoxia-InducedAngiogenesisinthePulmonaryCirculation
...edincreaseinresistance.Usingquantitativestereology,wenowshowthatchronichypoxiacausedPHandremodelingofthebloodvesselwallsinratsbutthatthisremodelingdidnotleadtostructuralnarrowingofthevascularlumen.SustainedinhibitionoftheRhoA/Rho-kinasepathwaythroughouttheperiodofhypoxicexposureattenuatedPHandpreven...
医源资料库；在线期刊；循环研究杂志；2005年第95卷第7期 -
一期病灶清除植骨内固定治疗原发性椎间隙感染
...tmentofspontaneousinfectionofintervertebralspace∥TANGHuan-zhang,XUHao,YAOXiao-dong,etal.DepartmentofOrthopaedicSurgery,FuzhouGeneralHospitalofNanjingMilitaryCommand,Fuzhou350025ChinaAbstract:［Objective］Toevaluatetheoutcomeonpatientswithprimaryinfectionofintervertebralspaceofthethoracolumbarspi...
医源资料库；在线期刊；中国矫形外科杂志；2008年第16卷第13期 -
Hypoxia-InducedMediatorsofStem/ProgenitorCellTraffickingAreIncreasedinChildrenWithHemangioma
...omchildrenwithproliferatinginfantilehemangioma.Invitro,thecombinationofhypoxiaandestrogendemonstratedasynergisticeffectonhemangiomaendothelialcellproliferation.Conclusions—Thesefindingsdemonstratethatproliferatinghemangiomasexpressknownmediatorsofvasculogenesisandsuggestthatthisprocessmayplaya...
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第12期 -
SildenafilInhibitsAltitude-inducedHypoxemiaandPulmonaryHypertension
...decreaseinexerciseperformance.KeyWords:cardiacoutputexercisegasexchangehypoxiaExposuretohighaltitudeleadstohypoxemia,whichinducesseveralphysiologicorpathophysiologicresponsesinnormalhumans.Amongthose,thehypoxicpulmonaryvasoconstrictionleadstoanincreaseinpulmonaryarterypressure(Ppa),whichmayhaveadver...
医源资料库；在线期刊；美国呼吸和危急护理医学；2005年第171卷第2期 -
AML-M5b外周血T细胞TCRVβ亚家族表达及克隆性增殖特点
...frominitiallydiagnosedleukemicpatients(AML-M5b). ZHANGYu-ping,WANGCai-xia,XUYan-li,etal. (GuangzhouMunicipalFirstPeople’sHospital,Guangzhou510180,Guangdong,P.R.China) Abstract：ObjectiveToinvestigatethedistributionandclonalityofreceptor(TCR)VβrepertoireoftheT-cellsininitia...
医源资料库；在线期刊；中国热带医学杂志；2007年第7卷第10期