MRI图像的边缘检测及特定区域灰度值的跟踪显示方法
...ndles)I=imread(′D:\sccj\F.BMP′);subplot(2,2,1)imshow(I)title(′-′)BW=edge(I,′sobel′)BW1=edge(I,′canny′)subplot(2,2,2)imshow(BW)title(′±β21′)subplot(2,2,3)imshow(BW1)title(′±...
医源资料库;在线期刊;中华现代影像学杂志;2007年第4卷第1期Anti-CD63antibodiessuppressIgE-dependentallergicreactionsinvitroandinvivo
...)inducessecretionofpreformedallergymediators(degranulation)andsynthesisoflipidmediatorsandcytokines.Degranulationproducesmanysymptomsofimmediate-typeallergicreactionsandismodulatedbyadhesiontosurfacescoatedwithspecificextracellularmatrix(ECM)proteins.Thesignalsinvolvedinthismodulationaremostlyunknow...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第3期户尘螨过敏原双向免疫印迹指纹图谱研究
...inlu,ZhangHongyu,WangJinglan,etal. DepartmentofAllergy,PUMCHospital,CAMSPUMC,Beijing100730. 【Abstract】ObjectiveToexploreDermatophagoidespteronyssinus(D.pteronyssinus)allergensfingerprintˉingwithtwo-dimensional(2D)electrophoresisand2Dimmunoblotting.MethodsD.pteronys...
合作平台;在线期刊;中华现代临床医学杂志;2004年第2卷第9A期InsulinSignalinginArteriesPreventsSmoothMuscleApoptosis
...lcells,11andmonocytes.12Thiseffectismediatedbyphosphatidylinositol3-kinase(PI3K)andthedownstreamsignalAkt/proteinkinaseB(PKB)butdoesnotrequireactivationofmitogen-activatedproteinkinases.13VSMCapoptosisoccursinatheroscleroticlesionsinhumans,rabbits,andpigs,andinthethickenedintimaformedafterpercutaneo...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第4期UltrasoundStimulatesCyclooxygenase-2ExpressionandIncreasesBoneFormationthroughIntegrin,FocalAdhesionKinase,Phosphatidylinositol3-Kinase,andAkt
...tegrin,attenuatedtheUS-inducedCOX-2expression.Phosphatidylinositol3-kinase(PI3K)inhibitors2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran-4-onehydrochloride(LY294002)andwortmanninalsoinhibitedthepotentiatingactionofUS.USstimulationincreasedthephosphorylationoffocaladhesionkinase(FAK),extracellularsignal...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第6期不同术式“个体化”治疗桡骨远端关节内骨折
...用克氏针内固定、外固定支架、“T”形支撑钢板、背侧Pi形钢板及多种固定术式联合等方法。[结果]56例病人术后均获随访,随访时间6~36个月,平均14.6个月。复位质量按Aro等提出的测量方法评定:优35例,良17例,可3例,差1...
医源资料库;在线期刊;中国矫形外科杂志;2008年第16卷第24期复旦大学JBC发表癌症信号研究新发现
...ron也在TAZ蛋白水平调控中发挥了作用,尤其是在对细胞内PI3K信号不同状况做出反应时。GSK3磷酸化TAZ中的N-末端phosphodegron,随后磷酸化的TAZ结合到SCFβ-TrCPE3泛素连接酶的β-TrCP亚基上,从而导致TAZ泛素化和降解。当PI3K处于高水平...
行业资讯;临床快报;肿瘤相关EssentialRoleforClassIIPhosphoinositide3-kinase-IsoforminCa2+-Induced,Rho-andRhoKinase-DependentRegulationofMyosinPhosphataseandContraction
...e-silencingtechnique,allowedustodeterminetheroleofphosphoinositide3-kinase(PI3K)classII-isoform(PI3K-C2)asanovel,Ca2+-dependentregulatorofmyosinlight-chainphosphatase(MLCP)andcontraction.TheCa2+-ionophoreionomycininducedarobustcontractileresponsewithanincreaseintheintracellularfreeCa2+concentration(...
医源资料库;在线期刊;分子药理学杂志;2007年第69卷第3期AmurinetransgenicmodelfortranscriptionalregulationoftheNa/Pi-IIamajorrenalphosphatecotransporter
【摘要】LevelsofthetypeIIaNa/Pi(Na/Pi-IIa)cotransporter,whichservesastheprincipalmediatorofphosphatereabsorptioninthekidney,canbemodulatedthroughposttranscriptionalorposttranslationalmechanismsbydietary,hormonal,andpharmacologicalinfluences.Previousstudieshavenotdemonstratedclear-cutevidenceform...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第5期RegulationofEndogenousReactiveOxygenSpeciesinPlateletsCanReverseAggregation
...greversibilityoftheaggregationprocess.Inhibitionofphosphoinositide3-kinase(PI3-kinase)hasbeenshowntocauseplateletdisaggregation.Inaddition,NOisaknownpotentinhibitorofplateletfunction.Inthisstudy,theroleofPI3-kinaseintheregulationofendogenousplateletNOandtherelevancetoplateletfunctionwasdetermined.Me...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第1期