Theplasminogenactivatorsystemmodulatessympatheticnervefunction
...lation.Sympatheticnerveswerestimulatedbyelectricalfieldstimulation(EFS;0–64Hz,supramaximalvoltage;stimulationdurationof15sat5-minintervals,withpulseslasting1mseach).WefirstascertainedthatthetypicalbiphasiccontractileresponsetoEFS(i.e.,purinergicandadrenergicphases)wascompletelyblockedby10μMoftheP...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第9期IsolationandMolecularCharacterizationofStaphylococcussciuriintheHospitalEnvironment
...enicspacerlengthpolymorphismidentifiedthestrainsatthesubspecieslevel,and74(64.3%)strainsofS.sciurisubsp.sciuri,37(32.2%)strainsofS.sciurisubsp.rodentium,and4(3.5%)strainsofS.sciurisubsp.carnaticuswereestablished.Pulsed-fieldgelelectrophoresis(PFGE)analysisshowed21distinctpulsotypes,including17mainty...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第6期VirulenceGenesandNeutralDNAMarkersofHelicobacterpyloriIsolatesfromDifferentEthnicCommunitiesofWestBengal,India
...reparedBHIagarcontainingvariousconcentrationsofMTZ(0,0.2,0.5,1.5,3,8,16,32,64,and128µg/ml)(essentiallyasdescribedinreference22).ThesusceptibilitiesofstrainstoMTZaredescribedhereintermsofMIC,definedoperationallyasthelowestoftheMTZconcentrationslistedabovethatreducestheefficiencyofcolonyformatio...
医源资料库;在线期刊;微生物临床杂志;2003年第41卷第8期Mycobacterialcatalase–peroxidaseisatissueantigenandtargetoftheadaptiveimmuneresponseinsystemicsarcoidosis
...eraofsarcoidosispatientsin9of12(75%)sarcoidosistissues(150–160,80,or60–64kD)butonly3of22(14%)controltissues(all62–64kD;P=0.0006).Matrix-assistedlaserdesorption/ionizationtimeofflightmassspectrometryidentifiedMycobacteriumtuberculosiscatalase–peroxidase(mKatG)asoneofthesetissueantigens.Protei...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第5期如何让肿瘤免疫治疗更多癌症患者?科学家呼吁抗癌药物测试新方法
...能是近年来最大的医学进步之一,它能将病人从鬼门关上拉回来,延长数年的寿命。但事实是,这种情况只会发生在一小部分病人身上。现在,医生说,开发一项能提前鉴定出哪些病人能受益的检测是当务之急,它能省去其他病...
行业资讯;临床快报;肿瘤相关InVitroSusceptibilitiesofClinicalIsolatesofCandidaSpecies,Cryptococcusneoformans,andAspergillusSpeciestoItraconazole:GlobalSurveyof9,359Is
...l.Overall,94%ofallisolatesofC.krusei(thoseforwhichfluconazoleMICswereeither64or64μg/ml)weresusceptibletoitraconazoleatconcentrationsof1μg/ml(Table1).ItraconazolewaslessactiveagainstC.neoformans(Table1).Although80%oftheisolatestestedwereinhibitedby1μgofitraconazoleperml,thepoorpenetrationofitracon...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第8期慢性气道阻塞患者出院后肺康复时间长短及其临床效果
...所作的评估。他们对25个出院病人(平均年龄,65±9岁;FEV1,64±12%预计值)做了全面的PR评价:环肌力机测试的最大负荷量(W-max),用半定量方法(BorgScale)描述呼吸困难程度,6分钟步行距离(6MWD),用圣•乔治呼吸调查问卷(SGRQ)...
行业资讯;临床快报;康复医学InVitroActivitiesofAnidulafunginagainstMorethan2,500ClinicalIsolatesofCandidaspp.,Including315IsolatesResistanttoFluconazole
...ideanevaluationofanidulafunginactivityagainst315isolateswithresistance(MIC,64μg/ml)tofluconazole.Becausethereissomecontroversyovertheoptimalmethodforperforminginvitrosusceptibilitytestingoftheechinocandins(3),thereiscurrentlynostandardizedmethodfortestingtheseagentsagainstCandida.Wehaveelectedtouse...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第11期SynergybetweenaplasminogencascadeandMMP-9inautoimmunedisease
...estoresBPinPlg–/–mice.(A)Pathogenicanti-mBP180IgG(R530,i.d.injection,2.64mg/gbodyweight)inducedsubepidermalblisteringinneonatalPlg–/–micereconstitutedwithmousePlg(5μg/gbodyweight)(B)andactMMP-9(2.5μg/gbodyweight)(D)butnotproMMP-9(2.5μg/gbodyweight)(C)andPBScontrol(A).(E–H)Plgreconstitut...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第4期UseoftheMGBEclipseSystemandSmartCyclerPCRforDifferentiationofMycobacteriumchelonaeandM.abscessus
...artial16SrRNAgenesequencing(26isolatesoftheM.chelonae-M.abscessuscomplexand64remainingisolates,includingMycobacteriumspecies,Nocardiaspecies,andotheraerobicactinomycetes)showed100%specificityandsensitivity.TheITSPCRassayisaccurateandspecific,easytoperform,andagoodsupplementaltestwhenusingpartial16Sr...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第8期