TLRsandNODsmRNAexpressionpatterninhealthymouseeye
...ndeAyalas/n,México,DF,11340,México;jccancinodiaz@hotmail.comAcceptedforpublication1December2004ABSTRACTAims:TolookforTLRandNODmRNAexpressioninthehealthyeyeandinotherimmuneprivilegedandnon-immuneprivilegedmouseorgans.Methods:SemiquantitativeRT-PCRwasperformedtolookforTLR1–9andNOD1andNOD2mRNAexpre...
医源资料库;在线期刊;英国眼科学杂志;2005年第89卷第7期CriticalfunctionofBmx/Etkinischemia-mediatedarteriogenesisandangiogenesis
...ntation,YaleUniversitySchoolofMedicine,NewHaven,Connecticut,USA.2SchoolofPublicHealth,and3ZhongshanOphthalmicCenter,SunYat-SenUniversity,Guangzhou,People’sRepublicofChina.4MolecularandCancerBiologyProgramandLudwigInstituteforCancerResearch,HaartmanInstitute,BiomedicumHelsinkiandHelsinkiUniversityH...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第9期TheRoleofNicotinamideAdenineDinucleotidePhosphateOxidase-DerivedReactiveOxygenSpeciesintheAcquisitionofMetastaticAbilityofTumorCells
...intumorcellacquisitionofmetastaticphenotypebycomparinggp91phoxC/CmiceandC57BL/6Jwild-type(WT)mice.Thegp91phoxC/Cmouseisdeficientinthegp91phoxgene,anessentialsubunitofthephagocytenicotinamideadeninedinucleotidephosphateoxidasethatgeneratessuperoxideanion.QR-32fibrosarcomacellsarenonmetastaticbutareco...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第7期RoleofNaturallyOccurringCD4+CD25+RegulatoryTCellsinExperimentalAtherosclerosis
...lybetweenagedandyoungapolipoproteinE-knockout(ApoE-KO)miceandage-matchedC57BL/6littermates.TheeffectofoxidizedLDL(oxLDL)wastestedonthefunctionalsuppressivepropertiesofTregsfromApoE-KOandC57BL/6mice.Tregs,CD4+CD25-cells,andsalinewereinfusedintoApoE-KOmicetostudytheireffectsonatherogenesis.Tregnumbers...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期BL型麻风误诊分析1例
BL型麻风病是皮肤科比较常见的疾病之一,由于其临床表现较复杂,特异性症状轻微,发病隐匿,极易误诊。笔者就BL型麻风长期误诊为风湿性关节炎1例,报告分析如下。1临床资料1.1病例资料患者,女,50岁,农民。四肢远端麻...
医源资料库;在线期刊;中华现代皮肤科学杂志;2004年第1卷第1期EffectsofangiotensinIIontheCO2dependenceofHCO3
...rstusedequilibrated5%CO2/22mMHCO3/pH7.40inbathandlumen.At1011M,basolateral(BL)ANGIIincreasedJHCO3by41%,andluminalANGIIincreasedJHCO3by35%.At109M,basolateralANGIIdecreasedJHCO3by43%,whereasluminalANGIIwaswithouteffect.Second,wevaried[CO2]BLfrom0to20%atfixed[HCO3]BLandpHBL.Fractionalstimulationproduce...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第2期ThecomplementinhibitoryproteinDAF(CD55)suppressesTcellimmunityinvivo
...anchoredmembraneinhibitorofcomplementwithbroadclinicalrelevance.Here,weestablishanadditionalandunexpectedroleforDAFinthesuppressionofadaptiveimmuneresponsesinvivo.InbothC57BL/6andBALB/cmice,deficiencyoftheDaf1gene,whichencodesthemurinehomologueofhumanDAF,significantlyenhancedTcellresponsestoactiveim...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第4期InvolvementofNeuronalCannabinoidReceptorCB1inRegulationofBoneMassandBoneRemodeling
...D1CB1-/-mice).Bycontrast,ourpreliminarystudiesincb1-/-mice,backcrossedtoC57BL/6Jmice(C57CB1-/-mice),revealedlowbonemass(LBM).WethereforeanalyzedCB1expressioninboneandcomparedtheskeletonsofsexuallymatureC57CB1-/-andCD1CB1-/-miceinthesameexperimentalsetting.CB1mRNAisweaklyexpressedinosteoclastsandimmu...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第9期小鼠常用近交系
...,雌鼠为816天。平均体重252日龄雄鼠为30g,雌鼠为28g。C57BL小鼠基因型为aaBBCC。毛色为黑色。C57BL小鼠对Graffi白血病因子较敏感。对麻疹病毒敏感。乳腺肿瘤发生率低。网状组织肿瘤自发率,雌鼠少于10﹪,雄鼠为4﹪。较老的动...
医药经济;生物技术;实验技术;动物学技术四、近交系小鼠和大鼠中自发性肿瘤的发病率
...88%。RⅢ/An育成雌鼠49%。 CC57BR、CC57W、TM、TSI、IF、C57BL等品系小鼠中基本没有乳腺癌或不发生自发性乳腺肿瘤。BALB/C雌鼠3%,但投给乳癌因子后升高。C57BL/6J生产雌鼠1%。C57BL/CdJ、C57L、L、MAS/A、NZO、XLⅡ小鼠自发乳腺癌低。 ...
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