NewinsightsonhumanTcelldevelopmentbyquantitativeTcellreceptorgenerearrangementstudiesandgeneexpressionprofiling
...regulationofTcellreceptor(TCR)generearrangementduringhumanTcelldevelopment,weanalyzedTCRgenerearrangementsbyquantitativePCRanalysisinnineconsecutiveTcelldevelopmentalstages,includingCD34+lin–cordbloodcellsasareference.ThesamestageswereusedforgeneexpressionprofilingusingDNAmicroarrays.WeshowthatTCR...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第11期PreventionofUVradiation–inducedimmunosuppressionbyIL-12isdependentonDNArepair
1LudwigBoltzmannInstituteforCellBiologyandImmunobiologyoftheSkin,DepartmentofDermatology,UniversityMünster,D-48149Münster,Germany2NationalInstituteofPublicHealthandtheEnvironment,LaboratoryofHealthEffectsResearch,3720Bilthoven,Netherlands3DepartmentofDermatology,UniversityKiel,D-24105Kiel,GermanyT...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第2期土壤淋溶柱色谱中有机调节剂对保留的影响
...(25.0±0.1)℃,用UV检测器在线检测。实验表明,logk′=logk′w+aφ+bφ2和logk′=logk′w-Sφ两式均可以用来描述保留规律,但后者因其计算简单、实验数据点不需太多,可更好地满足实验要求。还解释了同系列的同系物(甲基苯类、正...
药品天地;专业药学;实验技术;色谱技术;色谱分析实例糖尿病大鼠逼尿肌线粒体超微结构及基质的改变
...yofultrastructuralchangeofmitochondrionofdetrusorindiabetesrats ShuangWeibing,WangDongwen,ZhangWeifang,WuBowei (DepartmentofUrology,FirstHospitalofShanxiMedicalUniversity,Taiyuan030001,China) ABSTRACT:ObjectiveToobservetheultrastructuralchangesofdetrusorinexperimentalT2DMrats.Methods1...
医源资料库;在线期刊;现代泌尿外科杂志;2006年第10卷第1期AID-dependenthistoneacetylationisdetectedinimmunoglobulinSregions
...gyandImmunology,UniversityofIllinoisCollegeofMedicine,Chicago,IL60612Classswitchrecombination(CSR)isregulatedbytheexpressionofactivation-induceddeaminase(AID)andgermlinetranscripts(GLTs).AID-dependentdouble-strandbreaks(DSBs)areintroducedintoswitch(S)regionsandstimulateCSR.Althoughhistoneacetylation...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第1期ProductionofHerpesBVirusRecombinantGlycoproteinsandEvaluationofTheirDiagnosticPotential
...ponsesisthemethodofchoicefortherapididentificationofBvirus-infectedanimals.WeevaluatedthediagnosticpotentialofrecombinantBvirusglycoproteinsforthedetectionofimmunoglobulinG(IgG)antibodiesinmonkeyandhumansera.GlycoproteinsB,C,andEandsecreted(sgG)andmembrane-associated(mgG)segmentsofglycoproteinG(gG)w...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第2期AssessmentofRibosomalLarge-SubunitD1-D2,InternalTranscribedSpacer1,andInternalTranscribedSpacer2RegionsasTargetsforMolecularIdentification
...DiseaseControlandPrevention,Atlanta,GeorgiaABSTRACTMolecularapproachesarenowbeingdevelopedtoprovideamorerapidandobjectiveidentificationoffungicomparedtotraditionalphenotypicmethods.Ribosomaltargets,especiallythelarge-subunitRNAgene(D1-D2region)andinternaltranscribedspacers1and2(ITS1andITS2regions),h...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第5期土壤淋溶柱色谱中有机调节剂对保留的影响
...(25.0±0.1)℃,用UV检测器在线检测。实验表明,logk′=logk′w+aφ+bφ2和logk′=logk′w-Sφ两式均可以用来描述保留规律,但后者因其计算简单、实验数据点不需太多,可更好地满足实验要求。还解释了同系列的同系物(甲基苯类、正...
药品天地;专业药学;实验技术;色谱技术;色谱论文Mannanbindinglectinasanadjuncttoriskassessmentformyocardialinfarctioninindividualswithenhancedrisk
...clearanceofinflammatoryagents,butthepredictivevalueofMBLlevelsforMIisnotknown.MBLwasanalyzedinsubgroupsofthepopulation-basedReykjavikstudy,acohortof19,381participantsrecruitedfrom1967.MBLlevelswereverystableovertime(selfcorrelation:0.86).Inacross-sectionalgroupfromtheoriginalcohort(n=987),highMBL(1,...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第1期PU.1regulatesthecommitmentofadulthematopoieticprogenitorsandrestrictsgranulopoiesis
TheWalterandElizaHallInstituteofMedicalResearch,Parkville,Victoria3050,AustraliaAlthoughthetranscriptionfactorPU.1isessentialforfetallymphomyelopoiesis,weunexpectedlyfoundthateliminationofthegeneinadultmicealloweddisturbedhematopoiesis,dominatedbygranulocyteproduction.Impairedproductionoflymphocytes...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第9期