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LossofC/EBPcellcyclecontrolincreasesmyeloidprogenitorproliferationandtransformstheneutrophilgranulocytelineage
...icResearchCenterforStemCellBiologyandCellTherapy,LundUniversity,22184Lund,Sweden4EMBLMouseBiologyUnit,00016Monterotondo,ItalyCCAAT/enhancerbindingprotein(C/EBP)isamyeloid-specifictranscriptionfactorthatcoupleslineagecommitmenttoterminaldifferentiationandcellcyclearrest,andisfoundmutatedin9%ofpatient...
医源资料库；在线期刊；实验医学杂志；2005年第202卷第1期 -
ImpaireddegranulationbutenhancedcytokineproductionafterFcRIstimulationofdiacylglycerolkinase–deficientmastcells
...rol-dependentsignalingthatactsbyconvertingdiacylglyceroltophosphatidicacid.WereportedpreviouslythatDGK–/–micehaveenhancedinvivoTcellfunction.Here,wedemonstratethatthesemicehavediminishedinvivomastcellfunction,asrevealedbyimpairedlocalanaphylacticresponses.Concordantly,DGK–/–bonemarrow–deri...
医源资料库；在线期刊；实验医学杂志；2006年第203卷第6期 -
MutationalescapefromCD8+Tcellimmunity:HCVevolution,fromchimpanzeestoman
aD.G.B.andC.M.W.areatCenterforVaccinesandImmunity,ColumbusChildren‘sResearchInstitute,Columbus,OH43205.bC.M.W.isatCollegeofMedicineandPublicHealth,OhioStateUniversity,Columbus,OH43210.ThemechanismsbywhichthehepatitisCvirus(HCV)establishespersistencearenotyetfullyunderstood.Previouschimpanzeeandnow...
医源资料库；在线期刊；实验医学杂志；2005年第201卷第11期 -
P.Amavisit,W.Boonyawiwat,andA.Bangtrakulnont
...MedicalSciences,MinistryofPublicHealth,Nonthaburi,ThailandABSTRACTDuplexPCRwasdevelopedtoscreenSalmonellaentericaserovarTyphimuriumphagetypeDT104andrelatedstrainsinThailandbecauseaphagetypinglaboratoryofserovarTyphimuriumisnotavailable.Of46isolatesofserovarTyphimuriumand32isolatesofS.entericaserovar...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第6期 -
配合光疗法促进压疮高危患者创面愈合
...照射面积直径3cm。非接触法照射，Ⅰ度损伤:输出功率250mW，功率密度0.035W/cm2;Ⅱ度以上损伤:输出功率300mW，功率密度0.042W/cm2，每区照射5min，较大创面分2～3区照射。（2）紫外线照射:辐射光谱为80%的254nm短波紫外线。在激光照射...
资料库；在线期刊；中华现代护理学杂志；2005年第2卷第7期 -
ArylHydrocarbonReceptorSpliceVariantsintheDioxin-ResistantRat:TissueExpressionandTransactivationalActivity
...drug-metabolizingenzymesandmediatoroftoxicityofdioxin-likechemicals.TheHan/Wistar(Kuopio)ratstrain(H/W)isremarkablyresistanttolethaleffectsof2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD)becauseofapointmutationintheexon/intron10boundaryinAHRgenomicstructurethatleadstouseof3alternativecrypticsplicesites,p...
医源资料库；在线期刊；分子药理学杂志；2007年第69卷第10期 -
38.7营养素的需要量
...BasalEnergyExpenditure,BEE）的公式如下： 男性BEEkc=66.5+13.8W+5H-6.8A 女性BEEkc=65.1+9.6W+1.9H-4.7A 婴儿BEEkc=22.1+31.1W+1.2H 其中W=体重kg、H=身长cm、A=年龄、kc=kcal。在此基础上，再根据活动量，疾病消耗或同化效率的差异，增加额...
医源资料库；医源图书馆；教材类；临床营养学 -
GenotypingofMadurellamycetomatisbySelectiveAmplificationofRestrictionFragments(AmplifiedFragmentLengthPolymorphism)andSubtypeCorrelationwith
...alCenterRotterdam,DepartmentofMedicalMicrobiologyInfectiousDiseases,Dr.Molewaterplein40,3015GDRotterdam,TheNetherlandsKeygeneN.V.,DepartmentofMicrobialGenomics,AgroBusinesspark90,6708PWWageningen,TheNetherlandsPathoFinderBV,Canisius-WilhelminaHospital,WegdoorJonkerbos100,6532SZNijmegen,TheNetherland...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第9期 -
ViciousandVirtuousCirclesintheDynamicsofInfectiousDiseaseandtheProvisionofHealthCare:GonorrheainBritainasanExample
...vicestoprovideappropriateandtimelycareisreduced.Toexploretherelationshipbetweencapacityanddemandforcare,wedevelopedandanalyzedamathematicalmodelofgonorrheatransmission,incorporatingpatientflowthroughtreatmentservicesandheterogeneityinsexualriskbehavior.Twoequilibriumlevelsofinfectionincidence“high...
医源资料库；在线期刊；传染病学杂志；2005年第191卷第17期 -
慢性气道阻塞患者出院后肺康复时间长短及其临床效果
...2%预计值)做了全面的PR评价:环肌力机测试的最大负荷量（W-max）,用半定量方法（BorgScale）描述呼吸困难程度,6分钟步行距离（6MWD）,用圣•乔治呼吸调查问卷（SGRQ）评估的生活质量。所有指标均评定3次：研究初，10个时间段后...
行业资讯；临床快报；康复医学