UltrasoundStimulatesCyclooxygenase-2ExpressionandIncreasesBoneFormationthroughIntegrin,FocalAdhesionKinase,Phosphatidylinositol3-Kinase,andAkt
...tegrin,attenuatedtheUS-inducedCOX-2expression.Phosphatidylinositol3-kinase(PI3K)inhibitors2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran-4-onehydrochloride(LY294002)andwortmanninalsoinhibitedthepotentiatingactionofUS.USstimulationincreasedthephosphorylationoffocaladhesionkinase(FAK),extracellularsignal...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第6期HighGlucoseInducesHumanEndothelialCellApoptosisThroughaPhosphoinositide3-Kinase–RegulatedCyclooxygenase-2Pathway
...ersity,Taipei;andtheDepartmentofInternalMedicine(F.M.H.),Tao-YuanGeneralHospital,Taoyan,Taiwan.CorrespondencetoShing-HwaLiu,PhD,InstituteofToxicology,CollegeofMedicine,NationalTaiwanUniversity,No.1,Section1,Jen-AiRd,Taipei,10043,Taiwan.E-mailshliu@ha.mc.ntu.edu.twAbstractObjectives—Diabetesmellitu...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第3期Y染色体消亡女科学家找到原因
...性染色体变化的机制。KaterynaD.Makova目前任首席研究员(PI),她主持的实验室主要研究DNA突变,染色体变异等课题。在这次的研究中,KaterynaD.Makova发现由于不断的进化,保持高度的进化效率男性的Y染色体的变异率很高,而女性...
行业资讯;临床快报;遗传与基因组莲房原花青素诱导人口腔表皮样癌细胞凋亡作用
...胞库),莲房原花青素LSPC(本实验室制备,含量98%),PI(上海长征医院提供),FITC-annexinⅤ(bendermedsystems,Austria)。二氧化碳培养箱(Galaxy,StephenClarkFabricationsLtd,英国),EPICS-XL流式细胞仪(美国Coulter公司),JEM-1200透射...
合作平台;在线期刊;中华实用医药杂志;2004年第4卷第22期;论著脑震荡97例TCD分析
...纤维释放血管活性肽,引起神经源性炎症,造成血浆蛋白渗出及血管扩张[3]。尽管CT在诊断颅脑损伤的价值不容置疑,但TCD能提供CT不能反映的伤后脑血流的变化情况,尤其是对CT阴性的患者,TCD提供的血流变化是临床诊治必...
医源资料库;在线期刊;中华现代外科学杂志;2006年第3卷第6期PredictorsofHIVDrug-ResistanceMutationsinaLargeAntiretroviral-NaiveCohortInitiatingTripleAntiretroviralTherapy
...ishColumbia,Canada.Methods.Allplasmasampleswithplasmavirusloads(pVLs)1000copies/mLcollectedduringthefirst30monthsoffollow-upweregenotypedfordrugresistance.Theprimaryoutcomemeasurewastimetothefirstdetectionofmajordrug-resistancemutation(s).Coxproportionalhazardregressionwasusedtoidentifyfactorssignif...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第3期医学属性特征敏感性问题的调查设计与分析
... Thedesignandanalysisonqualitativesensitiveproblem WangChunping,GuoJizhi,ZhaiQiang WeifangMedicalCollege,Shandong261041. 【Abstract】ObjectiveToresearchthedesignandanalysisonqualitativesensitiveproblem.MethodsAim-ingatdifferenttypesofqualitativesensitiveproblem,th...
合作平台;在线期刊;中华医学研究杂志;2004年第4卷第12期;论著ClinicalandMolecularAnalysisofExtended-Spectrum-Lactamase-ProducingEnterobacteriaintheCommunitySetting
...Pharmacie,UniversitedeBordeaux2,Bordeaux,FranceLaboratoiredeBacteriologie,HpitalHaut-Levêque,Pessac,FranceLaboratoiresd‘AnalysesMedicalesduReseauAquitaine,Bordeaux,FranceABSTRACTDuringaprevioussurvey,fiveextended-spectrum-lactamase(ESBL)-producingenterobacteria(ESBLE)(twoEnterobacteraerogenesisol...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第10期Centralcontrolofrenalsodium-phosphate(NaPi-2)transporters
【摘要】Regulationofphosphate(Pi)reabsorptionoccursthroughtheup-anddownregulationoftherenaltype-IIsodiumPicotransporters(NaPi-2).Recently,renalNaPi2-typeexpressionhasbeenidentifiedinareasofthebrain.ThepresentstudydeterminedwhetherbrainNaPi-2isregulatedbydietaryPiandwhetherthebehavioralandrenalad...
医源资料库;在线期刊;美国生理学杂志;2004年第287卷第4期PI3K-AktPathwaySuppressesCoagulationandInflammationinEndotoxemicMice
...issuefactor(TF).Inthisstudy,weanalyzedtheroleofthephosphoinositide3-kinase(PI3K)-Aktpathwayintheactivationofcoagulationandtheinnateimmuneresponseinamousemodelofendotoxemia.MethodsandResults—WortmanninandLY294002wereusedtoinhibitthePI3K-Aktpathway.WefoundthatwortmannininhibitedLPS-inducedAktphospho...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第10期