TACIandBAFF-RmediateisotypeswitchinginBcells
...RincludeexpressionofGLTs,expressionofthegeneforactivation-induceddeaminase(AID),followedbydeletionalswitchrecombinationandexpressionofIμ-CHtranscripts.APRILandBAFFinduced1GLTandGLT,butnodetectableGLT,innegativelysortedBcellsfromCD40–/–mice(Fig.1C).APRIL,andtoalesserextent,BAFFinducedAIDgeneexpr...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第1期EvidenceforPreferentialGenotypingofaMinorityHumanImmunodeficiencyVirusPopulationDuetoPrimer-TemplateMismatchingduringPCR-BasedAmplification
...edonplasmagenotypicantiretroviralresistancetestinginpatientsfailingtherapy.AIDS14:F83-F93.Christopherson,C.,J.Sninsky,andS.Kwok.1997.Theeffectsofinternalprimer-templatemismatchesonRT-PCR:HIV-1modelstudies.NucleicAcidsRes.25:654-658.Cingolani,A.,A.Antinori,M.G.Rizzo,R.Murri,A.Ammassari,F.Baldini,S.Di...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期艾滋病合并肺结核临床特点分析
...接触12例(60%);临床表现为持续发热(100%),咳嗽、咳痰(70%),明显消瘦(78%),淋巴结肿大(40%),皮肤溃烂(20%),X线表现为血行播散型肺结核(80%),合并淋巴结结核(20%),6个月内病死率60%。PPD试验多为阴性。结...
医源资料库;在线期刊;中华现代中西医杂志;2005年第3卷第22期RateandIncidenceEstimatesofRecentHumanImmunodeficiencyVirusType1InfectionsamongPregnantWomeninSoPaulo,Brazil,from1991to2002
InstitutoAdolfoLutz,SecretariadeEstadodaSaúdeNationalProgramonSTDandAIDS,MinistryofHealth,SoPaulo,BrazilViralandRickettsialDiseaseLaboratory,CaliforniaDepartmentofHealthServices,Berkeley,CaliforniaABSTRACTTheserologicaltestingalgorithmforrecenthumanimmunodeficiencyvirus(HIV)seroconversion(STARHS)wa...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第3期云南沧源县教育工作者预防艾滋病健康教育效果评价
...强化。另外,异物、蚊虫叮咬不会传播艾滋病,咳嗽、吐痰不会传播艾滋病,共用毛巾、泳池、马桶不会传播艾滋病等问题,培训后的知晓率高于培训前,差异有统计学意义。这一结果说明普遍性宣传不能解决艾滋病传播具体情...
医源资料库;在线期刊;中国学校卫生;2007年第27卷第6期MolecularDiversityofHIVinAlbania
...nceofresistancetoantiretroviraldrugsisstilllow.TheepidemicofHIVinfectionandAIDSseemstohavehadalimitedimpactontheBalkancountries,which,withtheexceptionofGreece,areconsideredtobepartofcentralEurope[1].Inrecentyears,mostcountriesinthewesternBalkanshavebeenaffectedbywar,dramaticpoliticalchanges,andsocio...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第15期DiagnosisofCerebralToxoplasmosisinAIDSPatientsinBrazil:ImportanceofMolecularandImmunologicalMethodsUsingPeripheralBloodSamples
...etherlandsABSTRACTCerebraltoxoplasmosisisthemostcommoncerebralfocallesioninAIDSandstillaccountsforhighmorbidityandmortalityinBrazil.ItsoccurrenceismorefrequentinpatientswithlowCD4+T-cellcounts.Itisdirectlyrelatedtotheprevalenceofanti-Toxoplasmagondiiantibodiesinthepopulation.Therefore,itisimportantt...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第10期艾滋病并发肺部感染
...出病原体。呼吸道分泌物涂片检出率甚低,可超声雾化导痰检查。纤支镜灌洗液沉淀病原体检出率约60%-80%,支气管肺泡灌洗液或经纤支镜活检标本阳性率可达90%。必要时,经皮肺穿刺或胸肺活检以明确诊断。标本可用Giemsa...
求医问药;疾病大全;胸部第十节 艾滋病并发肺部感染
...出病原体。呼吸道分泌物涂片检出率甚低,可超声雾化导痰检查。纤支镜灌洗液沉淀病原体检出率约60%-80%,支气管肺泡灌洗液或经纤支镜活检标本阳性率可达90%。必要时,经皮肺穿刺或胸肺活检以明确诊断。标本可用Giemsa...
医源资料库;医源图书馆;教材类;呼吸病学TheinvivopatternofAIDtargetingtoimmunoglobulinswitchregionsdeducedfrommutationspectrainmsh2–/–ung–/–mice
...hintheimmunoglobulinheavychainlocus,catalyzedbyactivation-induceddeaminase(AID).Intheabsenceofuracil-DNAglycosylase(UNG)andthehomologueofbacterialMutS(MSH)–2mismatchrecognitionprotein,theresultantU:GlesionsarenotprocessedintoswitchingeventsbutarefixedbyreplicationallowingsitesofAID-catalyzeddeamin...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第9期