小鼠白细胞介素-12融合蛋白编码基因的构建与表达研究
小鼠白细胞介素-12融合蛋白编码基因的构建与表达研究免疫学杂志2000年第1期第16卷基础免疫学作者:成军 赵鸿 钟彦伟 刘妍 杨继珍 董菁 斯崇文 王勤环单位:成军(解放军302医院传染病研究所基因治疗研究中心,北...
合作平台;医学论文;临床医学与专科论文;检验医学AssessmentofvitaminB-12,folate,andvitaminB-6statusandrelationtosulfuraminoacidmetabolisminneonates
...otalserumhomocysteine(tHcy)hasbeenusedasanindicatorofintracellularvitaminB-12,vitaminB-6,andfolatestatusinadults,butdataforneonatesandinfantsarelacking.VitaminB-12deficiencymayhavefataleffectsonneurologicdevelopmentininfants;therefore,earlydiagnosisiscrucial.Objective:Ouraimwastoprovideareferenceran...
医源资料库;在线期刊;美国临床营养学杂志;2000年72卷第3期HBV感染者血清及PBMC培养上清IL-12水平的检测及意义
...乙型肝炎、HBsAg携带者及正常人血清和PBMC培养上清液中IL-12水平,并探讨其意义。方法应用FicollHypaque密度梯度离心法从肝素化血中分离外周血PBMC,用ELISA方法检测血清及PBMC培养上清液IL-12水平。结果(1)血清IL-12检测结果:急性...
合作平台;在线期刊;中华实用医药杂志;2004年第4卷第1期;其他Homocysteine,vitaminB-12,andfolicacidandtheriskofcognitivedeclineinoldage:theLeiden85-PlusStudy
...TBackground:HighconcentrationsofhomocysteineandlowconcentrationsofvitaminB-12andfolicacidarefrequentlyobservedinsubjectswithdementia.Objective:Weassessedwhetherserumconcentrationsofhomocysteine,vitaminB-12,orfolicacidpredictcognitivedeclineinoldage.Design:Thiswasaprospective,population-based,longitu...
医源资料库;在线期刊;美国临床营养学杂志;2005年82卷第4期Interleukin12InducesT-CellRecruitmentIntotheAtheroscleroticPlaque
...patientswithacutecoronarysyndrome(ACS),spontaneouslyexpressinterleukin(IL)-12receptors,evenintheabsenceofantigenicstimulation.CD4+CD28eCIL-12R+cellsrespondedtoIL-12stimulationwiththeupregulationofthechemokinereceptorCCR5andtheC-typelectinreceptorCD161,bothimplicatedinregulatingtissuehomingofeffector...
医源资料库;在线期刊;循环研究杂志;2006年第96卷第3期DAP12(KARAP)amplifiesinflammationandincreasesmortalityfromendotoxemiaandsepticperitonitis
...hnology,JapanScienceandTechnologyAgency,Honcho4-1-8,Kawaguchi,Saitama332-0012,JapanDAP12(KARAP)isatransmembranesignalingadaptorforafamilyofinnateimmunoreceptorsthathavebeenshowntoactivategranulocytesandmonocytes/macrophages,amplifyingproductionofinflammatorycytokines.Contrastingwiththesedata,recents...
医源资料库;在线期刊;实验医学杂志;2005年第202卷第3期Folicacidfortification:ismaskingofvitaminB-12deficiencywhatweshouldreallyworryabout?
...ndencetoPVerhoef,UnileverFoodandHealthResearchInstitute,OliviervanNoortlaan120,3133ATVlaardingen,Netherlands.Seecorrespondingarticleonpage1187.MandatoryfortificationofflourwithfolicacidhasreducedthenumberofneuraltubedefectsinNorthAmerica(1).ThestudybyWyckoffandGanji(2)inthisissueoftheJournalsuggests...
医源资料库;在线期刊;美国临床营养学杂志;2007年86卷第4期HyperhomocysteinemiaandvitaminB-12deficiencyinelderlyusingTitleIIIcnutritionservices
...prevalenceofhyperhomocysteinemiaintheolderpopulationwithcoexistingvitaminB-12deficiencyisnotknown.Objective:TheobjectivewastodeterminetheprevalenceofhyperhomocysteinemiaandvitaminB-12deficiencyinelderlywhowereusingTitleIIIcnutritionservices,afterfolatefoodfortificationintheUnitedStates.Design:Demogr...
医源资料库;在线期刊;美国临床营养学杂志;2003年77卷第1期12/15LipoxygenaseMediatesMonocyteAdhesiontoAorticEndotheliuminApolipoproteinE-DeficientMiceThroughActivationofRhoAandNF-B
【摘要】Objectives-12/15lipoxygenase(12/15LO)hasbeenimplicatedasamediatorofinflammationandatherosclerosis.Inthecurrentstudy,weidentifiedmechanismsthroughwhich12/15LOmediatesmonocyte:endothelialinteractionsinvivoinapolipoproteinE-deficientmice(apoEKO),awell-characterizedmousemodelofatherosclerosi...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第6期人IL-12的克隆、表达及生物活性的鉴定
人IL-12的克隆、表达及生物活性的鉴定中国免疫学杂志1999年第1期第15卷分子与细胞免疫学作者:曲春枫 孙宗棠单位:中国协和医科大学肿瘤研究所,北京100021关键词:人IL-12;树突状细胞;DNA序列;生物学活性 中国图书分...
合作平台;医学论文;临床医学与专科论文;检验医学