SusceptibilityofFilamentousFungitoVoriconazoleTestedbyTwoMicrodilutionMethods
...nvasivefungalinfection(9,27).Increasedincidenceappearstobelinkedtothegrowinguseofimmunosuppressivedrugsforthetreatmentofautoimmunediseases,tothespreadofAIDS,totheincreasinguseofchemotherapyagainstvarioustumors,andtothelargenumberoftransplantsnowperformed(8,25,27).Manyemergingfungiposeproblemsofintri...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期InTuberculousPleuralEffusions,ActivatedNeutrophilsUndergoApoptosisandAcquireaDendriticCellLikePhenotype
...tion/apoptotis(CD11b,CD64,tumornecrosisfactorreceptor,andFasligand)areup-regulated,togetherwithalossofCD16expression.However,neutrophilsexpressCD86,CD83,andmajorhistocompatibilitycomplexclassIIantigens,acquiringdendriticcell(DC)characteristics.Therefore,thecytokinemilieuinthepleuralspacemayinfluence...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第15期TheHypolipidemicNaturalProductGuggulsteroneIsaPromiscuousSteroidReceptorLigand
...IndianaUniversitySchoolofMedicine,Indianapolis,Indiana(T.P.B.,K.B.)AbstractGuggulsterone(GS)istheactivesubstanceinguggulipid,anextractoftheguggultree,Commiphoramukul,usedtotreatavarietyofdisordersinhumans,includingdyslipidemia,obesity,andinflammation.TheactivityofGShasbeensuggestedtobemediatedbyanta...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第3期CirculatingLeukocyte-DerivedMicroparticlesPredictSubclinicalAtherosclerosisBurdeninAsymptomaticSubjects
...anti-GpIb,anti-CD105oranti-CD11aantibodiesaspreviouslydescribed.21TheprocoagulantphospholipidcontentwasdeterminedbyaprothrombinaseassayandtheamountofMP(MPlevel)wasexpressedasnanomolarphosphatidylserine(PS)equivalent.MPSamplePreparationAllsampleswerepreparedandstoredasfollows.Fivemillilitersof12-hour...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第12期Mildrenalischemia-reperfusionreduceschargeandsizeselectivityoftheglomerularbarrier
...erularbarrierremainunclear.Longerperiodsofwarmischemia(1-2h)inducesevereoliguriaand/oranuria,whicheffectivelyeliminateourpossibilitiestostudytheglomerularbarrier.ThisobstaclewasingeniouslycircumventedbyYoshiokaetal.(35),astheyinfusedhydrogenperoxideintorenalarteriesandfounddose-dependentreversiblepr...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第6期DiminishedReplicativeFitnessofPrimaryHumanImmunodeficiencyVirusType1IsolatesHarboringtheK65RMutation
...eachcompetitionwasquantifiedbyTaqManreal-timePCRasdescribedelsewhere(28).Figure2showsthereplicativefitnessofeachdrug-resistantmutantrelativetoitscorrespondingwild-typevirus.Asobservedintheviralgrowthkinetics,eachdrug-resistantvirusshowedadecreaseinreplicativefitness.Inpatient7101,thevirusobtainedatw...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第3期Small-bowelabsorptionofD-tagatoseandrelatedeffectsoncarbohydratedigestibility:anileostomystudy
...ngkildeandHenrikAndersson1FromtheDepartmentofClinicalNutrition,GöteborgUniversity,Göteborg,Sweden,andtheDepartmentofAnimalNutritionandPhysiology,DanishInstituteofAgriculturalSciences,ResearchCenter,Foulum,Denmark.2SupportedbygrantsfromtheSwedishCancerFoundationandMDFoodIngredientsAmba,Vide...
医源资料库;在线期刊;美国临床营养学杂志;2001年73卷第1期RoleofADPRibosylationFactor1intheAssemblyandSecretionofApoB-100–ContainingLipoproteins
...ofMedicalBiochemistry,WallenbergLaboratoryforCardiovascularResearch,G?teborgUniversity,G?teborg,Sweden.CorrespondencetoSven-OlofOlofsson,TheWallenbergLaboratory,SahlgrenskaUniversityHospital,SE-41345G?teborg,Sweden.E-mailSven-Olof.Olofsson@medkem.gu.seAbstractObjective—WeinvestigatedtheroleofADPri...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第3期Suppressionofnocturnalfattyacidconcentrationsbybedtimecarbohydratesupplementintype2diabetes:effectsoninsulinsensitivity,lipids,andglycemic
...,theDepartmentofInternalMedicine,SahlgrenskaUniversityHospital,GöteborgUniversity,Göteborg,Sweden,andtheDepartmentofMedicine,theUniversityofHelsinki.2SupportedbygrantsfromtheSwedishMedicalResearchCouncil(projectB-3506),theSwedishDiabetesAssociation,theHelsinkiUniversityCentralHospitalFound...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第5期FOXO3a-dependentregulationofPumainresponsetocytokine/growthfactorwithdrawal
...nducedinap53-dependentmanner.However,thetranscriptionfactordrivingPumaup-regulationinresponsetop53-independentapoptoticstimulihasyettobeidentified.Here,weshowthatFOXO3aup-regulatesPumaexpressioninresponsetocytokineorgrowthfactordeprivation.Importantly,dysregulatedAktsignalinginlymphoidcellsattenuate...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第7期