Magnesiumrequirements:newestimationsformenandwomenbycross-sectionalstatisticalanalysesofmetabolicmagnesiumbalancedata
...qualtomagnesiumintake(M)]atmagnesiumintakesof165mg/d[95%predictioninterval(PI):113,237mg/d;Y=19.8+0.880M],2.36mg·kg1·d1(95%PI:1.58,3.38mg·kg1·d1;Y=0.306+0.870M),or0.075mg·kcal1·d1(95%PI:0.05,0.11mg·kcal1·d1;Y=0.0...
医源资料库;在线期刊;美国临床营养学杂志;2006年84卷第4期IntestinalNa-PicotransporteradaptationtodietaryPicontentinvitaminDreceptornullmice
...ntestinalNa+-dependentphosphatetransportadaptationtovariablelevelsofdietaryPi.Therefore,thegoalofthecurrentstudywastoassessNa+-dependentPicotransportactivityintransgenicmicetodeterminewhethervitaminDisanessentialmediatorofthisprocess.Intestinalbrush-bordermembrane(BBM),Na+-dependentPicotransportacti...
医源资料库;在线期刊;美国生理学杂志;2004年第287卷第7期FunctionalFoodsNutraceuticalsinCancerPrevention,
...aguestheorganizationandcontentofthisambitiousbook.Thefirstsectionofthebook,titled“ApproachestoCancerPrevention:RoleofNutrition,“launchesintoan18-pagechaptertitled“AntioxidantsasCancerTherapies“thatbeginswithareviewofthebasicchemicalreactionsunderlyingtheformationofreactiveoxygenspeciesandend...
医源资料库;在线期刊;美国临床营养学杂志;2004年79卷第2期PI3K-AktPathwaySuppressesCoagulationandInflammationinEndotoxemicMice
...issuefactor(TF).Inthisstudy,weanalyzedtheroleofthephosphoinositide3-kinase(PI3K)-Aktpathwayintheactivationofcoagulationandtheinnateimmuneresponseinamousemodelofendotoxemia.MethodsandResults—WortmanninandLY294002wereusedtoinhibitthePI3K-Aktpathway.WefoundthatwortmannininhibitedLPS-inducedAktphospho...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第10期氨基酸分子的模糊聚类分析
【摘要】本文选用氨基酸分子的相对分子量、pI值、疏水性值以及保守性值这四个参数,利用模糊聚类的方法,对20种氨基酸分子进行了分类。通过对分类结果的分析,有助于我们研究蛋白质的相似性问题。【关键词】氨基酸;...
医源资料库;在线期刊;中华医学研究杂志;2006年第6卷第2期资深PI最新文章解析信号通路
来自新加坡分子与细胞生物学研究院,癌症与发育细胞生物学部的研究人员获得了YAP-TEAD4复合物在YAP因子N端结构域相互作用,以及在TEAD4C端结构域与YAP相互作用的晶体结构,从中研究人员认为YAP中的PXXΦP片段是与TEAD4相互作用...
行业资讯;临床快报;细胞分子与蛋白质组Adenovirus-MediatedIntraarterialDeliveryofPTENInhibitsNeointimalHyperplasia
...Durham,NC27710.E-mailcdkontos@duke.eduAbstractObjective—Phosphoinositide(PI)3-kinasepromotesvascularsmoothmusclecell(VSMC)responsesnecessaryforneointimalhyperplasia.Werecentlydemonstratedthattheinositol3-phosphatasePTENisexpressedinVSMCsandthatitsoverexpressioninhibitsthesecellularresponses.Thepur...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第2期Inhibitionofphosphatidylinositol3-kinasestimulatesactivityofthesmall-conductanceKchannelintheCCD
...WeusedWesternblottingtoexaminetheexpressionofphosphatidylinositol3-kinase(PI3K)intherenalcortexandoutermedullaandemployedthepatch-clamptechniquetostudytheeffectofPI3KontheROMK-likesmall-conductanceK(SK)channelsinthecorticalcollectingduct(CCD).LowKintakeincreasedtheexpressionofthe110-kDa-subunit(p110...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第4期PI3Kintegratestheactionofinsulinandleptinonhypothalamicneurons
...shington,USA.AbstractCentralcontrolofenergybalancedependsontheabilityofproopiomelanocortin(POMC)oragouti-relatedprotein(Agrp)hypothalamicneuronstosenseandrespondtochangesinperipheralenergystores.Leptinandinsulinhavebeenimplicatedascirculatingindicatorsofadiposity,butitisnotclearhowchangesintheirleve...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第4期纳洛酮对重型颅脑损伤脑血流动力学及颅内压的影响
...压监护仪监测颅内压。结果治疗组脑血流动力学Vs、Vm、PI值在纳洛酮治疗3天后与对照组相比明显改善(P<0.05);治疗组在第3天后平均颅内压明显低于对照组(P<0.05)。结论大剂量纳洛酮能够改善重症颅脑损伤引起的脑血流动...
医源资料库;在线期刊;中华现代临床医学杂志;2006年第4卷第4期