IdentificationofImmunodominantEpitopesontheMembraneProteinoftheSevereAcuteRespiratorySyndrome-AssociatedCoronavirus
ViralImmunologyLaboratory,LindsleyF.KimballResearchInstitute,NewYorkBloodCenter,NewYork,NewYork10021DepartmentofMolecularBiology,BeijingInstituteofMicrobiologyandEpidemiology,Beijing100071,PeoplesRepublicofChinaABSTRACTSimilartoothercoronaviruses,themembrane(M)proteinofsevereacuterespiratorysyndrome...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第8期ActivityoftherenalNa+-K+-2Cl-cotransporterisreducedbymutagenesisofN-glycosylationsites:roleforproteinsurfacechargeinCl-transport
【摘要】Therenal-specificNa+-K+-2Cl-cotransporterNKCC2belongstotheSLC12genefamily;itisthetargetforloopdiureticsandthecauseoftypeIBartter‘ssyndrome.BecausetheNKCC2sequencecontainstwoputativeN-linkedglycosylationsites,oneofwhichisconservedwiththerenalNa+-Cl-cotransporterinwhichglycosylationaffec...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第5期-GalactosidaseADeficiencyLeadstoIncreasedTissueFibrinDepositionandThrombosisinMiceHomozygousfortheFactorVLeidenMutation
...ardiovascularMedicine,(Y.S.,P.F.B.,F.B.V.,K.A.O.,D.T.E.),DivisionofNephrology(J.A.S.),andDepartmentofPathology(J.W.H.,D.G.),UniversityofMichiganMedicalCenter,AnnArbor.AbstractBackground—FactorVLeiden(FVL)isacommongeneticriskfactorforvascularthrombosisinhumans.Fabrydisease,anX-linkedlysosomalstorag...
医源资料库;在线期刊;中风学杂志;2006年第37卷第4期四、处方常用拉丁词缩写与中文对照表
...culum早饭前a.m.Antemeridiem上午,午前a.p.Anteparndium午饭前a.u.agitAnteusumagitetur使用前振荡Abs.febr.Absentefebri不发烧时Ac.;acid.Acidum酸Ad.;addAd到、为、加至AdlidAdlibitum随意、任意量AdusAdusum应用Adus.extAdusumexternum外用Adus.int.Adusuminternum内服Alt.die....
医源资料库;医源图书馆;教材类;医院药学基层医院无心肌酶检测条件下对不典型心肌梗死的诊治
...痛,舌下含化速效救心丸,静滴强化极化液+硝酸甘油等综合治疗。2天后疼痛渐缓停止。入院后48h体温开始升高。波动于37.5℃~38.5℃之间,持续6天自然消退。入院48h化验,WBC13.6×109/L,N0.80,L0.20;ESR60mm/h;肝功:谷丙转氨酶(ALT)6...
合作平台;在线期刊;中华中西医杂志;2004年第5卷第24期;经验交流Thegeneticepidemiologyofneurodegenerativedisease
GeneticsandAgingResearchUnit,MassGeneralInstituteforNeurodegenerativeDiseases,DepartmentofNeurology,MassachusettsGeneralHospital,HarvardMedicalSchool,Charlestown,Massachusetts,USA.AbstractGenedefectsplayamajorroleinthepathogenesisofdegenerativedisordersofthenervoussystem.Infact,ithasbeentheveryknowl...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第6期DifferentialEffectsofGq,G14,andG15onVascularSmoothMuscleCellSurvivalandGeneExpressionProfiles
DepartmentofPharmacology(R.D.P.,K.B.H.,A.L.,R.B.F.,K.X.,C.J.L.,T.J.M.,J.R.H.)andBiomolecularComputingResource(T.T.L.,K.G.),EmoryUniversitySchoolofMedicine,Atlanta,GeorgiaAbstractGqfamilymembers(Gq,G11,G14,andG15/16)stimulatephospholipaseC(PLC)andinositollipidsignalingbutdiffermarkedlyinaminoacidsequ...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第6期ComplementreceptorsregulatedifferentiationofbonemarrowplasmacellprecursorsexpressingtranscriptionfactorsBlimp-1andXBP-1
1CytosBiotechnology,SwissFederalInstituteofTechnology,Zurich-Schlieren8952,Switzerland2MolecularBiomedicine,SwissFederalInstituteofTechnology,Zurich-Schlieren8952,SwitzerlandHumoralimmuneresponsesarethoughttobeenhancedbycomplement-mediatedrecruitmentoftheCD21–CD19–CD81coreceptorcomplexintotheBce...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第6期Subtype-SpecificAffinityforCorticosteroneofRatOrganicCationTransportersrOCT1andrOCT2DependsonThreeAminoAcidswithintheSubstrateBindingRegi
InstituteofAnatomyandCellBiology,UniversityofWezburg,Wezburg,GermanyAbstractTheaffinityofcorticosteronetoorganiccationtransporters(OCTs)issubtype-andspecies-dependent.Forexample,theIC50valuesforcorticosteroneinhibitionofcationuptakebytransportersrOCT1andrOCT2are150and4e,respectively.Byintroducingdom...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第5期人参皂苷Rg2对脑缺血再灌注大鼠学习记忆及海马神经元Glu和NMDA受体亚单位表达的影响
...的观察全脑缺血再灌注对大鼠空间学习记忆和海马神经元Glu、N-甲基-D-天冬氨酸受体(NMDAR)亚单位NR1、NR2B表达的影响,探讨人参皂苷Rg2的干预作用。方法SD大鼠56只,采用四血管阻断法制备大鼠全脑缺血再灌注模型(假手术组除...
医源资料库;在线期刊;齐鲁医学杂志;2006年第21卷第4期