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KininostatinAssociatesWithMembraneRaftsandInhibitsvβ3IntegrinActivationinHumanUmbilicalVeinEndothelialCells
...iferation,migration,andangiogenesis.Angiogenesisistheprocessofformationofnewbloodvesselsfromtheexistingmicrovessels,initiatedbystimulationofvascularECswithgrowthfactorsandcytokines.Thefunctionalsignificanceofcaveolaeinangiogenesishasbeensuggestedbydefectivenitricoxide–dependentangiogenesisinca...
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第9期 -
AutocrineVEGF-AsysteminpodocytesregulatespodocinanditsinteractionwithCD2AP
...F-Aregulatestheexpressionofslit-diaphragmproteinsinpodocytes.A:Westernblot(WB)showingadose-responsecurveindicatingthatVEGFupregulatespodocinexpression;WBreprobedforactinisshowntodocumentequalloading.B:quantitationofVEGF165-inducedpodocinupregulation(means±SE,n=4,*P<0.05).C:WBshowingthatVEGF-A...
医源资料库；在线期刊；美国生理学杂志；2006年第289卷第8期 -
Fluidandelectrolytesupplementationforexerciseheatstress
...csandsafetyII.London:TaylorFrancis,1990:897–904.NelsonN,EichnaLW,Bean,WB.Determinationofwaterandsaltrequirementsfordesertoperations.FortKnox,KY:ArmoredForceMedicalResearchLaboratory,1943.(Reportno.2-6.)GreenleafJE.Environmentalissuesthatinfluenceintakeofreplacementbeverages.In:MarriottBM,ed.Flu...
医源资料库；在线期刊；美国临床营养学杂志；2000年72卷第2期 -
HS1proteinisdifferentiallyexpressedinchroniclymphocyticleukemiapatientsubsetswithgoodorpoorprognoses
...hown.Theantibodyhybridizesinanareacorrespondingtotheproteinspotsofinterest.WB,Westernblot.MSanalysisidentifiesHS1astheproteindifferentiallyexpressedinthe2subsetsofCLLpatients.The2proteinspotswereexcisedfrom2-DEgelsandanalyzedbymatrix-assistedlaserdesorption/ionization–time-of-flight(MALDI-TOF)MS,a...
医源资料库；在线期刊；临床研究杂志；2005年第115卷第6期 -
TypeIInterferonProductionIsProfoundlyandTransientlyImpairedinPrimaryHIV-1Infection
...(Paris,France).Primaryinfectionwasdiagnosedby(1)anindeterminateWesternblot(WB)result,(2)apositivep24antigenemiaordetectableplasmaHIVRNAwithanegativeorweaklypositiveELISAresult,or(3)apositiveELISAresultafteranegativeresult3monthsearlier.Infectiondatewasestimatedas(1)thedateofsymptomonsetminus15days,(...
医源资料库；在线期刊；传染病学杂志；2005年第191卷第14期 -
Conjugatedlinoleicacidsupplementationfor1yreducesbodyfatmassinhealthyoverweighthumans
...er.Repeatedmeasurements(n20)performedwiththeuseofaHologicwhole-bodyphantom(WB-1406;HologicInc,Waltham,MA)ateachmedicalcentershowednosignificantdifferencebetweenthecenters.Thesubjectswereweighedondigitalscales(TBF-305;Tanita,Yiewsley,UnitedKingdom)intheirunderwear.Nosubtractionsforclotheswereperforme...
医源资料库；在线期刊；美国临床营养学杂志；2004年79卷第6期 -
AcquiredpredispositiontomycobacterialdiseaseduetoautoantibodiestoIFN-
...tionofIFN-.Figure1IFN-productioninresponsetomitogenstimulationinwholeblood(WB)andisolatedPBMCs.IFN-wasnotdetectedinpatients’plasmaderivedfromwholebloodafterstimulationwithPHA(orPMA/ionomycininpatient2),whereaslargequantitiesofIFN-weredetectedwhenisolatedPBMCswerestudiedintheabsenceofpatientplasma....
医源资料库；在线期刊；临床研究杂志；2005年第115卷第9期 -
Inorganicmercuryinteractswithcysteineresidues(C451andC474)ofhOCT2toreduceitstransportactivity
...cmercuryintheenvironmentthattendstoaccumulateinthekidneys(seeextensivereviewbyRef.27).Wefoundthat,whereasC437andC470remainedrefractorytothesesmallerreagents,bothC451andC474wereexposedtotheaqueousmilieuofthehydrophiliccleftofhOCT2.METHODSChemicals.[3H]tetraethylammonium(54Ci/mmol)wassynthesizedbyAmer...
医源资料库；在线期刊；美国生理学杂志；2007年第290卷第5期 -
IdentificationofEpstein-Barrvirusproteinsasputativetargetsoftheimmuneresponseinmultiplesclerosis
...-kDafull-lengthbandonSDS-PAGE(SDS)afterCoomassiestaining(left).Westernblot(WB)andimmunostainingwithCSFofacontroldonor(Ctr;middle)andofarepresentativeMSpatient(right)confirmedthespecificbindingofCSFIgGtotheBRRF2proteins.(D)ImmunoreactivitytorecombinantBRRF2(upperpanels)andEBNA-1(lowerpanels)wasinvest...
医源资料库；在线期刊；临床研究杂志；2005年第115卷第5期 -
MolecularDeterminantsofSubstrate/InhibitorBindingtotheHumanandRabbitRenalOrganicCationTransportershOCT2andrbOCT2
...cubatingeachwellofcellsintwosuccessive15-minexposuresto1mlofWaymouthbuffer(WB)(135mMNaCl,13mMHEPES,2.5mMCaCl2·2H2O,1.2mMMgCl2,0.8mMMgSO4·7H2O,5mMKCl,and28mMglucose).Afterthepreincubations,400e蘬of“transportbuffer“containing(typically)0.4e藽i/ml[14C]TEA(10e),and,insomecases,increasingconcentr...
医源资料库；在线期刊；分子药理学杂志；2005年第67卷第4期