Linkagedisequilibriummapsandassociationmapping
...ine,epidemic,migration,orotherfactors.LetthefounderhaplotypefrequenciesbeamixtureofextremeLDwithprobability0andacomplementaryfrequencywithLD=0:ProbabilityThefrequencyoftherarestalleleisQ,andRisthefrequencyoftheassociatedallele.Then0isdefinedastheassociationprobabilityinfounders,andtheexpecteddecayof...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第6期Energyadaptationsinhumanpregnancy:limitsandlong-termconsequences
...nderprivilegedpopulations.REFERENCESRoweAW,BoydWC.Themetabolisminpregnancy.IX.Thefoetalinfluenceonthebasalrate.JNutr1932;5:55169.HyttenF,LeitchI.Thephysiologyofhumanpregnancy.2nded.Oxford,UnitedKingdom:BlackwellScientificPublications,1971.HyttenF.Nutrition.In:HyttenF,ChamberlainG,eds.Clinicalp...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第5期Applicationoffemtosecondultrashortpulselasertophotodynamictherapymediatedbyindocyaninegreen
...a1cmcell.Themeanpowerdensitywasmeasuredtodegeneratethegelatin.Usinggelatinmixedwith1.5mg/dlofICG,themeanpowerdensityalsowasmeasured.CornealneovascularisationThisstudywasconductedinaccordancewiththeAssociationforResearchinVisionandOphthalmologyStatementfortheUseofAnimalsinResearch.Toevaluatetheeffect...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第6期Largermassofhigh-metabolic-rateorgansdoesnotexplainhigherrestingenergyexpenditureinchildren
...l.Body-compositionmeasuresBodyweightwasmeasuredtothenearest0.1kg(WeightTronix,NewYork)andheighttothenearest0.5cmbyusingastadiometer(Holtain,Crosswell,UnitedKingdom).Totaladiposetissueandskeletalmusclemassweremeasuredbyusingwhole-bodymultisliceMRI.Subjectswerepositionedonthe1.5-Tscanner(6XHorizon;Gen...
医源资料库;在线期刊;美国临床营养学杂志;2003年77卷第6期UltrasoundStimulatesCyclooxygenase-2ExpressionandIncreasesBoneFormationthroughIntegrin,FocalAdhesionKinase,Phosphatidylinositol3-Kinase,andAkt
...orsthatregulatecellviabilityinresponsetocuesderivedfromtheextracellularmatrix(Ruoslahti,1996;GiancottiandRuoslahti,1999).Inthecaseofmesenchymalcells,encompassedbytheextracellularmatrix,matrix-derivedmechanicalstimulicanregulatetheirviability.Inthislatterscenario,integrinsfunctionasmechanoreceptorsth...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第6期C-ReactiveProteinIsAssociatedWithArterialStiffnessinApparentlyHealthyIndividuals
...ndthesystemshowsgoodrepeatabilityofmeasurements.20Aorticaugmentationindex(AIx)andheartrateweredeterminedusingtheintegralsoftware.Augmentationindex,ameasureofsystemicarterialstiffness,21wascalculatedasthedifferencebetweenthesecondandfirstsystolicpeaks,expressedasapercentageofthepulsepressure.Theaorti...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第5期Anovelargininesubstitutionmutationin1Adomainandanovel27bpinsertionmutationin2Bdomainofkeratin12geneassociatedwithMeesmann’scornealdy
...sensemutationreplacingahighlyconservedarginineresidueinthebeginningofthehelixinitiationmotifwasfoundinonepatient,andaninsertionmutation,consistingofaduplicationof27nucleotides,wasfoundbeforethehelixterminationmotifintheother.Keywords:Meesmann’scornealdystrophy;genetics;keratinMeesmann’scornealdy...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第6期改良Ilizarov技术结合有限手术矫正马蹄内翻足畸形
...tis,13bycongenitaltalipesequino-varus.Inaccordancewithdeformities,externalfixatorandlimitiedoperativemethodsweredertermined.Thelimitedreleaseofsofttissuewereperformedin7patients,limitedosteotomyin25patients.Thedynamicmusclebalanceoperationwereperformedin9patientswithimbalanceofmusclestrength.Accordi...
医源资料库;在线期刊;中国矫形外科杂志;2008年第16卷第5期Influenceofastearicacidrichstructuredtriacylglycerolonpostprandiallipemia,factorVIIconcentrations,andfibrinolyticactivityinhealthysubj
...fthevenipuncturesample,a4.5-mLsamplewascollectedinto0.5mLofananticoagulantmixtureofTrasylol,EDTA,andathrombininhibitor(Byk-Sangtec,Dietzenbach,Germany)inachilledtubeandcentrifugedat1500xgfor15minat4°CfordeterminationofplasmafibrinopeptideA(FPA),whichisamarkerofthrombinactivityonfibrinogen.Blood...
医源资料库;在线期刊;美国临床营养学杂志;2001年73卷第4期FactorIXaInhibitorsasNovelAnticoagulants
...plications,increasedbleedingrisk,anddrug-inducedthrombophilia.BecausefactorIXplaysapivotalroleintissuefactor(TF)-mediatedthrombingeneration,itmayrepresentapromisingtargetfordrugdevelopment.SeveralmethodsofattenuatingfactorIXactivity,includingmonoclonalantibodies,syntheticactivesite-blockedcompetitiv...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期