FDA授予AlnylamRNAi药物ALN-AT3孤儿药地位
全球领先的RNAi药物开发公司——Alnylam制药8月20日宣布,FDA已授予ALN-AT3孤儿药地位(OrphanDrugDesignation,ODD),用于治疗A型血友病患者。上周,FDA也已授予ALN-AT3治疗B型血友病的孤儿药地位。目前,Alnylam正开发ALN-AT3作为一种皮下...
医药经济;生物技术;技术要闻Nutrients,foods,anddietarypatternsasexposuresinresearch:aframeworkforfoodsynergy
...olis,MN55454.E-mail:jacobs{at}epi.umn.edu.ABSTRACTEvidenceissynthesizedthatfoodsandfoodpatternsactsynergisticallytoinfluencetheriskofseveralchronicdiseases.Whole-grainconsumptionandriskofdiseasearepresentedasamodeloffoodsynergy.Foodsynergyisdefinedasadditiveormorethanadditiveinfluencesoffoodsandfood...
医源资料库;在线期刊;美国临床营养学杂志;2003年78卷第3期Alifecyclemicronutrientperspectiveforwomen‘shealth
...improvethequalityofadietandtoobtainadequateamountsofvitaminsandmineralsfromfoods,food-basedapproachesarestillnotattainingadequateintakesinmostwomen,bothintheUnitedStatesandworldwide.Effortsareneededtoimprovedietquality,focusingonthedietasawhole,andnotonsinglevitaminsorminerals.However,considerationm...
医源资料库;在线期刊;美国临床营养学杂志;2005年81卷第5期ComparisonbetweenplasmaanderythrocytefattyacidcontentasbiomarkersoffattyacidintakeinUSwomen
...idchromatographyin306USwomenaged4369y.Fattyacidintakewasassessedwithafood-frequencyquestionnaire,whichwasvalidatedformeasuringintakesofvariousfattyacids.Results:Docosahexaenoicacid(DHA,22:6n3)inerythrocytesandplasmaprovidedthestrongestcorrelationswithitsintake,buterythrocyteDHAconcentrat...
医源资料库;在线期刊;美国临床营养学杂志;2007年86卷第1期Alcoholicbeveragepreference,diet,andhealthhabitsintheUNCAlumniHeartStudy
...inkinghabitswereusedaspredictorsofhealthbehaviorsandofintakesofnutrientsandfoodgroups.Results:Subjectswhopreferredwinehadhealthierdietsthandidthosewhopreferredbeerorspiritsorhadnopreference.Winedrinkersreportedeatingmoreservingsoffruitandvegetablesandfewerservingsofredorfriedmeats.Thedietsofwinedrin...
医源资料库;在线期刊;美国临床营养学杂志;2002年76卷第2期Treatmentofanemiawithmicroencapsulatedferrousfumarateplusascorbicacidsuppliedassprinklestocomplementary(weaning)foods
...mgelementalFe)inpowderformplusascorbicacidtobesprinkledontoanycomplementaryfoodeaten(sprinklesgroup);acontrolgroupreceivedferroussulfatedrops3times/dfor2mo(totaldose:40mgelementalFe).Hemoglobinandserumferritinconcentrationsweremeasuredatbaselineandattheendoftreatment.Results:Successfultreatmentofane...
医源资料库;在线期刊;美国临床营养学杂志;2001年74卷第6期Reproducibilityandvalidityofdietaryglycemicindex,dietaryglycemicload,andtotalcarbohydrateintakein141Swedishmen
...onregardingthereproducibilityandvalidityofthesemeasuresassessedwiththeuseoffood-frequencyquestionnaires(FFQs)islacking.Objective:WeexaminedthereproducibilityandvalidityofdietaryGIanddietaryGLandofcarbohydrateintakeasassessedbyusinganFFQ.Design:Swedishmen(n=141)aged4074ycompleted2FFQs1yapartand...
医源资料库;在线期刊;美国临床营养学杂志;2007年85卷第2期深圳市熟食中食源性致病菌污染状况的调查研究
...、单增李斯特菌增菌液及选择性琼脂培养基购于北京陆桥技术有限公司,均在有效期内使用。14分析仪VITEK—AMS全自动微生物分析仪2结果21熟食中食源性致病菌检出情况340份熟食共检出致病菌20株,总检出率为59%,其中其中...
医源资料库;在线期刊;中国热带医学杂志;2005年第5卷第2期BotanicalMedicine:Efficacy,QualityAssurance,andRegulation
...iceofAlternativeMedicineoftheNationalInstitutesofHealthincooperationwiththeFoodandDrugAdministration.Thechaptersaregroupedintheusual(butuseful)categories:1)identityanduse,2)evidenceofefficacy,3)evidenceandassessmentofsafety,4)qualityassuranceanditsregulation,and5)effectsofregulationsonthemarketplace...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第2期Developingandimplementingfood-baseddietaryguidanceforfatinthedietsofchildren
...fscientificguidelinessuitableforitspopulation,butalsostrategiesforeffectivefood-baseddietaryguidancetoachievethegoal.Thisisbestdonebyintegratinghealthanddietarygoalswhenformingscientificguidelinesandbydevelopingeffectivepartnershipsamongthemanysectorsthatinfluencethefoodsupplyandfoodselection.Usingf...
医源资料库;在线期刊;美国临床营养学杂志;2000年72卷第5期