Sequentialdevelopmentofinterleukin2–dependenteffectorandregulatoryTcellsinresponsetoendogenoussystemicantigen
...Transferofnaiveantigen-specificCD4+Tcellsintolymphopenicmicethatexpressanendogenousantigenasasystemic,secretedproteinresultsinsevereautoimmunityresemblinggraft-versus-hostdisease.Tcellsthatrespondtothisendogenousantigendevelopintoeffectorcellsthatcausethedisease.Recoveryfromthisdiseaseisassociatedwi...
医源资料库;在线期刊;实验医学杂志;2005年第202卷第10期CD4+Tcellsthatenterthedraininglymphnodesafterantigeninjectionparticipateintheprimaryresponseandbecomecentral–memorycells
...bbreviationused:HA,hemagglutinin.A.A.Itano‘spresentaddressisAmgen,ThousandOaks,CA91320.NaiveTlymphocytesareactivatedthroughtheirTCRsbypeptide–MHCcomplexesdisplayedondendriticcellsinsecondarylymphoidtissue(1).Uponactivation,Tcellsundergorapidproliferation,differentiatingintoeffectorscapableofmigr...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第4期病案统计工作在ISO9000质量管理体系运行中的职能
...基础,ISO质量管理体系强调的是过程控制即:Plan(计划)-Do(实施)-Check(检查)-Action(纠正),在PDCA的循环中病案统计工作发挥着重要的职能,起着较大的作用。 1Plan(计划)阶段 医院在推行ISO质量管理体系前期阶段必须...
医源资料库;在线期刊;中华现代医院管理杂志;2006年第4卷第3期Teaching,learning,doing:bestpracticesineducation
...tHarvardMedicalSchoolisdevelopingbestpracticesinteachingthatwillequipfuturedoctorstoreducehealthilliteracyandpromotepositivechangesinthinkingandbehaviorintheirpatients.Modelsofhowpeoplelearncanhelpphysiciansselecttasks,questions,andpromptsthatadvanceteachingandlearning.Tokeepandusenewinformation,adu...
医源资料库;在线期刊;美国临床营养学杂志;2005年82卷第1期AcutedecreaseinrenalmicrovascularPO2duringacutenormovolemichemodilution
...摘要】LargedifferencesinthetoleranceoforgansystemstoconditionsofdecreasedO2deliverysuchashemodilutionexist.Thekidneyreceives25%ofthecardiacoutputandO2deliveryisinexcessoftheoxygendemandundernormalcircumstances.Inaratmodelofacutenormovolemichemodilution(ANH),westudiedtheeffectofreducedhematocriton...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第2期RecoveryFromAphasiaAfterHemicraniectomyforInfarctionoftheSpeech-DominantHemisphere
...scontroversyregardingtheuseofthismethodinpatientswithinfarctionofthespeech-dominanthemisphere.Methods—In14patientswithinfarctionofthedominanthemisphereandsubsequenttreatmentwithhemicraniectomy,recoveryfromaphasicsymptomswasevaluatedretrospectively.Agroupofpatientswhoweretreatedbetween1994and2003in...
医源资料库;在线期刊;中风学杂志;2005年第36卷第4期RegulationofperipheralTcellactivationbycalreticulin
...sintegrity.Calreticulin(CRT)isamajorCa2+bufferingchaperoneinthelumenoftheendoplasmicreticulum.HereweinvestigatedtheimpactofCRTdeficiencyonTcellfunctioninimmunodeficientmicereconstitutedwithfetallivercrt–/–hemopoieticprogenitors.Thesechimericmicedisplayedsevereimmunopathologicaltraits,whichcorrel...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第2期肺动脉导管在危重症中的临床应用
...气囊应充满气体(1.5ml)以包围导管尖端;同时严密监测心电图,并提前准备好抢救药品及除颤仪,出现室颤立即电击除颤。5例患者置管困难,但经改变体位及方向后最终置管成功。未发生心内打结、心血管损伤破裂等严重并发...
医源资料库;在线期刊;中华现代临床医学杂志;2006年第4卷第1期口腔试题
...入睡,含凉水后疼痛可有缓解。全身情况:健康检查:26DO大面积银汞充填体,远中已折裂。银汞充填体边缘不密合。冷测疼痛,叩诊(+)。远中邻面食物嵌塞,牙龈红肿明显。36DO大面积银汞充填体,充填体边缘不密合。叩诊...
医源资料库;医源习题集;口腔医学大鼠下颌骨牵引成骨过程中骨改建机制的探讨
...rkappaBligand,RANKL)在下颌骨牵引成骨(distractionosteogenesis,DO)过程中的表达,揭示DO过程中骨改建的规律。研究者选用42只成年雄性SD大鼠下颌骨牵引成骨模型,牵引程式:间歇期5d,牵引速度0.2mm×2次/d,牵引期6d,稳定期4周。...
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