Estrogen,HeatShockProteins,andNFBinHumanVascularEndothelium
...Houston,Tex.ABSTRACTBackground—WehypothesizedthatestrogenwouldincreaseHSP72inhumancoronaryarteryendothelialcells(HCAEC),andthatthesewouldbemoresensitivetoestrogenthanourpreviousobservationsinmyocytes.MethodsandResults—HCAECweretreatedwith17?-estradiolortamoxifen,rangingfromphysiologicaltopharmac...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第9期肾小管上皮细胞ATP耗竭再恢复时热休克蛋白72与Paxillin的相互作用
...为了研究肾小管上皮细胞ATP耗竭再恢复时热休克蛋白(HSP)72与桩蛋白(Paxillin)的相互作用和意义。研究者应用代谢抑制剂暂时性阻断肾小管上皮细胞ATP的生成,引起细胞内的ATP耗竭;换用含10mmol/L葡萄糖的DMEM培养液,使细胞内ATP再...
行业资讯;临床快报;肾脏相关Noassociationofp53codon72andp21codon31polymorphismsinTaiwanChinesepatientswithpterygium
...sineitherp53orp21aredetectedinmanytumourcells,3,4andpolymorphismsofp53codon72orp21codon31werefoundtobeassociatedwithmanytumours.5,6Becauseoftheabnormalexpressionofthep53geneinpterygiumepithelium1,2andthereisevidencethathereditaryfactorsmayhavearoleinthedevelopmentofpterygium,7,8itislogicaltosuspectt...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第7期EvidenceforHSP-mediatedcytoskeletalstabilizationinmesothelialcellsduringacuteexperimentalperitonealdialysis
...rassay,basedoncoincubationofcytoskeletalproteinfractionswithrecombinantHSP-72orHSP-72antibodies.Intheratmodel,detachmentofmesothelialcellsfromtheirperitonealmonolayerduringinvivoPDFexposurewasassessedwithandwithoutoverexpressionofHSP-72(byheatconditioning).Invitro,cytoskeletaldisruptiononsublethalPD...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第1期HeatShockProteinsandMitogen-activatedProteinKinasesinSteatoticLiversUndergoingIschemia-Reperfusion:SomeAnswers
...elevelsweremeasuredafterreperfusion.WereportthatpreconditioningincreasedHSP72andheme-oxygenase-1(HO-1)at6and24hoursofreperfusion,respectively.Unlikenonsteatoticlivers,steatoticliversbenefitedfromHSP72activators(geranylgeranylacetone)throughoutreperfusion.ThisprotectionseemedattributabletoHO-1inducti...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第5期HSP72预先诱导对大鼠肝脏长时间低温保存的保护作用
【摘要】目的观察阿霉素(Doxorubicin,DXR)诱导HSP72对大鼠肝脏长时间冷保存的保护作用。方法实验组SD大鼠按1mg/kgDXR给药,对照组给予生理盐水,48h后用4℃林格液和UW液行肝脏原位冷灌注,肝脏UW液4℃保存24、36、48h,检测保存...
资料库;在线期刊;中华现代外科学杂志;2004年第1卷第2期Vasospasmandp53-InducedApoptosisinanExperimentalModelofSubarachnoidHemorrhage
...hisstudy,weinvestigatedtheroleofp53-inducedapoptosisinthevasculatureat24and72hours.Tocompletelyexaminetheapoptoticcascades,keyproteinsofthecaspase-dependent,-independentandmitochondrialpathwayswereexamined.Methods—Inthisstudy,adultratsweredividedinto3groups:sham(n=21),nontreatment(subarachnoidhemo...
医源资料库;在线期刊;中风学杂志;2006年第37卷第7期Variationsinthepreproghrelingenecorrelatewithhigherbodymassindex,fatmass,andbodydissatisfactioninyoungJapanesewomen
...ucleotidepolymorphisms(SNPs)whoseminorallelefrequencieswere0.05theLeu72Met(408CA)SNPinexon2andthe3056TCSNPinintron2wereusedforassociationanalysis.The3056Callelewassignificantlyassociatedwithahigheracylatedghrelinconcentration(P=0.0021),bodyweight(P=0.011),bodymassindex(P=0.007),fatmass(P...
医源资料库;在线期刊;美国临床营养学杂志;2007年86卷第1期第72章 颈椎损伤
第72章 颈椎损伤 颈椎损伤是一种严重损伤,合并脊髓损伤、四肢瘫者约占半数,病死率约15%。 一、颈椎损伤分型 (一)屈曲型损伤较为常见。多为低头工作时,高速坠落的重物打击于头部,或患者高位跌落时头...
医源资料库;医源图书馆;教材类;急诊医学联合检测B72.3、癌胚抗原、神经特异性钙结合蛋白、血栓素在浆膜腔积液细胞学鉴别诊断中的价值
目的探讨B72.3、癌胚抗原、神经特异性钙结合蛋白、血栓素组合检测在浆膜腔积液中恶性间皮瘤和增生间皮细胞与腺癌鉴别诊断的价值.方法取123例浆膜腔积液,经活检或临床资料证实为转移腺癌89例、恶性间皮瘤8例、增生间皮细...
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