YM-244769,aNovelNa+/Ca2+ExchangeInhibitorThatPreferentiallyInhibitsNCX3,EfficientlyProtectsagainstHypoxia/Reoxygenation-InducedSH-SY5YNeuronal
...KB-R7943),protectedagainsthypoxia/reoxygenation-inducedcelldamageinneuronalSH-SY5Ycells,whichexpressNCX1andNCX3,moreefficientlythanthatinrenalLLC-PK1cells,whichexclusivelyexpressNCX1,whereas2-[4-(4-nitrobenzyloxy)benzyl]thiazolidine-4-carboxylicacidethylester(SN-6)suppressedrenalcelldamagetoagreater...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第12期对聋生如何正确掌握语音知识训练
...气流从窄缝中挤出来,不颤动声带,ch送气,zh不送气。sh发音时舌尖稍翘起,跟硬腭接近,气流从中挤出,摩擦成音,声带不颤动,r是舌尖后阻浊擦音,与sh的成阻部位相同,不同点在于r要颤动声带。 2韵母 韵母分为单...
医源资料库;在线期刊;中国民康医学;2006年第18卷第7期丹参单体对TNF-α诱导大鼠动脉平滑肌细胞MCP-1和IL-1β的影响
丹参单体对TNF-α诱导大鼠动脉平滑肌细胞MCP-1和IL-1β的影响(pdf)【摘要】目的观察丹酚酸B和丹参酮ⅡA对肿瘤坏死因子(TNF-α)诱导的血管平滑肌细胞(SMC)白细胞介素-1β(IL-1β)和单核细胞趋化蛋白-1(MCP-1)的影响,探讨丹参...
医源资料库;在线期刊;中华现代中医学杂志;2006年第2卷第7期MastCell-DerivedTumorNecrosisFactorCanPromoteNerveFiberElongationintheSkinduringContactHypersensitivityinMice
...-deficientmiceorinTNFC/Cmastcell-engraftedc-kitmutantmice.Theseobservationsshowthatmastcells,andmastcell-derivedTNF,canpromotetheelongationofcutaneousnervefibersduringcontacthypersensitivityinthemouse.--------------------------------------------------------------------------------Severallinesofevide...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第11期Mastcellscanpromotethedevelopmentofmultiplefeaturesofchronicasthmainmice
...acandMuc5b,andincreasedlevelsoflungcollagen.Usingmastcell–deficient(KitW-sh/W-shand/orKitW/W-v)miceengraftedwithFcR+/+orFcR–/–mastcells,wefoundthatmastcellswererequiredforthefulldevelopmentofeachofthesefeaturesofthemodel.However,somefeaturesalsowereexpressed,althoughusuallyatlessthanwild-typel...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第6期载脂蛋白E在神经细胞中表达对细胞功能的影响
...,探讨apoE4在AD发病中的相关机制。研究方法筛选转染SK-N-SH定位观察表达鉴定功能分析构建真核表达质粒重组pEGFP-apoE质粒酶切电泳图apoE3Query:321cgcaggcccggctgggcgcggacatggaggacgtgtgcggccgcctggtgcagtaccgcg380|||||||||||||||||||||||||||||||||||||||||||||||||...
医源资料库;医学文档库;心血管相关InteractionofCagAwithCrkplaysanimportantroleinHelicobacterpylori–inducedlossofgastricepithelialcelladhesion
...rEvolutionalScienceandTechnology,JapanScienceandTechnologyAgency,Kawaguchi-shi,Saitama332-0012,JapanCagAproteinisamajorvirulencefactorofHelicobacterpylori,whichisdeliveredintogastricepithelialcellsandelicitsgrowthfactor–likeresponses.Oncewithinthecells,CagAistyrosinephosphorylatedbySrcfamilykinase...
医源资料库;在线期刊;实验医学杂志;2005年第202卷第9期高效液相色谱法测定冠心丹参滴丸中丹酚酸B的含量
【摘要】目的测定冠心丹参滴丸中丹酚酸B的含量。方法HPLC法,ODS2-C18色谱柱(250mm×4.6mm,5μm),流动相:(甲醇-乙腈)∶(甲酸-水)=37∶63,其中甲醇∶乙腈=3∶1,甲酸∶水=1∶29;流速1.0ml·min-1;检测波长为286nm。结果丹酚酸B浓度在...
药品天地;专业药学;实验技术;色谱技术;色谱论文X-连锁无丙种球蛋白血症的研究进展
...有120个氨基酸,TH(Techomology;TH)段约有60~80个氨基酸SH3(Srchomology3;SH3)段约有60个氨基酸,SH2段约100个氨基酸,激酶催化段约280个氨基酸[6]。图1BTK蛋白的组成(从N端开始)包括5个区域:PH、TH、SH3、SH2和激酶区。注:图上...
医源资料库;在线期刊;中华医学实践杂志;2006年第5卷第10期Mimicryofaconstitutivelyactivepre–Bcellreceptorinacutelymphoblasticleukemiacells
...theyarerescuedbypre–Bcellreceptor–dependentsurvivalsignals.WepreviouslyshowedthattheBCR-ABL1kinasethatisexpressedinpre–Blymphoblasticleukemiabypassesselectionforpre–Bcellreceptor–dependentsurvivalsignals.InvestigatingpossibleinterferenceofBCR-ABL1withpre–Bcellreceptorsignaling,wefoundtha...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第11期