细胞周期调控因子cyclinD1、p16蛋白表达异常与外阴白色病变发病的关系
...色病变组织34份,其中硬化性苔藓(LS)12份,鳞状上皮增生(SH)18份,SH合并LS4份;另选择正常外阴皮肤组织11份作为对照。应用免疫组化方法检测上述组织中cyclinD1、p16蛋白的表达,并分析其与外阴白色病变发病的关系。结果外阴白...
行业资讯;临床快报;妇科与产科透明质酸钠对兔骨关节炎滑膜iNOS的表达及滑液一氧化氮含量的影响
...学杂志2006Vol.10No.12P.733-7358(武汉)为了观察透明质酸钠(SH)对兔骨关节炎模型滑膜诱导型NO合酶(iNOS)的表达及滑液中NO含量的影响。研究者将16只大耳白兔行单膝前交叉韧带切断术,术后5周将动物随机分为实验组和对照组,实验组...
行业资讯;临床快报;骨科Cognitiveaging,childhoodintelligence,andtheuseoffoodsupplements:possibleinvolvementofn3fattyacids
...eAlzheimer‘sResearchTrust.LJWholdsaWellcomeTrustCareerDevelopmentAward.JMSholdsaHealthFoundationLeadingPracticeThroughResearchAward.IJDisarecipientofaRoyalSocietyofLondonWolfsonResearchMeritAward.3Reprintsnotavailable.AddresscorrespondencetoLJWhalley,DepartmentofMentalHealth,ClinicalResearch...
医源资料库;在线期刊;美国临床营养学杂志;2004年80卷第6期Interferon-InducesFasTraffickingandSensitizationtoApoptosisinVascularSmoothMuscleCellsviaaPIK-andAkt-DependentMechanism
...tosiscancontributetoruptureofmouseplaquesinassociationwithotherstimulisuchashemodynamicstress.6Multipletriggersofapoptosisexistinthecomplexmicroenvironmentoftheplaque,andtheinductionofapoptosisreflectsthebalancebetweendiversepro-andanti-apoptoticsignaling.7However,increasingevidenceimplicatesthetumo...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第6期ActivityandSubcellularTraffickingoftheSodium-CoupledCholineTransporterCHTIsRegulatedAcutelybyPeroxynitrite
...levelsofHC-3bindingandbiotinylatedCHTattheplasmamembrane.Itisnoteworthythatshort-termexposureofcellstoSIN-1acceleratedtherateofinternalizationofCHTfromtheplasmamembrane,butitdidnotalterreturnofCHTbacktothecellsurface.SIN-1didnotdisruptcellmembraneintegrityorcausecelldeath.Thus,theinhibitoryeffectofS...
医源资料库;在线期刊;分子药理学杂志;2008年第70卷第3期ICU病房G+菌谱及其耐药性连续6年监测
...50.3%,其次为表皮葡萄球菌(SE,19.4%)、溶血葡萄球菌(SH,12.6%)。MRSA占SA的87.5%,MRSE占SE的91.2%。体外药敏试验结果显示主要G+菌均呈多重耐药特性,只有万古霉素对G+具有很强抗菌活性,敏感率达100%。结论ICU病房每年G+菌所占...
合作平台;在线期刊;中华医学实践杂志;2005年第4卷第7期;论著Adose-dependentrequirementfortheprolinemotifofCD28incellularandhumoralimmunityrevealedbyatargetedknockinmutant
...unology,2DepartmentofInternalMedicine3DepartmentofPathologyandImmunology,WashingtonUniversitySchoolofMedicine,St.Louis,MO63110ActivationofnaiveTcellsrequirestheintegrationofsignalsthroughtheantigenreceptorandCD28.AlthoughthereisagreementontheimportanceofCD28,thereremainscontroversyonthemechanismbywh...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第9期中药标准品部分中英文对照
...n蒜氨酸 Allocymene βDAlloseβD阿洛糖 Aloeemodin芦荟大黄素 Aloeemodin芦荟大黄素 AloinA芦荟素A DAltroseD阿卓糖 Amentoflavone穗花杉双黄酮 Aminoacephenone氨基苯乙酮 Aminoantipyrin Aminobutyricacid氨基丁酸 Aminoc...
药品天地;专业药学;中药大全;中药指纹图谱天麻首乌片含量测定方法
...补足减失的重量,摇匀,滤过,即得。文献报道的多为以大黄素为指标,如:李瑞莲等采用薄层扫描法,以硅胶G为固定相,正己烷-醋酸乙酯-甲酸(30:10:0.5)为展开剂,测定波长为445nm,参比波长为700nm,测定天麻首乌片中大黄素的...
药品天地;专业药学;实验技术;色谱技术;色谱分析实例Tcellreceptorengagementbypeptide–MHCligandsinducesaconformationalchangeintheCD3complexofthymocytes
...stantdomains.Furthermore,thecrystalstructuresofTCRsboundtovariantpMHCligandshaverevealedonlyminordifferencesinCDRconformationincomparisonwithnominalpeptideligands(12,14).ThesestudiesarguethatconformationalchangesoccurringintheCDRloopsmaynotbecommunicatedtothedistaldomainsoftheTCR–CD3complex.Usinga...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第4期