MinimallyOxidizedLDLOffsetstheApoptoticEffectsofExtensivelyOxidizedLDLandFreeCholesterolinMacrophages
【摘要】Objective-Lipid-loadedmacrophage-derivedfoamcellspopulateatheroscleroticlesionsandproducemanypro-inflammatoryandplaque-destabilizingfactors.Anexcessiveaccumulationofextensivelyoxidizedlow-densitylipoprotein(OxLDL)orfreecholesterol(FC),bothofwhicharebelievedtobemajorlipidcomponentsofmacro...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第5期Macrophage-ExpressedGroupIIASecretoryPhospholipaseA2IncreasesAtheroscleroticLesionFormationinLDLReceptor–DeficientMice
Abstract:TopAbstractIntroductionMethodsResultsDiscussionReferences:Objective—TransgenicmiceexpressinghumangroupIIAsecretoryphospholipaseA2(groupIIAsPLA2)spontaneouslydevelopatheroscleroticlesions.Themechanismforthisproatherogeniceffectislikelymultifactorial,becauseHDL-cholesterolissignificantl...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第2期Maternalthiaminedeficiency:stillaprobleminsomeworldcommunities
RogerFButterworth1FromtheNeuroscienceResearchUnit,CHUM(UniversityofMontreal).2AddressreprintrequeststoRFButterworth,NeuroscienceResearchUnit,DepartmentofMedicine,UniversityofMontreal,HôpitalSaint-LucduCHUM,1058St-DenisStreet,Montreal,QuebecH2X3J4,Canada.E-mail:butterwr{at}medclin.umontreal.ca....
医源资料库;在线期刊;美国临床营养学杂志;2001年74卷第6期LowCirculatingEndogenousSecretoryReceptorforAGEsPredictsCardiovascularMortalityinPatientsWithEnd-StageRenalDisease
【摘要】Objective-Receptorforadvancedglycationend-products(RAGE)isinvolvedindiabeticvascularcomplications.WehaverecentlyshownthatplasmaendogenouslysecretoryRAGE(esRAGE),analternativelysplicedformofRAGE,iscloselyassociatedwithmetabolicsyndromeandatherosclerosis.Here,weevaluatedifplasmaesRAGEisapr...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第1期胚胎干细胞分化为软骨细胞的研究现状与展望
...hui.RedCrossHospital,Guangzhou510220,ChinaAbstract:Embryonicstemcellpossessmultidirectionaldifferentiationcapacityandcandifferentiateintoallsortsofcellsofthreegermlayers,ithasthewidelyuseinthetreatmentoftissuerepair.Recentstudyshowsthat,embryonicstemcellscandifferentiateintocartilagecellsinthee...
医源资料库;在线期刊;中国矫形外科杂志;2009年第17卷第10期MatrixManagement
FromAstraZeneca(C.W.,W.M.,E.H.-C.),RD,MolecularPharmacology,M?lndal;andWallenbergLaboratory(E.H.-C.),GothenburgUniversity,SahlgrenskaAcademy,Sweden.CorrespondencetoDrEvaHurt-Camejo,MolecularPharmacology,RACVGI,AstraZeneca,RD,M?lndal,Sweden,S-43183.E-maileva.hurt-camejo@astrazeneca.comGeometricremode...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第1期注射用头孢替唑的细菌内毒素检查
...,同时用检查用水将细菌内毒素工作标准品同上法稀释(Es)与鲎试剂反应,结果见表1。 结果表明,样品在3.33mg/ml浓度时,Et2.0Es,对鲎试剂有明显的抑制作用。为此,根据MVD的计算值,将样品溶液稀释成1:9.6的浓度(1.67mg/ml...
合作平台;在线期刊;中华医药杂志;2004年第4卷第12期;药物与临床肝脓肿MR诊断(附12例报告)
...可有癌栓也是诊断肝癌的间接证据。AFP升高、有肝炎、肝硬化病史可作为参考。实质性团块状肝脓肿的形态学和MRI信号均难以与恶性肿瘤区别,这类脓肿是诊断和鉴别诊断的难点。但只要以动态增强表现为主要依据,结合平扫信...
合作平台;在线期刊;中华中西医杂志;2004年第5卷第21期;医学影像ClopidogrelImprovesSystemicEndothelialNitricOxideBioavailabilityinPatientsWithCoronaryArteryDisease
【摘要】Background-Plateletstimulationandactivationareknownnotonlyasprerequisiteofclotformationbutareincreasinglyrecognizedasimportantcontributorstoinflammationandvascularinjury.Thepresentstudyinpatientswithsymptomaticcoronarydiseaseinvestigatedwhetherplateletadenosinediphosphatereceptorblockade...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第7期AssociationsBetweenSolubleCD40Ligand,AtherosclerosisRiskFactors,andSubclinicalAtherosclerosis
JamesA.deLemos;AndreasZirlik;UweSch?nbeck;NereaVaro;SabinaA.Murphy;AmitKhera;DarrenK.McGuire;GregStanek;HaoS.Lo;RebeccaNuzzo;DavidA.Morrow;RonaldPeshock;PeterLibbyFromtheDonaldW.ReynoldsCardiovascularClinicalResearchCenter(J.A.d.L.,A.K.,D.K.M.,G.S.,H.S.L.,R.P.),UniversityofTexasSouthwesternMedicalCe...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第10期