RP-HPLC法测定金钱草中槲皮素和山奈素两种黄酮成分的含量
...器与试药瑞士MettlerToledoAG285电子天平;DZF-1真空干燥箱;ZQ-250超声波清洗器;美国安捷伦公司高效液相色谱仪Agilentl100Series,配置四元泵,自动进样器(进样范围为0.1~100μ1),紫外可见光检测器,柱温箱,在线真空脱气泵,色谱工...
药品天地;专业药学;实验技术;色谱技术;色谱论文HIV-1ProteaseandReverse-TranscriptaseMutations:CorrelationswithAntiretroviralTherapyinSubtypeBIsolatesandImplicationsforDrug-ResistanceSurvei
...mparedtheprevalenceofproteaseandreverse-transcriptase(RT)mutationsinHIV-1sequencesfrompersonswithandwithoutprevioustreatmentwithproteaseinhibitors(PIs),nucleosideRTinhibitors(NRTIs),andnonnucleosideRTinhibitors(NNRTIs).Treatment-associatedmutationsinproteaseisolatesfrom5867personsandRTisolatesfrom62...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第15期Findingschizophreniagenes
...narecentmetaanalysisthemedianincidenceratewas15.2per100,000,withthe10%to90%quantilesbetween7.7and43.0per100,000(1).GeneticepidemiologyTheresultsofnumerousfamily,twin,andadoptionstudiesshowconclusivelythatriskofschizophreniaisincreasedamongtherelativesofaffectedindividualsandthatitistheresultlargelyo...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第6期Theflavonoidsquercetinandcatechinsynergisticallyinhibitplateletfunctionbyantagonizingtheintracellularproductionofhydrogenperoxide
PasqualePignatelli,FabioMPulcinelli,AndreaCelestini,LuisaLenti,AndreaGhiselli,PierPaoloGazzanigaandFrancescoVioli1FromtheDepartmentofExperimentalMedicineandPathology,Instituteof1stClinicalMedicine,UniversityLaSapienza,NationalInstituteforNutrition,Rome.2AddressreprintrequeststoPPGazzaniga,Dipartimen...
医源资料库;在线期刊;美国临床营养学杂志;2000年72卷第5期Dlgh1coordinatesactinpolymerization,synapticTcellreceptorandlipidraftaggregation,andeffectorfunctioninTcells
...e-associatedguanylatekinase(MAGUK)familymolecularscaffoldsfunctioninestablishingcellpolarityandorganizingsignaltransducerswithinepithelialcelljunctionsandneuronalsynapses.Here,weelucidatearolefortheMAGUKprotein,Dlgh1,inpolarizedTcellsynapseassemblyandTcellfunction.WefindthatDlgh1translocatestotheimm...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第3期跌打损伤七十四
...宜行血活血。腹痛者,宜下血。瘀肉不溃,或溃而不敛,宜大补气血。若打扑坠堕稍轻,别无瘀血等证,而疼痛不止者,惟和气血,调经脉,其痛自止,更以养气血,健脾胃,则无有不效。亦有痛伤胃气,作呕或不饮食者,以四君子汤加当归,砂仁...
医源资料库;医源图书馆;中医古籍;景岳全书;卷之四十七贤集外科钤下三、SH-2结构域的调节作用
三、SH-2结构域的调节作用 (一)SH-2结构域的结构特点 前已所述,PTKssrc家族包括p59lck和p59fyn,这两个分子的氨基端有三个同源的区域。其中一区域对于豆蔻酸的附着是必需的,豆蔻酸可以通过疏水的相互作用和/或同一...
医源资料库;医源图书馆;教材类;细胞和分子免疫学Tyr702IsanImportantDeterminantofAgonistBindingandDomainClosureoftheLigand-BindingCoreofGluR2
...fullagonists.Bothkainateand(S)-CPW399exhibitedhigherefficacyat(Y702F)GluR2(Q)ithanatwild-typeGluR2(Q)i.Whereasanexcellentcorrelationexistsbetweendomainclosureandefficacyofarangeofagonistsatfull-lengthGluR2determinedbyelectrophysiologyinXenopuslaevisoocytes,adirectcorrelationbetweenagonistinduceddoma...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第3期GeneticAnalysisofFamilialConnectiveTissueAlterationsAssociatedWithCervicalArteryDissectionsSuggestsLocusHeterogeneity
...y(1patientwith8healthyrelatives)indicated2candidateloci.Threegenesweresubsequentlystudiedbysequenceanalysis.Partofthegenomewasalsostudiedbylinkageanalysisin2furtherfamilies.Results—Thegenome-widescaninasinglefamilysuggestedlinkagebetweenthehypotheticalmutationcausingtheconnectivetissuephenotypeand...
医源资料库;在线期刊;中风学杂志;2006年第37卷第7期快速增长的生长激素市场—强者恒强
...比增38.9%。公司目前仅有粉针剂竞争较为激烈,公司正努力补齐产品线:其水剂产品申报生产注册获得受理,长效化技术平台是公司发展重点:PEG化生长激素于2011年10月获临床批件,正进行2期临床试验。PEG化重组人干扰素α2b注射液获临...
医药经济;生物技术;技术要闻