晚期非小细胞肺癌的二线治疗
...从而抑制了细胞的分裂和增殖。在体外人瘤株筛选和动物试验中对多种肿瘤均有效,属于广谱的抗肿瘤植物药。剂量限制性毒性为中性粒细胞减少。体液潴留多见于多疗程化疗后的患者,适量的皮质甾体类激素能预防其发生。泰...
医源资料库;在线期刊;中华中西医杂志;2008年第9卷第10期研究显示药物洗脱支架植入患者的主要临床预后优于金属裸支架
...andre-interventionthanBMSpatientsAstudyshowsthatdrug-elutingstents(DES)havesubstantiallylowerratesofdeath,heartattackandre-interventioninreal-worldpatientscomparedtobare-metalstents(BMS).Theresultsofthestudy,ComparisonofDrug-ElutingVersusBare-MetalStentsonLaterFrequencyofAcuteMyocardialInfarctionand...
行业资讯;临床快报;心胸外科抗HBsAg人IgG表达载体的构建及其在CHO细胞中的表达
...染细胞中存在人IgG的轻链和重链mRNA。 1.9 免疫印迹试验 取抗HBsAg人IgG和标准人IgG进行12%的SDS-PAGE电泳,电转移至纤维膜上,5%脱脂奶粉-PBS4C封闭后,加入HRP-羊抗人IgG(γ链)和HRP-羊抗人Fab(κ链),孵育2h,洗涤后,加入DAB液...
合作平台;医学论文;临床医学与专科论文;检验医学ComputationalIdentificationofKeyBiologicalModulesandTranscriptionFactorsinAcuteLungInjury
...tionandintratrachealLPSproducessignificantlymoreinjurytothelungthaneitherinsultalone.WeusedglobalgeneontologyanalysistodetermineoverrepresentedbiologicalmodulesandcomputationaltranscriptionfactoranalysistoidentifyputativeregulatoryfactorsinvolvedinthismodelofALI.Results:Byintegratingexpressionprofil...
医源资料库;在线期刊;美国呼吸和危急护理医学;2006年第173卷第6期Sorsbyfundusdystrophypresentingwithchoroidalneovascularisationshowinggoodresponsetosteroidtreatment
...SMDownesOxfordEyeHospital,RadcliffeInfirmary,WoodstockRoad,OxfordOX26HE,UK;susan.downes@orh.nhs.ukAcceptedforpublication15May2003Keywords:choroidalneovascularisation;Sorsbyfundusdystrophy;steroidsSorsbyfundusdystrophy(SFD)isadominantlyinheritedmaculardystrophyinwhichbilateralcentralvisuallossoccursi...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第3期ScreeningforObstructiveSleepApneainStrokePatients
...ecovery,butwhetherscreeningforOSAandtreatmentbycontinuouspositiveairwaypressure(CPAP)improvesneurologicaloutcomeisunknown.Weusedacost-effectivenessmodeltoestimatethemagnitudeofbenefitthatwouldbenecessarytomakepolysomnography(PSG)andOSAtreatmentcost-effectiveinstrokepatients.Methods—Adecisiontreemo...
医源资料库;在线期刊;中风学杂志;2005年第36卷第6期SrcFamilyKinaseInhibitorsBlockAmphiregulin-MediatedAutocrineErbBSignalinginNormalHumanKeratinocytes
...ealthSystem,AnnArbor,Michigan(J.T.E.)Abstractc-Srcpotentiatesproliferation,survival,andinvasivenessinresponsetoepidermalgrowthfactor(EGF)inhumanmammarycarcinomacells.Tyrosine(Tyr)845ofErbB1isphosphorylatedbySrcandhasbeenimplicatedincontrolofmalignantbehavior.Althoughseverallinesofevidencealsosuggest...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第4期Oligofructose-supplementedinfantcereal:2randomized,blinded,community-basedtrialsinPeruvianinfants
...tsCompany,Fremont,MI(FCandCE);andMassachusettsGeneralHospital,Boston(REK).2SupportedbyGerberProductsCompany.3AddressreprintrequeststoREKleinman,PediatricGastrointestinal/NutritionUnit,MassachusettsGeneralHospitalforChildren,55FruitStreet,Boston,MA02114.E-mail:rkleinman{at}partners.org.ABSTRACTBackgr...
医源资料库;在线期刊;美国临床营养学杂志;2003年77卷第4期ANewRoleforGlucocorticoidsinSepticShockBalancingtheImmuneResponse
...UniversityofMunichMunich,Germany:Glucocorticoidsarethemostimportantimmunosuppressiveagentsinmedicine;theyareanestablishedtherapyforagreatvarietyofchronicinflammatorydiseasesaswellasintransplantationmedicine.Inacuteinflammation,particularlysepsisand/orsepticshock,theuseofhigh-dosecorticosteroidshas...
医源资料库;在线期刊;美国呼吸和危急护理医学;2003年第167卷第4期MMTVEnvencodesanITAMresponsiblefortransformationofmammaryepithelialcellsinthree-dimensionalculture
...tif(ITAM)-containingsignalingproteinsisnormallyrestrictedtohematopoietictissues.ThebasalactivityofITAM-containingproteinsismediatedthroughnegativeregulationbycoreceptorsrestrictedtohematopoietictissues.WehaveidentifiedanITAMsignalingdomainencodedwithintheenvgeneofmurinemammarytumorvirus(MMTV).Three-...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第3期