AntibodiestoVoltage-GatedCalciumChannelsinChildrenwithFalciparumMalaria
...iacanaffectthecentralnervoussystem(CNS),causingneurologicaldysfunctionandsequelae.Thepathophysiologyofthesecomplicationsiscurrentlyverypoorlyunderstood.ProductionofautoantibodieshasfrequentlybeenreportedasaconsequenceofinfectionwithPlasmodiumfalciparum.However,atpresent,thepresenceofantibodiestocomp...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第1期小鼠趋化素样因子超家族成员1cDNA的克隆化和鉴定
...溯到小鼠,可以利用小鼠模型研究CKLFSF1的功能。 ChengShanhong,WangLu BeijingUniversity,Beijing100083. 【Abstract】ObjectiveToinvestigatethegeneevolutionofhumanCKLFSF1andprovideabasisfortheaniˉmalexperimentalresearchofit,thisarticleconductedtheexperimentofclon...
合作平台;在线期刊;中华医学研究杂志;2004年第4卷第9期;论著LungVolumeReductionSurgeryforEmphysema:CorrelationofCTandV/QImagingwithPhysiologicMechanismsofImprovementinLungFunction1
...A02115.Fromthe2000RSNAscientificassembly.ReceivedFebruary14,2001;revisionrequestedMarch20;revisionreceivedJune8;acceptedJuly5. ABSTRACT:TopABSTRACTINTRODUCTIONMATERIALSANDMETHODSRESULTSDISCUSSIONREFERENCES:PURPOSE:Tocomparetherelationshipbetweencomputer-derivedandvisuallyassessedventilation-pe...
医源资料库;在线期刊;放射学杂志;2003年1月第226卷第2期2-3统计学原理在遗传学中的应用
...传学的一个重要理论基础。 概率有两个定则:(1)p+q=1,也就是说一件物若有两方面,那么它们发生的可能性总和等于1。如足球裁判掷硬币,要么是正,要么是反,可能性各为50%,总和为1。(2)0≤p≤1,当概率(P)=1时,...
医源资料库;医源图书馆;教材类;遗传学RoscovitineTriggersExcitotoxicityinCulturedGranuleNeuronsbyEnhancingGlutamateRelease
...vitineenhancesthecouplingbetweentetrodotoxin-sensitiveactionpotentialsandP/Q-typevoltage-dependentcalciumchannels(VDCCs),therebyconvertingthissurvivalprogramtoexcitotoxicityofsynapticorigin.Therefore,roscovitine-triggerednecrosisrequiresspontaneousNa+-basedactionpotentials(tetrodotoxininhibits,(±)-...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第5期骨髓间充质干细胞治疗脑梗死的研究进展
...胞的表面标志,而不表达造血干细胞的表面标志。BMSCs对SH2、SH3、SH4、CD29、CD44、CD71、CD90、CD105、CD166等抗体呈阳性反应,对CD11b、CD14、CD31、CD34、CD45、CD133等则呈阴性[7~9]。其中SH2、SH3、SH4随着干细胞的分化而...
医源资料库;在线期刊;滨州医学院学报;2009年第32卷第1期IdentificationofEssentialHistidineandCysteineResiduesoftheH+/OrganicCationAntiporterMultidrugandToxinExtrusion(MATE)
...on1(MATE1)hasbeenisolatedasanH+/organiccationantiporterlocatedattherenalbrush-bordermembranes.Previousstudiesusingratrenalbrush-bordermembranevesiclesindicatedthatcysteineandhistidineresiduesplayedcriticalrolesinH+/organiccationantiportactivity.Inthepresentstudy,essentialhistidineandcysteineresidues...
医源资料库;在线期刊;分子药理学杂志;2007年第69卷第6期Interferon-InducesFasTraffickingandSensitizationtoApoptosisinVascularSmoothMuscleCellsviaaPIK-andAkt-DependentMechanism
...tosiscancontributetoruptureofmouseplaquesinassociationwithotherstimulisuchashemodynamicstress.6Multipletriggersofapoptosisexistinthecomplexmicroenvironmentoftheplaque,andtheinductionofapoptosisreflectsthebalancebetweendiversepro-andanti-apoptoticsignaling.7However,increasingevidenceimplicatesthetumo...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第6期n-3Fattyacidsupplementsinrheumatoidarthritis
...ndAvenue,Albany,NY12208.ABSTRACTIngestionofdietarysupplementsofn-3fattyacidshasbeenconsistentlyshowntoreduceboththenumberoftenderjointsonphysicalexaminationandtheamountofmorningstiffnessinpatientswithrheumatoidarthritis.Inthesecases,supplementswereconsumeddailyinadditiontobackgroundmedicationsandthe...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第1期Caspasesandcalpainareindependentmediatorsofcisplatin-inducedendothelialcellnecrosis
...ainingwith50µMcisplatinat24hwasreducedbyeitherthepancaspaseinhibitor,Q-VD-OPH,orthecalpaininhibitor,PD-150606.Calpaininhibitorhadnoeffectoncaspase-3-likeactivity.Inconclusion,incisplatin-treatedendothelialcells,caspases,themajormediatorsofapoptosis,canalsocausenecrosis.Acalpaininhibitorprotect...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第9期