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AlteredbloodpressureresponsesandnormalcardiacphenotypeinACE2-nullmice
...egeneratedmicewithtargeteddisruptionoftheAce2gene.ACE2-deficientmicewereviable,fertile,andlackedanygrossstructuralabnormalities.WefoundnormalcardiacdimensionsandfunctioninACE2-deficientanimalswithmixedorinbredgeneticbackgrounds.OntheC57BL/6background,ACE2deficiencywasassociatedwithamodestincreaseinb...
医源资料库；在线期刊；临床研究杂志；2006年第116卷第8期 -
T细胞疫苗抗同种心肌移植排斥反应的实验研究
...ConclusionTheresultsofthestudiespreliminarydemon-strate:Tcellvaccinationenabletoallomycardiumoftransplantationtosurvivelongerandcalculateditwouldprovideanovelwayforinhibitingtransplantationrejection. 【Keywords】allomyocardium;transplantationrejection;Tcellvaccination 机体免疫系统...
合作平台；在线期刊；中华医药杂志；2005年第5卷第6期；论著 -
Resveratrol(trans-3,5,4‘-Trihydroxystilbene)AmelioratesExperimentalAllergicEncephalomyelitis,PrimarilyviaInductionofApoptosisinTCellsInvolvingA
...oanessentialcomponentofKo-jo-kon,anorientalmedicineusedtotreatdiseasesofthebloodvessels,heart(Celottietal.,1996;Soleasetal.,1997),andliver(Soleasetal.,1997).Resveratrolhasbeenthefocusofrecentstudiesofitspharmacologicalandbeneficialpropertiesonawiderangeofdiseases,includingneurological,hepatic,cardio...
医源资料库；在线期刊；分子药理学杂志；2007年第69卷第12期 -
NonendothelialMesenchymalCell-DerivedMCP-1IsRequiredforFGF-2-MediatedTherapeuticNeovascularization
...genesishavenotbeenwellelucidated.MethodsandResults-Usingmurinemodelsoffibroblastgrowthfactor-2(FGF-2)-mediatedtherapeuticneovascularization,wehereshowthatFGF-2targetsnonendothelialmesenchymalcells(NEMCs)enhancingbothangiogenic(vascularendothelialgrowthfactor)andarteriogenic(MCP-1)signalsviaindepende...
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第11期 -
QuantitativeTraitLociAnalysisforPlasmaHDL-CholesterolConcentrationsandAtherosclerosisSusceptibilityBetweenInbredMouseStrainsC57BL/6Jand129S1/
...600MainStreet,BarHarbor,ME04609.E-mailbjp@jax.orgAbstractObjective—TheC57BL/6(B6)and129mouseinbredstrainsdiffermarkedlyinplasmaHDL-cholesterolconcentrationsandatherosclerosissusceptibilityafterahigh-fatdietconsumption.Toidentifylocicontrollingthesetraits,weperformedquantitativetraitloci(QTL)analys...
医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第1期 -
女性青少年自我控制能力及其相关因素分析
【摘要】目的研究女性青少年自我控制能力及其相关影响因素，为减少青少年相关行为问题的干预研究提供依据。方法采用便利样本抽样方法，对北京、济南、广州妇幼保健机构青少年门诊就诊的1391名10～24岁未婚女性青少年进...
医源资料库；在线期刊；中国学校卫生；2008年第28卷第3期 -
营养所等从旋覆花中发现靶向NF-κB信号通路抗癌化合物
...a,NHL，约占总淋巴瘤病例90%）两大类，其中Burkitt淋巴瘤（BL）是一种来源于未分化B淋巴细胞的NHL（B-NHL），恶性程度极高。同时，NHL中几乎所有的B细胞肿瘤均可见于AIDS患者，大多数为高度恶性淋巴瘤。在我国，近年来淋巴瘤的...
行业资讯；临床快报；肿瘤相关 -
CytosolicrecognitionofflagellinbymousemacrophagesrestrictsLegionellapneumophilainfection
...totriggerthemacrophageresponsefromperforatedphagosomes:onceheatedtodisassemblefilaments,flagellintriggeredcelldeathbutnativeflagellarpreparationsdidnot.FlagellinmadeL.pneumophilavulnerabletoinnateimmunemechanismsbecauseNaip5+macrophagesrestrictedthegrowthofvirulentmicrobes,butflagellinmutantsreplica...
医源资料库；在线期刊；实验医学杂志；2006年第203卷第4期 -
TCellAccumulationinBCellFolliclesIsRegulatedbyDendriticCellsandIsIndependentofBCellActivation
...liclesinimmunizedOX40-deficientmice. KeyWords:Tlymphocytemigration•Blymphocytes•OX40•CXCR5•lymphoidfollicles IntroductionTopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferencesT-dependenthumoralimmuneresponsesarecharacterizedbythedevelopmentofgerminalcenters...
医源资料库；在线期刊；实验医学杂志；2003年第197卷第2期 -
TCellAccumulationinBCellFolliclesIsRegulatedbyDendriticCellsandIsIndependentofBCellActivation
...liclesinimmunizedOX40-deficientmice. KeyWords:Tlymphocytemigration•Blymphocytes•OX40•CXCR5•lymphoidfollicles IntroductionTopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferencesT-dependenthumoralimmuneresponsesarecharacterizedbythedevelopmentofgerminalcenters...
医源资料库；在线期刊；美国病理学杂志；2003年第162卷第2期