Standardizedthighmuscleareameasuredbycomputedaxialtomographyasanalternatemusclemassindexfornutritionalassessmentofhemodialysispatients
...epresentsthelargestproteinpoolinthebody,isimportantfornutritionalassessmentbutisdifficulttoachievewithconventionalmethodsinhemodialysispatients.Objective:Wemeasuredthecross-sectionalareaofthethighoccupiedbymusclebyusingcomputedtomographyandcomparedthiswithothermusclemassindicators.Design:Thighmuscle...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第2期IdentificationoftheFirstSyntheticSteroidogenicFactor1InverseAgonists:PharmacologicalModulationofSteroidogenicEnzymes
...ocrinefunction.Firstidentifiedasatranscriptionfactorwithlimitedtissuedistribution,itisfoundprimarilyinsteroidogenictissues(Morohashietal.,1992).Assuch,SF-1ishighlyexpressedinthetestesandovariesbuthasalsobeenreportedtobepresentinothertissues,includingtheskin,spleen,andbrain(Ikedaetal.,1994).SF-1nullm...
医源资料库;在线期刊;分子药理学杂志;2008年第70卷第3期CoimmunoprecipitationofUDP-GlucuronosyltransferaseIsoformsandCytochromeP4503A4
...phaseIandIIenzymeswouldpermitthereactionstoproceedmoreefficientlyinthecell,butthisconcepthasnotbeendemonstratedinvitro.ResearchusingP450shasdemonstratedthatcoexpressedbaculovirusP450isoformscanalteroneanother‘scatalyticactivity(Cawleyetal.,1995;Tanetal.,1997;Yamazakietal.,1997;Backesetal.,1998).Se...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第1期MultiplexPCRforDirectDetectionofShigaToxigenicEscherichiacoliStrainsProducingtheNovelSubtilaseCytotoxin
...gatoxigenicEscherichiacoli(STEC)strains.Thispotentiallylethaltoxinmaycontributetoseveregastrointestinalandsystemicdiseaseinhumans.InthisstudywehavedevelopedatrivalentPCRassayforthedetectionofthenoveltoxinAsubunitgenesubA,aswellasstx1andstx2.Thethreeprimerpairsusedintheassaydonotinterferewitheachothe...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第6期S-NitrosylatingAgents:ANovelClassofCompoundsThatIncreaseCysticFibrosisTransmembraneConductanceRegulatorExpressionandMaturationinEpithelialC
...amyltranspeptidasetoincreaseCFTRmaturation;4)surprisingly,expression—butnotS-nitrosylation—ofcysteinestringproteins(Csp)1and2isincreasedbyGSNO;5)theeffectofGSNOtoincreasefullmaturationofwild-typeCFTRisinhibitedbyCspsilencing(si)RNA;6)proteinsrelevanttoCFTRtraffickingareSNO-modified,andSN...
医源资料库;在线期刊;分子药理学杂志;2006年第68卷第10期DevelopmentandValidationoftheStrokeActionTest
...rsonmayknowthata911callisthebestresponsetostrokewhenthediagnosisisprovided,butmaynotknowtocall911whenastrokesymptompresents.11Allofthesefactorsconfoundinterpretationofdatathattheassessmentsproduce.ThepurposeofthisstudywastodevelopandevaluatetheStrokeActionTest(STAT),anewwritteninstrumentwhoseitemsre...
医源资料库;在线期刊;中风学杂志;2005年第36卷第5期ClusterRandomizedPilotControlledTrialofanOccupationalTherapyInterventionforResidentsWithStrokeinUKCareHomes
...s)orcontrol(6homes,55residents).Occupationaltherapywasprovidedtoindividualsbutincludedcarereducation.Thecontrolgroupreceivedusualcare.Assessmentsweremadeatbaseline,postintervention(3months)andat6-monthstoestimatechangeusingtheBarthelActivityofDailyLivingIndex(BI)scores,“poorglobaloutcome“,(defin...
医源资料库;在线期刊;中风学杂志;2006年第37卷第9期TheepidemiologyofoculartraumainruralNepal
...existsbetweenthiscommunityandtheNNIPSProject,aswellasthe4–6hourdistancebybustootherspecialtyeyecare,itislikelythattheclinicevaluatedalmostallseverecasesofoculartraumainthe30VDCs.Traumawasdefinedbypatientorparentalreportofrecenteyeinjuryforwhichcarewassought.Patientinterviewsandeyeexaminationswerec...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第4期初中生近视进展与近距离工作眼动参数的相关性研究
...40cm,0.8的单行垂直视标,在左眼前放置垂直分离棱镜(6△BU),右眼前放置水平分离棱镜(12△BI),采用VonGrafe法测量近距水平隐斜[4]。外隐斜记为负值,内隐斜记为正值。 1.2.2AC/A测量 采用梯度法(GradientMethod),即完成近...
医源资料库;在线期刊;中国学校卫生;2008年第28卷第12期EfficacyofH5InfluenzaVaccinesProducedbyReverseGeneticsinaLethalMouseModel
...ineagainstH5N2virusesofNorthAmericanlineagehasbeenusedinMexicosince1995[6],butavianvaccinesagainstEurasianH5N1virusesarenotcommerciallyproduced.Theprotectionprovidedbyinfluenzavaccinesisbasedontheinductionofvirus-neutralizingantibodies,mainlyagainsthemagglutinin(HA).TheHAgenesofhighlypathogenicAsian...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第8期