ASystematicReviewandMeta-AnalysisofStatinTherapyinChildrenWithFamilialHypercholesterolemia
...placebo-treatedchildrenwithrespecttotheoccurrenceofadverseevents(RR0.99;95%CI:0.79to1.25),sexualdevelopment(RRofadvancing1stageinTannerclassification0.96;95%CI:0.79to1.17),muscletoxicity(RRofCK10timestheupperlimitofnormal1.38;95%CI:0.18to10.82),orlivertoxicity(RRof3timestheULNforASAT0.98;95%CI:0.23t...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第8期WheezePhenotypesandLungFunctioninPreschoolChildren
...odwheezingillness.Withinthecontextofabirthcohortstudy,weinvestigatedtheassociationbetweenpreschoollungfunctionandphenotypesofwheeze.Fromparentallyreportedhistoryofwheeze(interviewer-administeredquestionnaire,age3and5years),childrenwereclassifiedasneverwheezers,transientearlywheezers,late-onsetwheeze...
医源资料库;在线期刊;美国呼吸和危急护理医学;2005年第171卷第2期SchistosomiasisandHIV-1InfectioninRuralZimbabwe:ImplicationsofCoinfectionforExcretionofEggs
...gy,UniversityofZimbabwe,Harare,ZimbabweLondonSchoolofHygieneandTropicalMedicine,London,UnitedKingdomDepartmentofParasitology,LeidenUniversityMedicalCenter,Leiden,TheNetherlandsBackground.StunteddevelopmentandreducedfecundityofSchistosomaparasitesinimmunodeficientmiceandtheimpairedabilityofhumanimmun...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第8期Fruitandvegetableconsumption,intakeofmicronutrients,andbenignprostatichyperplasiainUSmen
SabineRohrmann,EdwardGiovannucci,WalterCWillettandElizabethAPlatz1FromtheDepartmentofEpidemiology,JohnsHopkinsBloombergSchoolofPublicHealth,Baltimore,MD(SRandEAP);theDivisionofClinicalEpidemiology,GermanCancerResearchCenter,Heidelberg,Germany(SR);theDepartmentsofNutritionandEpidemiology,HarvardSchoo...
医源资料库;在线期刊;美国临床营养学杂志;2007年85卷第2期监测阿达木单抗浓度可预测IBD患者临床反应
...4.9mcg/mL和AAA>10ng/mL)。 在ADA优化后,A组有29.2%(95%CI,15~43)的患者达到临床缓解,B组有67%(95%CI,45~82)和C组有12%(95%CI,0~28)。优化后平均复发时间B组(15个月)优于A组(5个月)和C组(4个月;组间P<0.01)。 ...
药品天地;专业药学;药学研究CoronaryAtherosclerosisandAlcoholConsumption
【摘要】Objective-Moderatealcoholconsumptionisassociatedwithreducedcardiovasculardisease(CVD)risk.Whetherthisprotectionisbasedonalesserdegreeofcoronaryatherosclerosishasnotbeenestablished.MethodsandResults-Westudied1676menand465womenconsecutivelyundergoingcoronaryangiography.Ascore(ATS)wascalcul...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第7期Potentialroleofdietaryn3fattyacidsinthepreventionofdementiaandmaculardegeneration
...onAgingatTuftsUniversity,Boston,MA2Presentedatthesymposium“n3FattyAcids:RecommendationsforTherapeuticsandPrevention,“heldattheInstituteofHumanNutrition,ColumbiaUniversity,NewYork,NY,21May20053SupportedbyUSDA581950-9-001and53-3K06-5-10andcontractHV-83-03fromtheNationalInstitutesofHealth,4Re...
医源资料库;在线期刊;美国临床营养学杂志;2006年83卷第6期NRAMP1基因INT4和3UTR位点多态性与肺结核易感性的研究
...白1(NRAMP1)基因INT4和3‘UTR位点多态性与中国北方汉族成人肺结核发病的关系。研究者采用1:1配对的病例对照研究设计,用聚合酶链反应-限制性片段长度多态性分析方法检测NRAMP1基因中INT4和3‘UTR两个多态性位点,对与肺结核相关...
行业资讯;临床快报;流行病与传染病BacterialVaginosisandSusceptibilitytoHIVInfectioninSouthAfricanWomen:ANestedCase-ControlStudy
InfectiousDiseasesEpidemiologyUnit,SchoolofPublicHealthandFamilyMedicineDepartmentofObstetricsandGynaecology,UniversityofCapeTown,CapeTown,SouthAfricaDepartmentofEpidemiology,MailmanSchoolofPublicHealthDepartmentofPathologyandGertrudeH.SergievskyCenter,CollegeofPhysiciansandSurgeons,ColumbiaUniversi...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第20期Cell-LevelPharmacokineticModelofGranulocyteColony-StimulatingFactor:ImplicationsforLigandLifetimeandPotencyinVivo
...dMethodsResultsDiscussionReferencesThecytokinegranulocytecolony-stimulatingfactor(GCSF)isofgreatclinicalimportance,withprimaryapplicationtorapidlyelevatetheperipheralneutrophillevelsofchemotherapypatientsthroughacceleratedgranulopoiesis.However,thesematurebloodstreamneutrophilsexpresstheGCSFreceptor...
医源资料库;在线期刊;分子药理学杂志;2003年第63卷第1期