EffectofPeroxisomeProliferator–ActivatedReceptor-and-ActivatorsonVascularRemodelinginEndothelin-DependentHypertension
...dofOrmsbeeandRyan.13Inbrief,maleSprague-Dawleyrats(CharlesRiver,StConstant,Québec,Canada)weighing225gwereunilaterallynephrectomizedundersodiumpentobarbitalanesthesia(40mg/kg).SiliconerubberimpregnatedwithDOCA(200mgperrat,n=6)wasimplantedsubcutaneously,andratswereoffered1%salinetodrink.Controlrats(U...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第1期MolecularSignaturesDeterminingCoronaryArteryandSaphenousVeinSmoothMuscleCellPhenotypes
...s.6,7However,themolecularfeaturesthatdeterminethedifferentSMCsubtypesanduniquefunctionalresponsesarestillpoorlyelucidated.Inthisstudy,weusedmicroarraygeneexpressionprofilingtoidentifytheuniquemolecularsignaturesthatdistinguishhumanvascularSMCsubtypesfromsaphenousvein(SVSM)andcoronaryartery(CASM),and...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第5期PrognosticUtilityofLipoprotein-AssociatedPhospholipaseA2forCardiovascularOutcomesinPatientsWithStableCoronaryArteryDisease
...atincludedhs-CRP.Afteradjustmentforbaselinecharacteristics,patientsinhigherquartilesofLp-PLA2remainedatsignificantlygreaterriskforthecompositeofcardiovasculardeath,MI,coronaryrevascularization,UA,orstroke(P0.001fortrend,adjHR1.41,95%CI1.17to1.70,forpatientsin4thversus1stquartile).Theassociationwasco...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第11期RegulationofrenalNaPi-2expressionandtubularphosphatereabsorptionbygrowthhormoneinthejuvenilerat
...cedgrowthratewasusedasanindicatorofthesuppressionofpulsatileGHrelease.Theacquisitionofthedataforthethreeexperimentalgroupswasperformedinparallel.Thedatafortheadultandjuvenileratshavebeenpreviouslypublished(37).ThismanuscriptincludespartsofthepreviouslypublisheddataascontrolstocontrasttheeffectsofGHs...
医源资料库;在线期刊;美国生理学杂志;2004年第287卷第7期EnhancementofAntimycobacterialActivityofMacrophagesbyStabilizationofInnerMitochondrialMembranePotential
...ociatedwithkillingofintracellularmycobacteriaandmightalsobenefitthehostbysequesteringbacilliinapoptoticbodiesforsubsequentexpediteduptakebyphagocytes[36].Thiswouldpreventtheextracellularspreadofinfectionandprotectsurroundingtissuesfromtheharmfuleffectsofcellularnecrosis.Macrophagesinfectedwithmycoba...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第8期Proapoptotic,Antimigratory,Antiproliferative,andAntiangiogenicEffectsofCommercialC-ReactiveProteinonVariousHumanEndothelialCellTypesInVitro
...alCRP,dialyzedcommercialCRP(dCRP)toremoveazide,andsodiumazide(NaN3)aloneatequivalentconcentrationstotheundialyzedpreparationweretestedatvaryingconcentrationsonhumanumbilicalveinendothelialcells(HUVEC),circulatingendothelialoutgrowthcells(EOC),andendothelialprogenitorcells(EPC)invitro.CRPandNaN3alone...
医源资料库;在线期刊;循环研究杂志;2005年第95卷第7期海马区神经干细胞分化增殖及其对中枢系统疾病的治疗
...力,这些新形成的神经细胞参与海马依赖性的记忆过程。Qu等[11]把神经球状态的未分化人NSC(HNSCs)移植到青年和老年大鼠侧脑室,30d后,移植的HNSCs分化成神经细胞和星形胶质细胞,这些细胞以非常有序的模式迁移到海马和...
医源资料库;在线期刊;中国热带医学杂志;2006年第6卷第5期Directcorrelationofglutathioneandascorbateandtheirdependenceonageandseasoninhumanlymphocytes
...FoundationandTF,HP,andJRWarescholarsoftheFondsdelaRechercheenSantéduQuébec.3AddressreprintrequeststoJRWagner,CentredeRecherche,InstitutUniversitairedeGériatriedeSherbrooke,Pavillond‘Youville,1036rueBelvédèreSud,Sherbrooke,Québec,CanadaJ1H4C4.E-mail:rwagner...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第5期Short-termproteinandenergysupplementationactivatesnitrogenkineticsandaccretioninpoorlynourishedelderlysubjects
...Mahé,PaulValensi,ClaireGaudichon,FrançoiseFerrière,JacquesRautureauandDanielTomé1FromtheInstitutNationaldelaRechercheAgronomique(INRA),UnitédeNutritionHumaineetdePhysiologieIntestinale,InstitutNationalAgronomiqueParis-Grignon(INAPG),Paris;theServicedeGastro-ent&eac...
医源资料库;在线期刊;美国临床营养学杂志;2000年71卷第5期SystemToAssessGenomeSequencingNeedsforViralProteinDiagnosticsandTherapeutics
...x808,L-174,Livermore,California94551ABSTRACTComputationalanalysesofgenomesequencesmayelucidateproteinsignaturesuniquetoatargetpathogen.WeconstructedaProteinSignaturePipelinetoguidetheselectionofshortpeptidesequencestoserveastargetsfordetectionandtherapeutics.Insilicoidentificationofgoodtargetpeptide...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第4期