立体心电图诊断右心室肥大
...图;优越性 传统ECG诊断心室肥大,主要是依据胸导联QRS波群电压增高,其敏感性和准确性均受多种原因所限。特别是右心室肥大的诊断,由于导联位置的局限,加上左室电势大于右室,往往右室肥大得不到及时准确的诊断。...
医源资料库;在线期刊;中华实用医药杂志;2006年第6卷第1期C1q-DeficiencyIsNeuroprotectiveAgainstHypoxic-IschemicBrainInjuryinNeonatalMice
...emicbraininjuryinneonatalmice.Methods—Hypoxia-ischemia(HI)wasproducedinC1q–/–andwild-type(WT)neonatalmice.At24hoursafterHI,neonatalmousereflexperformanceandcerebralinfarctvolumewereassessed.Long-termoutcomesweremeasuredbywater-mazeperformanceanddegreeofcerebralatrophyat7to8weeksafterHI.Activat...
医源资料库;在线期刊;中风学杂志;2005年第36卷第10期AntibodiestoVoltage-GatedCalciumChannelsinChildrenwithFalciparumMalaria
...iacanaffectthecentralnervoussystem(CNS),causingneurologicaldysfunctionandsequelae.Thepathophysiologyofthesecomplicationsiscurrentlyverypoorlyunderstood.ProductionofautoantibodieshasfrequentlybeenreportedasaconsequenceofinfectionwithPlasmodiumfalciparum.However,atpresent,thepresenceofantibodiestocomp...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第1期MastocytosisinmiceexpressinghumanKitreceptorwiththeactivatingAsp816Valmutation
...stituteforCancer,13009Marseille,France3CentreNationaldelaRechercheScientifiqueUMR8147,CellularandMolecularHematologyLaboratory,PharmacyUniversity,75006Paris,France4CellularandMolecularAllergologyLaboratory,PasteurInstitute,75015Paris,France5ImmunologyLaboratory,RangueilUniversityHospital,31000Toulou...
医源资料库;在线期刊;实验医学杂志;2005年第202卷第12期ActivityoftherenalNa+-K+-2Cl-cotransporterisreducedbymutagenesisofN-glycosylationsites:roleforproteinsurfacechargeinCl-transport
...rgetforloopdiureticsandthecauseoftypeIBartter‘ssyndrome.BecausetheNKCC2sequencecontainstwoputativeN-linkedglycosylationsites,oneofwhichisconservedwiththerenalNa+-Cl-cotransporterinwhichglycosylationaffectsthiazideaffinity,weassessedtheroleofglycosylationonNKCC2functionalproperties.One(N442QorN452Q...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第5期RapidandSensitiveDetectionofSevereAcuteRespiratorySyndromeCoronavirusbyRollingCircleAmplification
...A),wewereabletoachievesensitivedetectionlevelsofSARS-CoVRNAinbothsolidandliquidphases.ThemainadvantageofRCAisthatitcanbeperformedunderisothermalconditionswithminimalreagentsandavoidsthegenerationoffalse-positiveresults,aproblemthatisfrequentlyencounteredinPCR-basedassays.Furthermore,theRCAtechnology...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第5期非典型急性心肌梗死的临床分析
...梗塞3例。(3)心电图表现不典型12例,其中室颤2例,无Q波性MI4例,CLBBB合并前壁AMI1例,MI原位再梗死3例,复合性AMI2例。1.4统计学处理率的比较采用χ2检验。2结果住院期间病死率A组死亡17例(30.4%);B组死亡14例(9.6%)(χ2=15.44...
合作平台;在线期刊;中华现代中西医杂志;2004年第2卷第1期;临床医学PathogenicRoleforVirus-SpecificCDTCellsinMicewithCoronavirus-InducedAcuteEncephalitis
...edarecombinantJHMVwithmutationsintheimmunodominantCD4T-cellepitope(rJ.MY135Q).InfectionofnaïveB6micewiththisvirusresultedinmilddiseasewithnomortality.However,introductionofaCD4T-cellepitopefromListeriamonocytogenesintorJ.MY135Qgeneratedahighlyvirulentvirus.Thedecreaseindiseaseseveritywasnotduet...
医源资料库;在线期刊;美国病理学杂志;2006年第168卷第7期GlycosylationoftheosmoresponsivetransientreceptorpotentialchannelTRPV4onAsn-651influencesmembranetrafficking
...potential(TRP)channelTRPV4.MutationofthisresiduefromAsntoGln(i.e.,TRPV4N651Q)resultedinlossofaslowermigratingbandonanti-TRPV4immunoblotsandamarkedreductioninlectin-precipitableTRPV4immunoreactivity.HEK293cellstransientlytransfectedwiththemutantTRPV4N651Qexhibitedincreasedcalciumentryinresponsetohypo...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第5期MolecularEpidemiologyofCalicivirusesDetectedinSporadicandOutbreakCasesofGastroenteritisinFrancefromDecember1998toFebruary2004
LaboratoiredeVirologieandCNRdesVirusEnteriques,EA562,CHUdeDijonandUFRsMedecine-Pharmacie,DijonLaboratoiredeMicrobiologie,IFREMER,NantesInstitutNationaldeVeilleSanitaire,ParisInstitutNationaldelaSanteetdelaRechercheMedicaleUniteU444,Paris,FranceABSTRACTWecompiledsequenceandepidemiologicaldatafrom172c...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第9期