不同病理类型的2型糖尿病肾病患者临床特征比较

...果（1）NOD组患者糖尿病病程较DIF组患者长[（122．0±8．1vs56．0±7．8）个月，P〈0．01]，高血压病程较DIF组患者短[（49．0±10．3vs84．0±12．6）个月，P〈0．05]，BMI较DIF组患者低[（24．1±0．4vs26．1±0．4）kg／m^2，P〈0．01]，尿蛋白水...

CerebrovascularResponsetoCarbonDioxideinPatientswithCongestiveHeartFailure

...per-andhypocapnia)waslowerinpatientswithapneathaninthecontrolgroup(1.8±0.2vs.2.5±0.2%/mmHg,p0.05),mainlyduetotheprominentreductionofcerebrovascularreactivitytohypocapnia(1.2±0.3vs.2.2±0.1%/mmHg,p0.05).Similarly,brainbloodflowdemonstratedasmallersurgeaftera20-secondbreath-hold(peakvelocity,119±4...

NAs治疗慢性乙肝：双药联合Vs单药治疗

根据一项临床试验结果称，与克拉夫定单药治疗相比，慢性乙肝病毒感染患者经克拉夫定和阿德福韦联合治疗后，表现出良好的耐药谱。研究详情研究人员在韩国进行了一项随机非盲临床试验，对57例慢性乙型肝炎病毒（HBV）感...

简述新型抗精神病药阿立哌唑

...7%和9%。与安慰剂相比，最常见的不良反应有：头痛（32%vs25%）、焦虑（25%vs24%）、失眠（24%vs19%）、恶心（14%vs10%）、呕吐（12%vs7%）、嗜睡（11%vs8%）、头昏目眩（11%vs7%）、坐立不安（10%vs7%）和便秘（10%vs8%）。Carson等为期26周的...

CHARM-Overall研究

...emortalityreductionincandesartanandplacebogroupsofborderlinesignificance(23vs.25%,hazardratio0.91,95%CI0.83–1.00,P=0.055)Cardiovasculardeathsignificantlyreduced(18.2vs.20.3%,P=0.012).Noncardiovasculardeathnotsignificantlydifferent(P=0.45)CombinedendpointofcardiovasculardeathorhospitaladmissionforC...

AcuteHyperglycemiaStateIsAssociatedWithLowertPA-InducedRecanalizationRatesinStrokePatients

...erecanalization.Patientswhorecanalizedshowedloweradmissionglucoselevels(127vs146mg/dL;P=0.039)butnodifferencesinHbA1c(6.3%vs6.3%;P=0.896)orfructosamine(292vs293μmol/L;P=0.957)wereobserved.Othervariablesassociatedwithrecanalizationwereinitialdistalmiddlecerebralarteryocclusion(P=0.011)andplateletcou...

SmallAirwayMorphometryandImprovementinPulmonaryFunctionafterLungVolumeReductionSurgery

...vely.Despitesimilarbaselinecharacteristics,nonrespondershadagreaterEH(0.045vs.0.035mm,p=0.025),greaterEHadjustedforbasementmembraneperimeter(0.040vs.0.011,p=0.016),greaterepithelialareaadjustedforbasementmembranearea(0.561vs.0.499,p=0.040),andlessbullousdisease(1.7vs.2.6,p=0.011)comparedwithresponde...

Metabolicacidosishasdualeffectsonsodiumhandlingbyratkidney

...durationoftheexperimentasdescribedinMETHODS.A:urinaryNa+excretion(**P<0.002vs.control,*P<0.03vs.controlat24and72h,respectively).B:foodintake(*P<0.001vs.controland**P<0.0001vs.controlat24and48h,respectively).C:creatinineclearance.D:urinevolume.NH4ClloadingisassociatedwithdualeffectsonurinaryNa+excret...

一平苏－具有明确血管保护作用的ACEI

...者高血压患者西拉普利治疗组氨酰心安治疗组3020100***P0.05vs正常血压者人体研究显示：一平苏?显著逆转高血压状态下患者血管内皮功能的异常张力（用去甲肾后主动脉收缩的%）***P0.001vsSHRClozelM,etal.Hypertension5,532-540(1990)WKYSHR4天4月...

静脉桥血管病变的经皮介入治疗进展及问题

...CE的发生比例、non-QMI和QMI的发生在CUT组和对照组分别为25%vs.12%（P=0.036）,19.6%vs.7.9%（P=0.03），5.4vs.2.2（P=NS）。其中技术失败14例，这可能也是CUT组出现明显多的临床不良事件的原因之一。研究者认为超声消融血栓可能将血栓“打...