研究显示药物洗脱支架植入患者的主要临床预后优于金属裸支架
...andre-interventionthanBMSpatientsAstudyshowsthatdrug-elutingstents(DES)havesubstantiallylowerratesofdeath,heartattackandre-interventioninreal-worldpatientscomparedtobare-metalstents(BMS).Theresultsofthestudy,ComparisonofDrug-ElutingVersusBare-MetalStentsonLaterFrequencyofAcuteMyocardialInfarctionand...
行业资讯;临床快报;心胸外科ComputationalIdentificationofKeyBiologicalModulesandTranscriptionFactorsinAcuteLungInjury
...tionandintratrachealLPSproducessignificantlymoreinjurytothelungthaneitherinsultalone.WeusedglobalgeneontologyanalysistodetermineoverrepresentedbiologicalmodulesandcomputationaltranscriptionfactoranalysistoidentifyputativeregulatoryfactorsinvolvedinthismodelofALI.Results:Byintegratingexpressionprofil...
医源资料库;在线期刊;美国呼吸和危急护理医学;2006年第173卷第6期Sorsbyfundusdystrophypresentingwithchoroidalneovascularisationshowinggoodresponsetosteroidtreatment
...SMDownesOxfordEyeHospital,RadcliffeInfirmary,WoodstockRoad,OxfordOX26HE,UK;susan.downes@orh.nhs.ukAcceptedforpublication15May2003Keywords:choroidalneovascularisation;Sorsbyfundusdystrophy;steroidsSorsbyfundusdystrophy(SFD)isadominantlyinheritedmaculardystrophyinwhichbilateralcentralvisuallossoccursi...
医源资料库;在线期刊;英国眼科学杂志;2004年第88卷第3期ScreeningforObstructiveSleepApneainStrokePatients
...ecovery,butwhetherscreeningforOSAandtreatmentbycontinuouspositiveairwaypressure(CPAP)improvesneurologicaloutcomeisunknown.Weusedacost-effectivenessmodeltoestimatethemagnitudeofbenefitthatwouldbenecessarytomakepolysomnography(PSG)andOSAtreatmentcost-effectiveinstrokepatients.Methods—Adecisiontreemo...
医源资料库;在线期刊;中风学杂志;2005年第36卷第6期SrcFamilyKinaseInhibitorsBlockAmphiregulin-MediatedAutocrineErbBSignalinginNormalHumanKeratinocytes
...ealthSystem,AnnArbor,Michigan(J.T.E.)Abstractc-Srcpotentiatesproliferation,survival,andinvasivenessinresponsetoepidermalgrowthfactor(EGF)inhumanmammarycarcinomacells.Tyrosine(Tyr)845ofErbB1isphosphorylatedbySrcandhasbeenimplicatedincontrolofmalignantbehavior.Althoughseverallinesofevidencealsosuggest...
医源资料库;在线期刊;分子药理学杂志;2005年第67卷第4期Oligofructose-supplementedinfantcereal:2randomized,blinded,community-basedtrialsinPeruvianinfants
...tsCompany,Fremont,MI(FCandCE);andMassachusettsGeneralHospital,Boston(REK).2SupportedbyGerberProductsCompany.3AddressreprintrequeststoREKleinman,PediatricGastrointestinal/NutritionUnit,MassachusettsGeneralHospitalforChildren,55FruitStreet,Boston,MA02114.E-mail:rkleinman{at}partners.org.ABSTRACTBackgr...
医源资料库;在线期刊;美国临床营养学杂志;2003年77卷第4期舒利迭对COPD患者肺功能的影响
...[1]。舒利迭为吸入型长效β2受体激动剂沙美特罗(SU)和吸入型糖皮质激素丙酸氟替卡松(FP)的联合吸入制剂。两者在控制炎症和解除支气管痉挛方面具有较强的作用,并且没有全身皮质激素副作用。我科自2007年9月—...
医源资料库;在线期刊;中华现代内科学杂志;2008年第5卷第7期ANewRoleforGlucocorticoidsinSepticShockBalancingtheImmuneResponse
...UniversityofMunichMunich,Germany:Glucocorticoidsarethemostimportantimmunosuppressiveagentsinmedicine;theyareanestablishedtherapyforagreatvarietyofchronicinflammatorydiseasesaswellasintransplantationmedicine.Inacuteinflammation,particularlysepsisand/orsepticshock,theuseofhigh-dosecorticosteroidshas...
医源资料库;在线期刊;美国呼吸和危急护理医学;2003年第167卷第4期MMTVEnvencodesanITAMresponsiblefortransformationofmammaryepithelialcellsinthree-dimensionalculture
...tif(ITAM)-containingsignalingproteinsisnormallyrestrictedtohematopoietictissues.ThebasalactivityofITAM-containingproteinsismediatedthroughnegativeregulationbycoreceptorsrestrictedtohematopoietictissues.WehaveidentifiedanITAMsignalingdomainencodedwithintheenvgeneofmurinemammarytumorvirus(MMTV).Three-...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第3期三氧化二砷抗肿瘤作用机理研究及临床运用进展
...ARα融合蛋白是APL发病的主要分子基础,As2O3能增强Pml与SUMO1的共价结合,从而引发PML降解,诱导细胞凋亡。砷剂使PML-RARα,PML重新共定位于PODs并快速降解之。最初砷剂对APL的促凋亡作用在于特异性地降解其融合蛋白Pml-...
医源资料库;在线期刊;中华实用医药杂志;2008年第8卷第5期