EarlyNoninvasiveVentilationAvertsExtubationFailureinPatientsatRisk
...tdeCuresIntensivesiIntermedies,ServeidePneumologia,InstitutClínicdelTòraxáreadeVigilanciaIntensiva,HospitalClinic,Institutd‘InvestigacionsBiomediquesAugustPiiSunyer,UniversitatdeBarcelona,Barcelona,SpainABSTRACTRationale:Respiratoryfailureafterextubationandreintubationisassociatedwithincreasedm...
医源资料库;在线期刊;美国呼吸和危急护理医学;2006年第173卷第2期CharacterizationofCytolethalDistendingToxinofCampylobacterSpeciesIsolatedfromCaptiveMacaqueMonkeys
...endingtoxinactivity.Theidentityofeachisolatewasconfirmedonthebasisofphenotypicandgenotypicanalyses.ThepresenceofcytolethaldistendingtoxinwasconfirmedonthebasisofcharacteristicmorphologicalchangesinHeLacellsincubatedwithfilter-sterilizedwhole-celllysatesofreferenceandmonkeyCampylobacterisolatesandexa...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第2期HeterogeneityamongStrainsofDiffuselyAdherentEscherichiacoliIsolatedinBrazil
...oPauloInstitutoAdolfoLutzDepartamentodePatologia,FaculdadedeMedicinaVeterináriaeZootecnia,UniversidadedeSoPaulo,SoPaulo,BrazilDepartmentofMicrobiologyandImmunology,UniversityofMaryland,Baltimore,MarylandABSTRACTOnehundredtwelvediffuselyadherentEscherichiacolistrainsisolatedfromchildreninacasecontro...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第4期CorrelationbetweenhyperphosphatemiaandtypeIINa-Picotransporteractivityinklothomice
...phatehomeostasis.ThegoalofthepresentstudywastoinvestigatetheregulationofNa-Picotransportersinklothomutant(kl/kl)mice.Thekl/klmicedisplayedhyperphosphatemia,highplasma1,25(OH)2D3levels,increasedactivityoftherenalandintestinalsodium-dependentPicotransporters,andincreasedlevelsofthetypeIIa,typeIIb,andt...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第2期NADPHOxidase–DependentSuperoxideProductionIsAssociatedWithCarotidIntima-MediaThicknessinSubjectsFreeofClinicalAtheroscleroticDisease
...dicine,UniversityofNavarra,Pamplona,Spain.CorrespondencetoDrGuillermoZalba,áreadeFisiopatologíaCardiovascular,CentrodeInvestigaciónMédicaAplicada,AvdaPíoXII55,31008Pamplona,Spain.E-mailgzalba@unav.esAbstractObjective—Oxidativestressplaysacriticalroleinthepathogenesisofatherosclerosis.TheNADPH...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第7期Caveolin-1FacilitatesMechanosensitiveProteinKinaseB(Akt)SignalingInVitroandInVivo
...iously,wedemonstratedamechanosensitiveactivationofphosphoinositide3-kinase(PI3-K)/proteinkinaseB(Akt)resultinginp27Kip1transcriptionaldownregulationandcellcycleentryofvascularsmoothmusclecells(VSMC).Inthisstudy,wefurtherelucidatedthesignalingfromoutside-intowardPI3-K/Aktinvitroandinaninvivomodelofel...
医源资料库;在线期刊;循环研究杂志;2005年第95卷第4期HIV-1ProteaseandReverse-TranscriptaseMutations:CorrelationswithAntiretroviralTherapyinSubtypeBIsolatesandImplicationsforDrug-ResistanceSurvei
...1sequencesfrompersonswithandwithoutprevioustreatmentwithproteaseinhibitors(PIs),nucleosideRTinhibitors(NRTIs),andnonnucleosideRTinhibitors(NNRTIs).Treatment-associatedmutationsinproteaseisolatesfrom5867personsandRTisolatesfrom6247personswerecategorizedbywhethertheywerepolymorphic(prevalence,0.5%)inu...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第15期Anti-CD63antibodiessuppressIgE-dependentallergicreactionsinvitroandinvivo
...)inducessecretionofpreformedallergymediators(degranulation)andsynthesisoflipidmediatorsandcytokines.Degranulationproducesmanysymptomsofimmediate-typeallergicreactionsandismodulatedbyadhesiontosurfacescoatedwithspecificextracellularmatrix(ECM)proteins.Thesignalsinvolvedinthismodulationaremostlyunknow...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第3期户尘螨过敏原双向免疫印迹指纹图谱研究
...inlu,ZhangHongyu,WangJinglan,etal. DepartmentofAllergy,PUMCHospital,CAMSPUMC,Beijing100730. 【Abstract】ObjectiveToexploreDermatophagoidespteronyssinus(D.pteronyssinus)allergensfingerprintˉingwithtwo-dimensional(2D)electrophoresisand2Dimmunoblotting.MethodsD.pteronys...
合作平台;在线期刊;中华现代临床医学杂志;2004年第2卷第9A期InsulinSignalinginArteriesPreventsSmoothMuscleApoptosis
...lcells,11andmonocytes.12Thiseffectismediatedbyphosphatidylinositol3-kinase(PI3K)andthedownstreamsignalAkt/proteinkinaseB(PKB)butdoesnotrequireactivationofmitogen-activatedproteinkinases.13VSMCapoptosisoccursinatheroscleroticlesionsinhumans,rabbits,andpigs,andinthethickenedintimaformedafterpercutaneo...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第4期