Regulationofproteolysisandoptimalproteinaccretioninextremelyprematurenewborns
...ntedthat9099%ofELBWinfantshaveweightsthatarelessthanthe10thpercentileat36wkcorrectedgestationalage(1,2).OtherlargegroupshavealsoreportedpoorgrowthoutcomesforELBWinfants(3).ImprovinggrowthinELBWinfantswillrequireabetterunderstandingofhowtolimitproteolysisandachievebetterproteinaccretioninthispo...
医源资料库;在线期刊;美国临床营养学杂志;2007年85卷第2期OverexpressionofHyaluronanintheTunicaMediaPromotestheDevelopmentofAtherosclerosis
...ursuedbydigestionwithproteasefromStreptomycesGriseus(1mg/mL,Sigma)overnightat37°Candfollowedbyheatinactivation(100°Cfor30minutes).Aftercentrifugation(30000gfor10minutes),theHAcontentinthesupernatantswasmeasuredbyanHAELISA(ChugaiDiagnosticsScienceCo).Thedetectionlimitoftheassaywas10ng/mLandtheintra...
医源资料库;在线期刊;循环研究杂志;2005年第95卷第3期DistinctiveroleofStat3andErk-1/2activationinmediatinginterferon-inhibitionofTGF-1action
...ainedactivationofErk-1/2andsignaltransducerandactivatoroftranscription-3(Stat3).BlockadeofErk-1/2activationwithanMek1inhibitorabolishedtheinhibitoryeffectofIFN-on-SMAexpression,whereasinhibitionofStat3activationhadnoinfluence.ConstitutiveactivationofErk-1/2byectopicexpressionofactivatedMek1mimickedI...
医源资料库;在线期刊;美国生理学杂志;2006年第289卷第5期AcuteHemorrhagicPericarditisinaChildwithPneumoniaDuetoChlamydophilapneumoniae
...venintravenouslyfor4days;anti-inflammatorytherapywithibuprofenwasalsogiven.At3weeksafterremovalofthepericardialdrain,effusiondidnotreaccumulateandtheclinicalstatusimproved.Thepatientwasdischargedfromthehospitalafter14days.FurtherserologicworkuprevealedpositiveimmunoglobulinG(IgG)andIgAantibodyresult...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期ImmuneReconstitutionandClearanceofHumanAdenovirusViremiainPediatricStem-CellRecipients
...plicate.HAdVlysatewasdilutedto100×TCID50,addedtoeachwell,andincubatedfor1hat37°C.Hep2orA549cellswereadded,andwellswerescoredforCPEafter7daysofculture.TheneutralizingtiterwasthehighestserumdilutionatwhichCPEwasnolongerobserved.Increasesintiters(4-foldincrease)ofNAbsagainsttheserotypewithwhichthepat...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第4期COX-2activitytransientlycontributestoincreasedwaterandNaClexcretioninthepolyuricphaseafterreleaseofureteralobstruction
...QP3,Na-K-2Clcotransportertype2(NKCC2),andNa-K-ATPase3daysafterreleaseofBUO.At3daysafterreleaseofBUO,ratsexhibitedpolyuria,dehydrationandurineandIMtissueosmolalityweredecreased.TherewereinversechangesofCOX-1andCOX-2intheIM:COX-2mRNA,protein,andactivityincreased,whileCOX-1mRNAandproteindecreased.Parec...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第5期膝关节交锁419例原因分析
...s);ACLpartialorcompletelytears0.95%(4kness);andPVNS0.72%(3kness).At3monthsoffollow-up,themajorityoftheknees(414knees,98.8%)regainedfullrangeofmovement.ConclusionThemaincausesoflockedkneesaremeniscallesions,loosebody,synovialandfatpadlesions,ligamenttearsandPVNSetc.Impingement...
合作平台;在线期刊;中华中西医杂志;2004年第5卷第23期;论著MechanicalStretchSimulatesProliferationofVenousSmoothMuscleCellsThroughActivationoftheInsulin-LikeGrowthFactor-1Receptor
...IGF-1Rexon3knockout,whereasthe574-bpfragmentindicatedtheintactIGF-1Rgene.12At3months,micewithIGF-1RLoxP+/+ER-Cre+/-orcontrolmice(IGF-1RLoxP+/+)wereinjectedintraperitoneally(i.p.)with1or3mgtamoxifen(10mg/mLincornoil)for7days.IGF-1RdeletionwasdetectedbyRT-PCR,Westernblot,andimmunohistochemistry.VeinGr...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第8期自闭小切口非超声乳化白内障人工晶状体手术
...largerthantheouterincision,wasformedthroughtheenteringofthecornealknife.At3or9o‘clockatransparentcorneaauxiliaryincisionwasmade.Theincisionclosedwithoutsu-tureafteroperation.ThesurgicalknifewasAmericanonetimewoundlessknife.Results3daysaftersurgery,visionin276eyes(87%)wasbetterthan0.5and301...
合作平台;在线期刊;中华现代眼科学杂志;2004年12月第4期;论著高血压的临床药物治疗
...逸。(2)仅作用于血管紧张素Ⅱ型(AT1)受体,不影响AT2、AT3、AT4受体可能介导的有益作用;(3)对激肽系统无影响,咳嗽不良反应与安慰剂相似;(4)其中氯沙坦具有尿酸排泄作用。LIFE实验证实,氯沙坦与阿替洛尔相比,卒中...
医源资料库;在线期刊;中华现代内科学杂志;2006年第3卷第2期