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CD44V-mRNA在直肠癌微转移中作用的临床研究
...4VmRNAinperipheralbloodofrectumcancerafterradicalsurgeryDINGJian-wu,LUOJun-ming,SHENWei,etal.TheSecondAffiliatedHospitalofNanchangUniversity,Nanchang330006，China【Abstract】ObjectiveToevaluatetheclinicalsignificanceofquantitativeanalysisCD44vmRNAinperipheralbloodofrectumcancerafterradicalsurgery...
医源资料库；在线期刊；中华实用医药杂志；2008年第8卷第8期 -
Thedistributionsofmitochondriaandsodiumchannelsreflectthespecificenergyrequirementsandconductionpropertiesofthehumanopticnervehead
...ofvoltagegatedNa+channels(subtypesNav1.1,1.3,and1.6)intheunmyelinated,prelaminar,andlaminaropticnervewasfound.Thisdistributionco-localisedbothwithareasofhighCOXactivityandstrongimmunolabellingforCOXsubunitsIandIV.Conclusions:Increasednumbersofmitochondriaintheprelaminaropticnervehavepreviouslybeenin...
医源资料库；在线期刊；英国眼科学杂志；2004年第88卷第2期 -
QuantitativeEvaluationofHumanOpioidReceptorDesensitizationUsingtheOperationalModelofDrugAction
...lecule)orheterologous(causedbyactivationofotherreceptors).Inthisstudy,weexaminedthemolecularmechanismsoftherapidhomologousdesensitizationofthehumanopioidreceptor(hDOR).Stimulationoftheopioidreceptor(DOR)byanagonist,leadstoactivationofinhibitoryGi/oproteins,anddissociationofGisubunitsfromdimers(Quock...
医源资料库；在线期刊；分子药理学杂志；2007年第69卷第5期 -
OSU-03012PromotesCaspase-IndependentbutPERK-,CathepsinB-,BID-,andAIF-DependentKillingofTransformedCells
【关键词】TransformedCellsWedeterminedonemechanismbywhichtheputativephosphoinositide-dependentkinase(PDK)-1inhibitor2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl}acetamide(OSU-03012)killedprimaryhumangliomaandothertransformedcells.OSU-03012causedadose-dependentin...
医源资料库；在线期刊；分子药理学杂志；2006年第68卷第8期 -
Structure-FunctionStudiesofAllostericAgonismatM2MuscarinicAcetylcholineReceptors
...tthesemutationshadaprofoundinhibitoryeffectontheprototypicalmodulatorsgallamine,alcuronium,andheptane-1,7-bis-[dimethyl-3‘-phthalimidopropyl]-ammoniumbromide(C7/3-phth)butminimaleffectsontheorthostericantagonist[3H]N-methylscopolamine.Incontrast,theallostericagonists4-I-[3-chlorophenyl]carbamoylox...
医源资料库；在线期刊；分子药理学杂志；2007年第69卷第8期 -
AntibodiesfromPatientswithMelioidosisRecognizeBurkholderiamalleibutNotBurkholderiathailandensisAntigensintheIndirectHemagglutinationAssay
...eywere14yearsofageordeclinedtoparticipate.EthicalapprovalwasobtainedfromtheMinistryofPublicHealth,RoyalGovernmentofThailand.Pooledantigenswerepreparedfromthefollowingisolates:(i)B.pseudomalleiclinicalisolates199aand207a,obtainedfrompatientswithmelioidosisinnortheastThailand;(ii)B.thailandensisisolat...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第9期 -
儿童围术期焦虑的心理行为干预
...许患儿随意触摸房间内仪器及输液用具等。参观时间约10min。手术当日由同一麻醉医师带领患儿入手术室，家长在手术室外等候。 1.2.3对照组术前不给予患儿任何干预措施，手术当日由医生带入手术室。 1.3观察项目（1）...
资料库；在线期刊；中华现代儿科学杂志；2005年第2卷第3期 -
RegulationofLymphocyteApoptosisbyInterferonRegulatoryFactor4(IRF-4)
...ignificantlyenhancedapoptoticresponseonFasreceptorengagement.AsystematicexaminationofthedownstreameffectorsofFassignalinginIRF-4–transfectedcellsdemonstratesanincreasedactivationofcaspase-8,aswellasanincreaseinFasreceptorpolarization.WedemonstratethatIRF-4–deficientmicedisplaydefectsinactivation...
医源资料库；在线期刊；实验医学杂志；2003年第197卷第3期 -
GeneticDiversityamongTypeemm28GroupAStreptococcusStrainsCausingInvasiveInfectionsandPharyngitis
...nbiology.Nucleotidesequencevariationintheemmgene(encodesMprotein)wasalsoexamined.Onlythreeallelicvariantswereidentifiedinthehypervariableportionoftheemm28gene.Allbutonestrainhadthesameinferredaminoacidsequenceinthefirst100aminoacidsofthematureM28protein.Incontrast,sizedifferencesintheemm28geneandinf...
医源资料库；在线期刊；微生物临床杂志；2005年第43卷第8期 -
γ-谷氨酰转肽酶（GGT）基因克隆及在原核生物中表达*
...ma;-gammaglutamyltranspeptidaseinprocaryoteSHILin-mei,ZHANZha-jun,WANGDong-ming.LishuiProfessionandTechnologyCollege,Zhejiang323000,China【Abstract】Higherpuretheanineabstractedfromteaissocostly,thechemicsynthesisoftheanineisacomplicatedcraftworkandtheloweroutputoftheaninebyplanttissueculture.Soit...
医源资料库；在线期刊；中华医药杂志；2009年第9卷第8期