Understandingglobinregulationin?-thalassemia:it’sassimpleas,?,,
DepartmentofMedicineandDepartmentofGeneticsandDevelopment,ColumbiaUniversityCollegeofPhysiciansandSurgeons,NewYork,NewYork,USA.AbstractAvastexcessof-globinproductionandinadequate-globincompensationleadtothedevelopmentofsevereanemiainhuman?-thalassemia.Newlyidentifiedmodifiersof-and-globinsynthesisan...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第6期Mannanbindinglectinasanadjuncttoriskassessmentformyocardialinfarctioninindividualswithenhancedrisk
...avogur,IcelandInflammationcanpredisposetomyocardialinfarction(MI),andmannanbindinglectin(MBL)promotesphagocyticclearanceofinflammatoryagents,butthepredictivevalueofMBLlevelsforMIisnotknown.MBLwasanalyzedinsubgroupsofthepopulation-basedReykjavikstudy,acohortof19,381participantsrecruitedfrom1967.MBLle...
医源资料库;在线期刊;实验医学杂志;2005年第201卷第1期Acrucialroleforinterleukin(IL)-1intheinductionofIL-17–producingTcellsthatmediateautoimmuneencephalomyelitis
1ImmuneRegulationResearchGroup2AdjuvantResearchGroup,SchoolofBiochemistryandImmunology,TrinityCollege,Dublin2,IrelandItwasrecentlydemonstratedthatinterleukin(IL)-23–drivenIL-17–producing(ThIL-17)Tcellsmediateinflammatorypathologyincertainautoimmunediseases.Weshowthattheinductionofantigen-specifi...
医源资料库;在线期刊;实验医学杂志;2006年第203卷第7期大动脉僵硬度新指标CAVI的临床应用
...VI指标的稳定性。结果:CAVI指标在正常人与冠心病、高血压及其他疾病的人群之间有显著差异,但采用偏相关统计方法,在控制年龄因素的情况下,正常人组与各患病组之间无显著差异;CAVI检测值与性别无相关性,但与年龄呈...
医源资料库;在线期刊;中国民康医学;2008年第20卷第15期Cyclooxygenases,microsomalprostaglandinEsynthase-1,andcardiovascularfunction
...aSchoolofMedicine,Philadelphia,Pennsylvania,USA.2DepartmentsofPhysiologyandBiochemistry,Queen’sUniversity,Kingston,Ontario,Canada.AbstractWeinvestigatedthemechanismsbywhichinhibitorsofprostaglandinG/Hsynthase-2(PGHS-2;knowncolloquiallyasCOX-2)increasetheincidenceofmyocardialinfarctionandstroke.The...
医源资料库;在线期刊;临床研究杂志;2006年第116卷第5期MolecularCharacterizationofDiphtheriaToxinRepressor(dtxR)GenesPresentinNontoxigenicCorynebacteriumdiphtheriaeStrainsIsolatedintheUnitedKingd
RespiratoryandSystemicInfectionLaboratory,SpecialistandReferenceMicrobiologyDivision,HealthProtectionAgency,LondonHealthProtectionAgency,HeartlandsHospital,andDivisionofImmunityandInfection,MedicalSchool,UniversityofBirmingham,BirminghamUnitedKingdomABSTRACTNontoxigenicstrainsofCorynebacteriumdiphth...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第1期TheL-typecalciumchannelintheheart:thebeatgoeson
InstituteofMolecularPharmacologyandBiophysics,UniversityofCincinnatiCollegeofMedicine,DepartmentofSurgery,Cincinnati,Ohio,USA.AbstractSydneyRingerwouldbeoverwhelmedtodaybytheimplicationsofhissimpleexperimentperformedover120yearsagoshowingthattheheartwouldnotbeatintheabsenceofCa2+.Fascinationwithther...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第12期99mTcSestamibiBreastImagingfortheExaminationofPatientswithDenseandFattyBreasts:MulticenterStudy1
...,Canada(J.S.S.);andDuPontPharmaceuticalsCompany,331TrebleCoveRd,500-2,NorthBillerica,MA01862(S.B.H.).Theparticipatinginvestigatorsandhospitalsarelistedattheendofthisarticle.Fromthe1996RSNAscientificassembly.ReceivedJan2,2001;revisionrequestedFeb7;revisionreceivedJun12;acceptedJul5.Allauthorsreceived...
医源资料库;在线期刊;放射学杂志;2003年1月第226卷第1期CharacterizationofClostridiumbotulinumStrainsAssociatedwithanInfantBotulismCaseintheUnitedKingdom
DepartmentofFoodMicrobiologyandToxicology,FoodResearchInstitute,UniversityofWisconsin,1925WillowDrive,Madison,Wisconsin53706-1187CarpendersClose,Harpenden,HertsAL53HNUnitedKingdomFoodborneDiseasesBranch,MicrobiologicalSafetyDivision,FoodStandardsAgency,AviationHouse,125Kingsway,LondonWC2B6NH,UnitedK...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第6期实时组织弹性成像与超声BI-RADS分级法在乳腺肿瘤性疾病诊断中的对比研究
...腺结节的实时组织弹性成像资料进行回顾分析,并与超声BI-RADS分级法对比,探讨两种方法在乳腺实性结节良恶性鉴别诊断中的价值。方法130例女性乳腺结节患者,常规高频彩超图像进行BI-RADS分级[1],而后对实时弹性图像评分,...
医源资料库;在线期刊;中华现代影像学杂志;2012年第9卷第4期